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435
datasets available to search
ShareScore release 0.9.0
Dataset results
435 results for “NAFLD”
Endoscopic Ultrasound(EUS)-Guided TRUCUT Biopsy (EUS-TCB) of Suspected Nonalcoholic Fatty Liver Disease(NAFLD.)
ClinicalTrials.gov study NCT00586313. IPD Sharing: NO. Countries: 1. Publications: 2.
Prevention and Reversion of NAFLD in Obese Patients With Metabolic Syndrome by Mediterranean Diet and Physical Activity
ClinicalTrials.gov study NCT04442620. IPD Sharing: NO. Countries: 1. Publications: 1.
A Study of the Efficacy and Safety of PXL770 Versus Placebo After 12 Weeks of Treatment in Patients With NAFLD
ClinicalTrials.gov study NCT03763877. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Study of the Safety and Tolerability of AXA1125 and AXA1957 in Subjects With Non-Alcoholic Fatty Liver Disease (NAFLD)
ClinicalTrials.gov study NCT04073368. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Safety And Efficacy Study Of Orally Administered Epeleuton In Patients With NAFLD
ClinicalTrials.gov study NCT02941549. IPD Sharing: Not stated. Countries: 3. Publications: 1.
Study of INT-747 in Patients With Diabetes and Presumed NAFLD
ClinicalTrials.gov study NCT00501592. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Saroglitazar Magnesium 4 mg in the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in Women With PCOS (EVIDENCES VII)
ClinicalTrials.gov study NCT03617263. IPD Sharing: NO. Countries: 2. Publications: 1.
A Study of IDN-6556 in Subjects With NAFLD and Raised Transaminases
ClinicalTrials.gov study NCT02077374. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Fucoidan Improves the Metabolic Profiles of Patients With Non-alcoholic Fatty Liver Disease (NAFLD)
ClinicalTrials.gov study NCT02875392. IPD Sharing: NO. Countries: 1. Publications: 1.
Efficacy of a Natural Components Mixture in the Treatment of Non Alcoholic Fatty Liver Disease (NAFLD)
ClinicalTrials.gov study NCT02369536. IPD Sharing: NO. Countries: 1. Publications: 1.
MicroRNA-574-5p targeting HOXC6 expression inhibits the hepatocyte lipid uptake to alleviate NAFLD
<p>In recent times, the non-alcoholic fatty liver disease (NAFLD) is increasing worldwide. Increasing evidence supports the role of miRNAs in the pathogenesis of NAFLD. The miR-574-5p has been shown to be involved in lipid metabolism. However, studies on the correlation between miR-574-5p and NAFLD are lacking. Hence, in this study, we wanted to investigate <strong>whether miR-574-5p is associated with the pathogenesis of NAFLD</strong>. Through various <em>in vivo</em> and <em>in vitro</em> experiments, we found that miR-574-5p can inhibit lipid accumulation and lipid formation by targeting the HOXC6 3' UTR. We believe that our study makes a significant contribution to the literature because <strong>this study is the first to show that miR-574-5p is downregulated in liver tissue in </strong><strong>a</strong><strong> mouse NAFLD model</strong>. Further, understanding the miRNAs and their targets that regulate NAFLD may help us better understand the disease and lead to the design of a potential therapeutic against NAFLD in the future.In recent times, the non-alcoholic fatty liver disease (NAFLD) is increasing worldwide. Increasing evidence supports the role of miRNAs in the pathogenesis of NAFLD. The miR-574-5p has been shown to be involved in lipid metabolism. However, studies on the correlation between miR-574-5p and NAFLD are lacking. Hence, in this study, we wanted to investigate <strong>whether miR-574-5p is associated with the pathogenesis of NAFLD</strong>. Through various <em>in vivo</em> and <em>in vitro</em> experiments, we found that miR-574-5p can inhibit lipid accumulation and lipid formation by targeting the HOXC6 3' UTR. We believe that our study makes a significant contribution to the literature because <strong>this study is the first to show that miR-574-5p is downregulated in liver tissue in </strong><strong>a</strong><strong> mouse NAFLD model</strong>. Further, understanding the miRNAs and their targets that regulate NAFLD may help us better understand the disease and lead to the design of a potential therapeutic against NAFLD in the future.</p>
Exercise Study in Subjects With NAFLD
ClinicalTrials.gov study NCT03995056. IPD Sharing: NO. Countries: 1. Publications: 2.
Clinical Epidemiology of NAFLD in Children and Adolescents
ClinicalTrials.gov study NCT05526274. IPD Sharing: NO. Countries: 1. Publications: 1.
Abundance and Distribution of Lipids and Proteins in Nonalcoholic Fatty Liver Disease (NAFLD)
ClinicalTrials.gov study NCT00983463. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effects of Tomato Consumption on Steatosis, Intestinal Function and Glucose and Lipid Metabolism in Subjects With NAFLD
ClinicalTrials.gov study NCT06389851. IPD Sharing: NO. Countries: 1. Publications: 4.
A Gender and Culturally Specific Approach to Reduce NAFLD in Mexican-American Men
ClinicalTrials.gov study NCT04186260. IPD Sharing: YES. Countries: 1. Publications: 10.
Effects of Time-restricted Hypocaloric Diet in Patients with NAFLD
ClinicalTrials.gov study NCT05866744. IPD Sharing: NO. Countries: 1. Publications: 1.
Subclinical Cardiovascular Changes in NAFLD Patient (Predictive Value of Speckle Tracking Echocardiography )
ClinicalTrials.gov study NCT05790057. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Gut Microbiota and Modulation of Liver Damage in NAFLD
ClinicalTrials.gov study NCT02158351. IPD Sharing: Not stated. Countries: 1. Publications: 32.
Effect of VLCD on the Reduction of Liver Steatosis and Fibrosis in Subjects With Obesity and NAFLD
ClinicalTrials.gov study NCT04861571. IPD Sharing: NO. Countries: 1. Publications: 7.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.