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82 results for “PFAS”
PFAS and nitrate leaching from undisturbed soil columns receiving biosolids and mitigation potential of biochar
<p>Land application of biosolids recycles nutrients and reduces the need for commercial fertilizers. However, per- and polyfluoroalkyl substances (PFAS) may leach from biosolids, resulting in groundwater contamination. We measured PFAS leaching from land-applied biosolids through undisturbed soil column trials and evaluated the treatment potential of amending biosolids with biochar. Synthetic rainfall was applied weekly to undisturbed soil columns from four regions in Wisconsin, including two fields with a history of biosolids application, simulating annual precipitation. The treatments consisted of a control (soil only), soil amended with biosolids, and soil receiving a mixture of biosolids and biochar. Concentrations of total PFAS in leachate were significantly affected by soil location and site history, while only long chain PFAS concentrations were significantly affected by biosolids/biochar treatments. One-time application of biosolids may result in groundwater contamination, as PFAS concentrations in leachate exceeded the local groundwater standard (a combined perfluorooctanoic acid and perflourooctanesulfonic acid groundwater concentration of 20 ng L<sup>-1</sup>) at three locations. Legacy PFAS may pose a risk to human health years after biosolid application, as a control column from a site with an intensive history of biosolid application exceeded PFAS groundwater standards. Incorporation of biochar with biosolids during application mitigated PFAS (specifically from soils with elevated leaching potential) through significant reductions of C7 – C10 perfluoroalkyl carboxylic acids and C4, C6 – C8 perfluorosulfonic acids (40 to 64% reduction in measured Σ28 PFAS). Biochar may facilitate sustainable use of biosolids through mitigation of long-chain PFAS leaching, pending long-term field evaluation. </p>
Gene expression of PFAS exposed human liver spheroids and quality control
<p>Per- and polyfluoroalkyl substances (PFAS) are a wide range of chemicals that are used in a variety of consumer and industrial products leading to direct human exposure. Many PFAS are chemically non-reactive and persistent in the environment, resulting in additional exposure from water, soil, and dietary intake. While some PFAS have documented negative health effects, data on simultaneous exposures to multiple PFAS (PFAS mixtures) are inadequate for making informed decisions for risk assessment. The current study leverages data from previous work in our group using Templated Oligo-Sequencing (TempO-Seq™) for high-throughput transcriptomic analysis of PFAS-exposed primary human liver cell spheroids; herein, we determine the transcriptomic potency of PFAS in mixtures. Gene expression data from single PFAS and mixture exposures of liver cell spheroids were subject to benchmark concentration (BMC) analysis. We used the 25<sup>th</sup> lowest gene BMC as the point of departure to compare the potencies of single PFAS to PFAS mixtures of varying complexity and composure. Specifically, the empirical potency of eight PFAS mixtures were compared to predicted mixture potencies calculated using the principal of concentration addition (i.e., dose addition) in which mixture component potencies are summed by proportion to predict mixture potency. In this study, for most mixtures, empirical mixture potencies were comparable to potencies calculated through concentration addition. This work supports that the effects of PFAS mixtures on gene expression largely follow the concentration addition predicted response and suggests that effects of these individual PFAS in mixtures are not strongly synergistic or antagonistic.</p>
Deliverable D2.1 - Supplementary material : Datasets on the physicochemical properties of PFAS compounds
<p>Additional information on deliverable D2.1. Data sets for Machine Learning models on physicochemical properties of PFAS compounds for endpoints: logP (n-octanol/water), Sw (solubility in water), VP (vapor pressure), BCF (bioconcentration factor), MP (melting point) developped within the project H2020 PROMISCES. </p>
Dataset of concentrations of perfluoalkylated substances (PFAS) in tap an mineral waters in different parts of Spains and the World
<p>Dataset of concentrations of 20 PFAS in drinking water regulated according to Directive 2020/2184/EU.</p> <p>Data is provided in MS Excel (xlsx) and CSV formats and contains details on the concentrations of 20 PFAS in mineral (11 samples) and tap drinking water (23 samples from Spain and 12 samples from other countries) collected in 2022-2023. Concentrations are in ng/L.</p> <p><strong>Further details are provided in the associated publication:</strong></p> <p><em>J. López-Vázquez, R. Montes, R. Rodil, R. Cela, J.A. Martínez-Pontevedra, M.T. Pena, J.B. Quintana. Determination of regulated perfluoroalkyl substances (PFAS)<br>in drinking water according to Directive 2020/2184/EU.</em><em><br>Environmental Science and Pollution Research 2024, DOI: 10.1007/s11356-024-34852-z.<br><a href="https://doi.org/10.1007/s11356-024-34852-z" target="_blank" rel="noopener">https://doi.org/10.1007/s11356-024-34852-z</a><br></em></p> <div>The data is deposited in ZENODO:</div> <div><a href="../doi/10.5281/zenodo.10990801">https://zenodo.org/doi/10.5281/zenodo.10990801</a></div> <div> </div> <div><strong>If you reuse the data, please cite the publication and ZENODO deposit mentioned above</strong></div>
Outside the Safe Operating Space of a New Planetary Boundary for Per- and Polyfluoroalkyl Substances (PFAS)
<p>Supporting information (Open Data)m for the article Outside the Safe Operating Space of a New Planetary Boundary for Per- and Polyfluoroalkyl Substances (PFAS)</p>
Reply to PFAS restriction public consultation from ChemSec
<p>The pdf and excel file are what was submitted to the public consultation to the broad PFAS restriction by ChemSec. The excel is a database of alternatives to PFAS</p>
Reply to PFAS restriction public consultation from Stockholm University
<p>The response is from Stockholm University for the broad PFAS public consultation. The response shows alternatives for many PFAS functions.</p>
Assessing PFAS Exposure (APEX) for Better Health
ClinicalTrials.gov study NCT07391397. IPD Sharing: YES. Countries: 1. Publications: 17.
PFAS and nitrate leaching from undisturbed soil columns receiving biosolids and mitigation potential of biochar
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Gene expression of PFAS exposed human liver spheroids and quality control
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Pilot-Scale Continuous Foam Fractionation for the Removal of Per- and Polyfluoroalkyl Substances (PFAS) from Landfill Leachate
<p>This is the supplementary data for the publication '<span>Pilot-Scale Continuous Foam Fractionation for the Removal of Per- and Polyfluoroalkyl Substances (PFAS) from Landfill Leachate' (</span>https://pubs.acs.org/doi/full/10.1021/acsestwater.2c00032)</p>
Electrochemical Oxidation for Treatment of PFAS in Contaminated Water and Fractionated Foam─A Pilot-Scale Study
<p>This is the supplementary data to the publication '<span>Electrochemical Oxidation for Treatment of PFAS in Contaminated Water and Fractionated Foam─A Pilot-Scale Study' (<a title="DOI URL" href="https://doi.org/10.1021/acsestwater.2c00660">https://doi.org/10.1021/acsestwater.2c00660</a>). </span></p>
S9 | PFASTRIER | PFAS Suspect List: fluorinated substances
<p>This is the collection associated with list S9 PFASTRIER on the NORMAN Suspect List Exchange.</p> <p><a href="https://www.norman-network.com/nds/SLE/">https://www.norman-network.com/nds/SLE/</a></p> <p>S9 PFASTRIER <strong>PFAS Suspect List: fluorinated substances</strong></p> <p>Kindly supplied by Xenia Trier, David Lunderberg and colleagues.<br> Reference information contained in files.</p> <p>Nov 14 2019 update: added extra CSV for PubChem import. 12 March 2022 update: removed InChIKey duplicates and solvents from IK file.</p> <p> </p>
In-silico Mass Spectra for PFAS in the Blood Exposome Database
<p>In-silico spectra were generated for the PFAS compounds in the Blood Exposome Database using the ICEBERG model, re-trained using MONA/GNPS/NIST2020 spectra. </p>
In-silico Mass Spectra for PFAS compounds in Negative mode
<p>In-silico spectra were generated for PFAS compounds in negative mode, using the ICEBERG model, re-trained using MONA/GNPS/NIST2020 spectra.</p> <p>Disclaimer: These are simulated spectra so they should be used with cautions to annotate compounds in LC-HRMS datasets. </p>
PFAS Adsorption Using Viologen-Modified Covalent Organic Frameworks: Synergistic Adsorption Mechanisms Provide a Robust Approach for Water Purification
<p>Dataset for manuscript.</p>
PFAS degradation under UV irradiation
<p>Negative mode LC-ESI-MS/MS analysis of PFAS containing samples acquired in non-targeted DDA mode. Screening for degradation products of PFAS upon UV irradiation.</p>
ChemSec's PFAS Guide dataset
<p>ChemSec's PFAS Guide: PFAS chemicals are used in many product categories, even where you least expect it. The PFAS Guide can alert you to products likely to contain these chemicals and give your company advice on how to phase them out.</p> <p>More information and a user interface for this dataset is available at https://pfas.chemsec.org/</p>
Adapting a Mammography Decision Aid to Support Women Living in a Community Contaminated by PFAS
ClinicalTrials.gov study NCT06098118. IPD Sharing: YES. Countries: 1. Publications: 1.
Per and polyfluoroalkyl substances (PFAS) in marine and anadromous species sampled in the Southern Salish Sea
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.