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84 results for “Larval zebrafish”
Data from: In vivo assessment of respiratory burst inhibition by xenobiotic exposure using larval zebrafish
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Data accompanying The preoptic area and dorsal habenula jointly support homeostatic navigation in larval zebrafish
<p>"<strong>The preoptic area and dorsal habenula jointly support homeostatic navigation in larval zebrafish"</strong></p><p>This repository contains the data presented in Palieri et al, 2023 (preprint <a href="https://www.biorxiv.org/content/10.1101/2023.05.18.541289v1">https://www.biorxiv.org/content/10.1101/2023.05.18.541289v1</a> ).</p><p>The data is organized into the following subfolders:</p><ul><li><strong>Behavior</strong>: This folder contains all the data related to freely swimming experiments, including both spatial (spatial_gradient subfolder) and temporal (temporal_gradient subfolder) temperature gradients. The former also includes data from chemogenetic and 2-photon mediated ablations.</li><li><strong>Imaging</strong>: Within this folder, you will find data obtained through confocal microscopy (in the confocal subfolder) and lightsheet microscopy (in the lightsheet subfolder). Confocal imaging was used to verify proper habenula ablation (dHb_preablation and dHb_postablation). Lightsheet imaging was performed for functional calcium imaging experiments during temperature and salinity gradients. The lightsheet subfolder is further subdivided into long and short experiments, with each fish having its own dedicated folder. Inside each fish's folder, you can access imaging data (traces, local coordinates, coordinates in reference space, along with relevant indexes such as the reliability index) and behavioral data (acquired using the Stytra software).</li></ul><p>Please contact Ruben Portugues for further information.</p>
A quantitative approach to study the adaptation of rhythmic eye movements in larval zebrafish
<p>Optokinetic nystagmus; quick phases; spontaneous saccades; saccadic adaptation; congenital ocular motor apraxia</p>
Severe hypoxia exposure inhibits larval brain development but does not affect the capacity to mount a cortisol stress response in zebrafish
<p>Fish nursery habitats are increasingly hypoxic and the brain is recognized as highly hypoxia-sensitive, yet there is a lack of information on the effects of hypoxia on the development and function of the larval fish brain. Here, we tested the hypothesis that by inhibiting brain development, larval exposure to severe hypoxia has persistent functional effects on the cortisol stress response in zebrafish (<i>Danio rerio</i>). Exposing 5 days post-fertilization (dpf) larvae to 10% dissolved O<sub>2</sub> (DO) for 16 h only marginally reduced survival, but it decreased forebrain neural proliferation by 55%, and reduced the expression of <i>neurod1</i>, <i>gfap,</i> and <i>mbpa, </i>markers of determined neurons, glia, and oligodendrocytes, respectively. The 5 dpf hypoxic exposure also elicited transient increases in whole body cortisol and in <i>crf</i>, <i>uts1</i>, and <i>hsd20b2</i> expression, key regulators of the endocrine stress response. Hypoxia exposure at 5 dpf also inhibited the cortisol stress response to hypoxia in 10 dpf larvae and increased hypoxia tolerance. However, 10% DO exposure at 5 dpf for 16h did not affect the cortisol stress response to a novel stressor in 10 dpf larvae or the cortisol stress response to hypoxia in adult fish. Therefore, while larval exposure to severe hypoxia can inhibit brain development, it also increases hypoxia tolerance. These effects may transiently reduce the impact of hypoxia on the cortisol stress response but not its functional capacity to respond to novel stressors. We conclude that the larval cortisol stress response in zebrafish has a high capacity to cope with severe hypoxia-induced neurogenic impairment.</p>
Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function - behavior data input files
<p>Unprocessed (tracking) larval zebrafish behavioral data from mutants with microexons removed. All genes are grouped by their beginning letter, and two runs are included for most mutants.</p>
Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function - imaging stacks
<p>Results of brain activity mapping for zebrafish mutants with microexons removed. Both brain activity and structural data is included. These stacks are the significant signal that differs between the groups. They are compatable with the Z-Brain matlab viewer from Randlett, et al, 2015 Nature Methods.</p>
Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function - behavior data output
<p>Graphs and quantification of larval zebrafish behavioral data from mutants with microexons removed. All genes are grouped by their beginning letter, and two runs are included for most mutants.</p>
Dataset for Uncovering multiscale structure in the variability of larval zebrafish navigation V2
<p>This is the dataset for reproducing the results from the paper "Uncovering multiscale structure in the variability of larval zebrafish navigation". The github repository for the code can be found here - https://github.com/GautamSridhar/Markov_Fish</p>
Ionic conductances driving tonic firing in Purkinje neurons of larval zebrafish
<p>This contains all the analysed dataset related to the publication in Journal of Physiology; Jadhav et al., 2025. Folders contain data used for each figure. Scripts to analyse eletrophysiology recordings and generate figures added in a separate folder.</p>
Datasets of larval zebrafish behaviour, Mullen et al., 2023
<p>Datasets containing videos of larval zebrafish behavior, as described in Mullen et al., 2023.</p>
Severe hypoxia exposure inhibits larval brain development but does not affect the capacity to mount a cortisol stress response in zebrafish
Open the record for dataset details and reuse information.
Data from: Coordination of fictive motor activity in the larval zebrafish is generated by non-segmental mechanisms
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Data from: How body torque and Strouhal number change with swimming speed and developmental stage in larval zebrafish
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Single cell gene expression profiling of prenoplastic cells and myeloid cells during tumour initiation wihin a larval zebrafish model of skin oncogenis driven by inducible HRASG12V
GEO Series GSE232900. Danio rerio. 6 samples. Type: Expression profiling by high throughput sequencing.
Transgenerational inheritance of impaired larval T cell development in zebrafish
GEO Series GSE98647. Danio rerio. 36 samples. Type: Methylation profiling by high throughput sequencing.
Single-cell gene expression profie of developing photoreceptor cells in larval zebrafish
GEO Series GSE250379. Danio rerio. 1 samples. Type: Expression profiling by high throughput sequencing.
gabrg2-KO whole zebrafish larval brain differential expression analysis
GEO Series GSE134951. Danio rerio. 6 samples. Type: Expression profiling by high throughput sequencing.
Assessing mechanisms driving phenol isopropylated phosphate (IPP)-induced larval photomotor response deficits in zebrafish
GEO Series GSE272355. Danio rerio. 16 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profiles of larval zebrafish under homeostatic conditions, after induced epithelial cell loss, and during tissue repair.
GEO Series GSE140839. Danio rerio. 12 samples. Type: Expression profiling by high throughput sequencing.
Cholangiocytes contribute to hepatocyte regeneration after partial liver injury in larval zebrafish
GEO Series GSE272484. Danio rerio. 7 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.