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FIGURE 3. Fossil species Spinopinnophyllum acanthorachis S. Kumar, T in The earliest fossil evidence of spiny feather (pinnate-leaved) palms from the K-Pg of Gondwana
FIGURE 3. Fossil species Spinopinnophyllum acanthorachis S. Kumar, T. Su and M. A. Khan sp. nov. (SKBUH/PPL/ Um/L/48). (A) A palm leaf specimen showing a stout rachis with well-preserved spines (marked by white arrows) and well-separated plicate leaf segments; (scale bar = 1 cm); (B) A part of the fossil leaf specimen showing two prominent spines on the rachis (scale bar = 1 cm); (C) Counterpart of SKBUH/PPL/Um/L/48 (scale bar = 1 cm); (D, F, H, J) Enlarged views of S. acanthorachis leaf showing the different orientation of spines on the rachis; (E, G, I, K). Line drawing of (D, F, H, J) (scale bars = 1 cm).
FIGURE 2 in The earliest fossil evidence of spiny feather (pinnate-leaved) palms from the K-Pg of Gondwana
FIGURE 2. (A) Map showing Deccan Volcanic Province (DVP), red star showing fossil locality (modified after Smith et al., 2015); (B) Recovered spiny feather palms from surface exposures of Deccan sediments; (C) Palaeocontinental map showing the position of the surviving Indian plate and the fossil locality (red dot) at 65.5 Ma. Note that the now subducted 'Greater India' is not shown as its dimensions are poorly constrained, nor is the Tethyan Himalaya microterrane (base maps from https://www.odsn.de/odsn/services/paleomap/paleomap.html).
Single crystal diffraction images for a room temperature data collection on the LEF-PG co-crystal.
<p>A set of diffraction images collected on a Rigaku FRE+ diffractometer, equipped with HF Varimax confocal mirrors and an AFC12 goniometer and HG Saturn 724+ detector diffractometer.</p> <p>The sample is an organic co-crystal that forms part of a study of the LEF active pharmaceutical ingredient with a range of coformers. The structure with the PG coformer shows strong signs of modulation in the diffraction pattern and structure refinement. The model presented in the paper (submitted to Crystal Growth and Design) does not account for any modulation and serves the purpose of a suitable degree of characterisation precision for this article. </p> <p>The authors wish to make the raw data available so that those with interest and experise in handling modulated structures can perform more detailed modelling studies and/or use the data to test software or for training examples.</p>
Data from: A new Paleogene fossil and a new dataset for waterfowl (Aves: Anseriformes) clarify phylogeny, ecological evolution, and avian evolution at the K-Pg boundary
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Data from: The origin of the legumes is a complex paleopolyploid phylogenomic tangle closely associated with the Cretaceous-Paleogene (K-Pg) mass extinction event
The consequences of the Cretaceous-Paleogene (K-Pg) boundary (KPB) mass extinction for the evolution of plant diversity remain poorly understood, even though evolutionary turnover of plant lineages at the KPB is central to understanding assembly of the Cenozoic biota. The apparent concentration of whole genome duplication (WGD) events around the KPB may have played a role in survival and subsequent diversification of plant lineages. To gain new insights into the origins of Cenozoic biodiversity, we examine the origin and early evolution of the globally diverse legume family (Leguminosae or Fabaceae). Legumes are ecologically (co-)dominant across many vegetation types, and the fossil record suggests that they rose to such prominence after the KPB in parallel with several well-studied animal clades including Placentalia and Neoaves. Furthermore, multiple WGD events are hypothesized to have occurred early in legume evolution. Using a recently inferred phylogenomic framework, we investigate the placement of WGDs during early legume evolution using gene tree reconciliation methods, gene count data and phylogenetic supernetwork reconstruction. Using 20 fossil calibrations we estimate a revised timeline of legume evolution based on 36 nuclear genes selected as informative and evolving in an approximately clock-like fashion. To establish the timing of WGDs we also date duplication nodes in gene trees. Results suggest either a pan-legume WGD event on the stem lineage of the family, or an allopolyploid event involving (some of) the earliest lineages within the crown group, with additional nested WGDs subtending subfamilies Papilionoideae and Detarioideae. Gene tree reconciliation methods that do not account for allopolyploidy may be misleading in inferring an earlier WGD event at the time of divergence of the two parental lineages of the polyploid, suggesting that the allopolyploid scenario is more likely. We show that the crown age of the legumes dates to the Maastrichtian or early Paleocene and that, apart from the Detarioideae WGD, paleopolyploidy occurred close to the KPB. We conclude that the early evolution of the legumes followed a complex history, in which multiple auto- and/or allopolyploidy events coincided with rapid diversification and in association with the mass extinction event at the KPB, ultimately underpinning the evolutionary success of the Leguminosae in the Cenozoic.
FIG. 2 in Foraminiferal biostratigraphy, facies and sequence stratigraphy analysis across the K-Pg Boundary in Hazara, Lesser Himalayas (Dhudial Section)
FIG. 2. — Generalized stratigraphy of the study area (Shah 2009).
Molcular Dynamics Trajectories for GPR156 PG No Cholesterol
<p>Note the cholesterol between the dimers were not modelled in these trajectories. Obsolete.</p> <p> </p> <p>This is not the Molecular Dynamics Data for 10.1038/s41594-024-01224-7 for publication at</p> <p>Shin, J., Park, J., Jeong, J. <em>et al.</em> Constitutive activation mechanism of a class C GPCR. <em>Nat Struct Mol Biol</em> (2024). https://doi.org/10.1038/s41594-024-01224-7</p> <p>This folder contains the PDB format file ("Topology") and the XTC format file (Trajectories). The timestep in this strided trajectory is 0.5 ns per frame. Periodic boundary condition (pbc) can be restored using VMD's standard pbc commands.</p> <p>But please cite us if you still find this data useful!</p>
SUPER-G Citizen priorities and preferences for ES in relation to PG - survey results
<p><span>This data set consists of a large cross-country survey conducted for the EU funded project SuperG in 2020. It contains citizen perceptions of, and attitudes towards, rural management and attitudes towards ecosystem services. In addition, data regarding attitudes towards permanent grassland (in relation to cultural value, food productivity and supporting and regulating functions) are included. </span></p>
MD simulation of a model Gram-positive bilayer membrane (60% PG, 35% lysyl-PG, 5% CL)
<p><strong>Composition</strong>:</p> <p>Model bilayer composition aimed at replicating the behavior of the Staphylococcus aureus membrane (See also Mohanan et al. Chem Sci 2020, 11, 4669: <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159255/"><strong>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159255/</strong></a>)</p> <p>Per leaflet we have 48 POPG (16:0 / 18:1; -1 net charge), 28 DPPGK (16:0 / 16:0; +1 net charge), 4 TOCL1 (18:1,18:1 / 18:1,18:1; -1 net charge), giving 60% PG, 35% lysyl-PG, 5% CL. Bilayer is symmetric. </p> <p><strong>Technical details</strong>:</p> <p>OpenMM 7.5.1</p> <p>CHARMM36m force field</p> <p>6,712 TIP3P waters</p> <p>150 mM KCl (64 K+, 16 Cl-)</p> <p>Temperature = 303.15 K</p> <p>Trajectory output every 100 ps</p> <p>Trajectory length = 500 ns ( = 5,000 frames)</p> <p>(Standard CHARMM-GUI relaxation protocol)</p>
Efficacy and Safety of PG-530742 in the Treatment of Mild to Moderate Knee Osteoarthritis
ClinicalTrials.gov study NCT00041756. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Study of CGC-11047 (PG-11047) in Subjects With Advanced Refractory Solid Tumors
ClinicalTrials.gov study NCT00705653. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Post K-Pg rise in ant and termite prevalence underlies convergent dietary specialization in mammals
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A new notosuchian crocodyliform from the Paleocene of Patagonia and the survival of a large-bodied terrestrial lineage across the K–Pg mass extinction
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Data from: Genomic Signature of an Avian Lilliput Effect across the K-PG Extinction
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Data from: The origin of the legumes is a complex paleopolyploid phylogenomic tangle closely associated with the Cretaceous-Paleogene (K-Pg) mass extinction event
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Subspecies and Distribution. P. g. gymnocercus Fischer, 1814 — subtropical grasslands of NE Argentina, SE Brazil, Paraguay, and Uruguay. Pg. antiquus Ameghino, 1889 — Pampas grasslands, monte scrublands, and open woodlands of C Argentina. P. g. lordi Massoia, 1982 — Chaco-montane tropical forest ecotone in NW Argentina (Salta & Jujuy Provinces). The subspecific status of the Pampas Fox from Entre Rios Province in Argentina remains unclear, and there are no data regarding the taxonomic position of Bolivian foxes. in Canidae
Subspecies and Distribution. P. g. gymnocercus Fischer, 1814 — subtropical grasslands of NE Argentina, SE Brazil, Paraguay, and Uruguay. Pg. antiquus Ameghino, 1889 — Pampas grasslands, monte scrublands, and open woodlands of C Argentina. P. g. lordi Massoia, 1982 — Chaco-montane tropical forest ecotone in NW Argentina (Salta & Jujuy Provinces). The subspecific status of the Pampas Fox from Entre Rios Province in Argentina remains unclear, and there are no data regarding the taxonomic position of Bolivian foxes.
Supplementary material 1 from: Borges LM, Inglis PW, Simon MF, Ribeiro PG, de Queiroz LP (2022) Misleading fruits: The non-monophyly of Pseudopiptadenia and Pityrocarpa supports generic re-circumscriptions and a new genus within mimosoid legumes. In: Hughes CE, de Queiroz LP, Lewis GP (Eds) Advances in Legume Systematics 14. Classification of Caesalpinioideae Part 1: New generic delimitations. PhytoKeys 205: 239-259. https://doi.org/10.3897/phytokeys.205.82275
Voucher information and GenBank accession numbers (internal transcribed spacer-ITS sequences) for taxa used in this study
text-fig. 27. Posterior dorsal vertebrae of three theropod dinosaurs in left lateral view, showing states for several axial characters. A, Herrerasaurus ischigualastensis; penultimate dorsal vertebra; redrawn (reversed) from Novas (1993). B, Syntarsus rhodesiensis-, reconstruction of the eleventh dorsal vertebra; based on QG 1. c, unnamed compsognathine from the Lower Cretaceous of Brazil; reconstruction of the posteriormost dorsal vertebra; based on SMNK 2349 Pal. Abbreviations as in ext-figures 24 and 26, and: pg, pleurocentral groove; st, spine table. Scale bars represent 10 mm. in The interrelationships and evolution of basal theropod dinosaurs
text-fig. 27. Posterior dorsal vertebrae of three theropod dinosaurs in left lateral view, showing states for several axial characters. A, Herrerasaurus ischigualastensis; penultimate dorsal vertebra; redrawn (reversed) from Novas (1993). B, Syntarsus rhodesiensis-, reconstruction of the eleventh dorsal vertebra; based on QG 1. c, unnamed compsognathine from the Lower Cretaceous of Brazil; reconstruction of the posteriormost dorsal vertebra; based on SMNK 2349 Pal. Abbreviations as in ext-figures 24 and 26, and: pg, pleurocentral groove; st, spine table. Scale bars represent 10 mm.
PG-SGD Animations
<p>The two GIFs show a snapshot after each epoch of the Path-Guided Stochastic Gradient Descent (PG-SGD) algorithm which is described in https://github.com/pangenome/sorting-paper.<br> <br> `1D_PG-SGD.gif` shows the progression of the 1D algorithm of applied to a pangenome graph with 12 ALT sequences of the HLA-DRB1 gene from the GRCh38 reference genome. The layout and snapshots were created using `odgi sort` and each snapshot was visualized with `odgi viz`.</p> <p>`2D_PG-SGD.gif`shows the progression of the 2D algorithm of applied to a pangenome graph with 12 ALT sequences of the HLA-DRB1 gene from the GRCh38 reference genome. The layout and snapshots were created using `odgi layout` and each snapshot was visualized with `odgi draw`.</p>
Guselkumab in the Treatment of Adults With Pyoderma Gangrenosum (PG)
ClinicalTrials.gov study NCT06563323. IPD Sharing: NO. Countries: 1. Publications: 10.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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OpenNeuro
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