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Dataset results
60 results for “MOTOR RESPONSES”
TMS over the posterior cerebellum modulates motor cortical excitability in response to facial emotional expressions
<p>Evidence suggests that the posterior cerebellum is involved in emotional processing. Specific mechanisms by which the cerebellum contributes to the perception of and reaction to the emotional state of others are not well-known. It is likely that perceived emotions trigger anticipatory/preparatory motor changes. However, the extent to which the cerebellum modulates the activity of the motor cortex to contribute to emotional processing has not been directly investigated. In this study, we assessed whether the activity of the posterior cerebellum influences the modulation of motor cortical excitability in response to emotional stimuli. To this end, we transiently disrupted the neural activity of the left posterior cerebellum using 1 Hz repetitive transcranial magnetic stimulation (rTMS) and examined its effect on motor cortical excitability witnessed during emotional face processing (in comparison to the effects of sham rTMS). Motor excitability was measured as TMS-based motor evoked potentials (MEPs) recorded from bilateral first dorsal interosseous (FDI) muscles during the viewing of negative emotional (i.e. fearful) and neutral facial expressions. In line with previous evidence, we found that MEP amplitude was increased during the viewing of fearful compared to neutral faces. Critically, when left posterior cerebellar activity was transiently inhibited with 1 Hz rTMS, we observed a reduction in amplitude of MEPs recorded from the contralateral (right) motor cortex during the viewing of emotional (but not neutral) faces. In turn, inhibition of the left posterior cerebellum did not affect the amplitude of MEPs recorded from the ipsilateral motor cortex. Our findings suggest that the posterolateral (left) cerebellum modulates motor cortical response to negative emotional stimuli and may serve as an interface between limbic, cognitive, and motor systems.</p>
Increased inertia triggers linear responses in motor cortices during large-extent movements – an fNIRS study
<pre>Representative video footage of actual experimental scenarios. </pre>
Direct Measurement of Motor Cortical Responses to tDCS
ClinicalTrials.gov study NCT04759898. IPD Sharing: NO. Countries: 1. Publications: 0.
Comparison of Motor and Sensory Response With Interstim Stimulation
ClinicalTrials.gov study NCT00943904. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Lighting and Human Response in Motor Time, Autonomic Nervous System, and Emotion
ClinicalTrials.gov study NCT03144791. IPD Sharing: NO. Countries: 0. Publications: 3.
Targeting EGLN2/PHD1 protects motor neurons and normalizes the astrocytic interferon response.
GEO Series GSE260913. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
The BMP antagonist Gremlin1 contributes to the development of cortical excitatory neurons, motor balance and fear responses
GEO Series GSE152952. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Branched chain amino acid sufficiency is necessary for proper luteinizing hormone response, testosterone synthesis, and motor coordination
GEO Series GSE309126. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Data from: Temporal specificity of the initial adaptive response in motor adaptation
Repeated exposure to a novel physical environment eventually leads to a mature adaptive response whereby feedforward changes in motor output mirror both the amplitude and temporal structure of the environmental perturbations. However, adaptive responses at the earliest stages of learning have been found to be not only smaller, but systematically less specific in their temporal structure compared to later stages of learning. This observation has spawned a lively debate as to whether the temporal structure of the initial adaptive response is, in fact, stereotyped and non-specific. To settle this debate, we directly measured the adaptive responses to velocity-dependent and position-dependent force-field perturbations (vFFs and pFFs) at the earliest possible stage of motor learning in humans–after just a single-movement exposure. In line with previous work, we found these earliest stage adaptive responses to be more similar than the perturbations that induced them. However, the single-trial adaptive responses for vFF and pFF perturbations were clearly distinct, and the disparity between them reflected the difference between the temporal structure of the perturbations that drove them. Critically, we observed these differences between single-trial adaptive responses when vFF and pFF perturbations were randomly intermingled from one trial to the next within the same block, indicating perturbation response specificity at the single trial level. These findings demonstrate that the initial adaptive responses to physical perturbations are not stereotyped. Instead, the neural plasticity in sensorimotor areas is sensitive to the temporal structure of a movement perturbation even at the earliest stage in learning. This insight has direct implications for the development of computational models of early-stage motor adaptation and the evolution of this adaptive response with continued training.
Effect of Transcutaneous Nerve Stimulation on Primary Motor Cortex to Modulate Cortical Excitability and Hemodynamic Response During Implicit Motor Learning: A TMS and NIRS Study
ClinicalTrials.gov study NCT02115841. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Combining Motor Imagery With Action Observation Does Not Lead to a Greater Autonomic Response Than Motor Imagery Alone During Simple and Functional Movements: a Randomized Controlled Trial.
ClinicalTrials.gov study NCT03232879. IPD Sharing: NO. Countries: 1. Publications: 0.
Hemodynamic Response and Motor Functions Following Transcranial Direct Current Stimulation in Acute Stroke
ClinicalTrials.gov study NCT04051658. IPD Sharing: NO. Countries: 1. Publications: 0.
Prediction of STN DBS Motor Response in PD
ClinicalTrials.gov study NCT04093908. IPD Sharing: YES. Countries: 1. Publications: 0.
The Effect Of E2007 On Pharmacodynamic Responses To Levodopa Among Patients With Parkinson's Disease Who Experience Dyskinesia And Motor Fluctuations
ClinicalTrials.gov study NCT00451633. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Motor Cortex Plasticity Response to Theta-Burst Stimulation After Ketone Monoester Supplementation
ClinicalTrials.gov study NCT06799260. IPD Sharing: YES. Countries: 1. Publications: 0.
Motor Response to Sildenafil in PD
ClinicalTrials.gov study NCT01941732. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Reliability, Validity and Responsiveness of the Upright Motor Control Test in Patients With Stroke
ClinicalTrials.gov study NCT03471598. IPD Sharing: NO. Countries: 1. Publications: 0.
Plasticity of Grey and White Matter in Response to Motor Skill Training in Healthy Individuals and Those With Spinal Cord Injury
ClinicalTrials.gov study NCT02148887. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Phase 2 Clinical Study of KW-6500 in Parkinson's Disease Patients With Motor Response Complication on Levodopa Therapy
ClinicalTrials.gov study NCT00610103. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Long-Term, Safety Study With a Flexible Dose Range of KW-6002 in Patients With Motor Response Complications on Levodopa/Carbidopa Therapy
ClinicalTrials.gov study NCT00955045. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.