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152 results for “Peromyscus”
Fig. 3 in Peromyscus levipes (Rodentia: Cricetidae)
Fig. 3.—Geographic distribution of Peromyscus levipes. Subspecies are 1, P. l. ambiguus and 2, P. l. levipes. Map modified from Carleton (1989).
Fig. 2 in Peromyscus levipes (Rodentia: Cricetidae)
Fig. 2.—Dorsal, ventral, and lateral views of cranium and lateral view of mandible of an adult female Peromyscus levipes from Mexico (Escuela Nacional de Ciencias Biolo´ gicas, 27530). Greatest length of cranium is 27.2 mm. Photograph by Horacio Cabrera Santiago.
Fig. 1.—Adult male Peromyscus levipes from 7.9 in Peromyscus levipes (Rodentia: Cricetidae)
Fig. 1.—Adult male Peromyscus levipes from 7.9 km SW San Salvador el Seco (19u04933.60N and 97u41911.10W), Puebla, Mexico. Photograph by Noe´ Gonza´lez-Ruiz.
Respirometry data for cactus mice (Peromyscus eremicus) corresponding to Colella et al. 2021
<p>Metabolism is a complex phenotype shaped by natural environmental rhythms, as well as behavioral, morphological, and physiological adaptations. Metabolism has been historically studied under constant environmental conditions, but new methods of continuous metabolic phenotyping now offer a window into organismal responses to dynamic environments, and enable identification of abiotic controls and the timing of physiological responses relative to environmental change. We use indirect calorimetry to characterize metabolic phenotypes of the desert-adapted cactus mouse (<i>Peromyscus eremicus</i>) in response variable environmental conditions that mimic their native environment versus those recorded under constant warm and constant cool conditions, while using a constant photoperiod and full access to resources. We found significant sexual dimorphism, with males being more prone to dehydration than females. Under circadian environmental variation, most metabolic shifts occurred prior to physical environmental change and the timing was disrupted under both constant temperature-humidity treatments. The ratio of CO<sub>2</sub> produced to O<sub>2</sub> consumed (the respiratory quotient) reached greater than 1.0, only during the light phase under diurnally variable conditions, a pattern that strongly suggests that<i> </i>lipogenesis is contributing to the production of energy and endogenous water. Our results are consistent with historical descriptions of circadian torpor in this species (torpid by day, active by night), but reject the hypothesis that torpor is initiated by food restriction or negative water balance.</p>
Reproductive experience drives changes in behavior and physiology in male California mice (Peromyscus californicus)
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Microbiome diversity and zoonotic bacterial pathogen prevalence in Peromyscus mice from agricultural landscapes and synanthropic habitat
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Respirometry data for cactus mice (Peromyscus eremicus) corresponding to Colella et al. 2021
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The neural basis of species-specific defensive behaviour in Peromyscus mice
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Highland forest's environmental complexity drives landscape genomics and connectivity of the rodent Peromyscus melanotis
<p>We evaluate how the environmental complexity of La Malinche volcano influences patterns of genomic variation in <em>Peromyscus melanotis</em>, across two mountain slopes and global and regional geographic scales.Using reduced representation genomic sequencing we estimated population genetic diversity, subdivisions and migration rates. Remote sensing data and drone image processing were used to characterize landscape variables. We evaluated their effect on connectivity, based on a landscape analyses framework, using resistance surfaces, circuit theory and omnidirectional connectivity. Our findings showed how the forest environmental complexity across different geographic scales drives dispersal, genomic structure and connectivity patterns in this rodent, where dirt roads and disturbed areas limit its connectivity, while exhibiting higher connectivity at the highest elevations where the forest is less disturbed. Notably, that our 3D variable of tree height was significant demonstrates the utility in incorporating 3D vegetation structure variables into landscape genetic analyses.</p>
Data from: Mating system variation and gene expression in the male reproductive tract of Peromyscus mice
<p>Genes involved in reproduction often evolve rapidly at the sequence level due to postcopulatory sexual selection (PCSS) driven by male-male competition and male-female sexual conflict, but the impact of PCSS on gene expression has been under-explored. Further, though multiple tissues contribute to male reproductive success, most studies have focused on the testes. To explore the influence of mating system variation on reproductive tract gene expression in natural populations, we captured adult males from monogamous <em>Peromyscus californicus</em> and polygynandrous<em> P. boylii</em> and <em>P. maniculatus</em>. We generated RNAseq libraries, quantified gene expression in the testis, seminal vesicle, epididymis, and liver, and identified 3,627 mating system-associated differentially expressed genes (MS-DEGs), where expression shifted in the same direction in <em>P. maniculatus</em> and <em>P. boylii</em> relative to <em>P. californicus</em>. Gene expression variation was most strongly associated with mating behavior in the seminal vesicles, where 89% of differentially expressed genes were MS-DEGs, including key seminal fluid proteins <em>Svs2</em> and <em>Pate4</em>. We also used published rodent genomes to test for positive and relaxed selection on <em>Peromyscus</em>-expressed genes. Though we did not observe more overlap than expected by chance between MS-DEGs and positively selected genes, 203 MS-DEGs showed evidence of positive selection. Fourteen reproductive genes were under tree-wide positive selection but convergent relaxed selection in <em>P. californicus</em> and <em>Microtus ochrogaster</em>, a distantly related monogamous species. Changes in transcript abundance and gene sequence evolution in association with mating behavior suggest that male mice may respond to sexual selection intensity by altering aspects of sperm motility, sperm-egg binding, and copulatory plug formation.</p>
Data from: Characterization of a male reproductive transcriptome for Peromyscus eremicus (Cactus mouse)
Rodents of the genus Peromyscus have become increasingly utilized models for investigations into adaptive biology. This genus is particularly powerful for research linking genetics with adaptive physiology or behaviors, and recent research has capitalized on the unique opportunities afforded by the ecological diversity of these rodents. Well characterized genomic and transcriptomic data is intrinsic to explorations of the genetic architecture responsible for ecological adaptations. Therefore, this study characterizes the transcriptome of three male reproductive tissues (testes, epididymis and vas deferens) of Peromyscus eremicus (Cactus mouse), a desert specialist. The transcriptome assembly process was optimized in order to produce a high quality and substantially complete annotated transcriptome. This composite transcriptome was generated to characterize the expressed transcripts in the male reproductive tract of P. eremicus, which will serve as a crucial resource for future research investigating our hypothesis that the male Cactus mouse possesses an adaptive reproductive phenotype to mitigate water-loss from ejaculate. This study reports genes under positive selection in the male Cactus mouse reproductive transcriptome relative to transcriptomes from Peromyscus maniculatus (deer mouse) and Mus musculus. Thus, this study expands upon existing genetic research in this species, and we provide a high quality transcriptome to enable further explorations of our proposed hypothesis for male Cactus mouse reproductive adaptations to minimize seminal fluid loss.
Post-copulatory sexual selection is associated with sperm aggregate quality in Peromyscus mice
<p>In some species, sperm form coordinated groups that are hypothesized to improve their swimming performance in competitive contexts or to navigate through the viscous fluids of the female reproductive tract. Here we investigate sperm aggregation across closely-related species of <i>Peromyscus </i>mice that naturally vary by mating system to test the predictions that sperm aggregates (1) are faster than solitary sperm in species that females mate multiply to aid cells in sperm competition, and (2) outperform solitary sperm cells in viscous environments. We find significant variation in the size of sperm aggregates, which negatively associates with relative testis mass, a proxy for sperm competition risk, suggesting that post-copulatory sexual selection has a stabilizing effect on sperm group size. Moreover, our results show that sperm aggregates are faster than solitary sperm in some, but not all, species, and this can vary by fluid viscosity. Of the two species that produce the largest and most frequent groups, we find that sperm aggregates from the promiscuous <i>P. maniculatus</i> are faster than solitary sperm in every experimentally viscous environment but aggregation provides no such kinematic advantage under these same conditions for the monogamous <i>P. polionotus</i>. The reduced performance of <i>P. polionotus</i> aggregates is associated with less efficient aggregate geometry and the inclusion of immotile or morphological abnormal sperm. Our cross-species comparison yields insight into the evolution of sperm social behaviors, provides evidence of extensive variation in the <i>Peromyscus</i> lineage, and reveals that differences in sperm aggregate quality associate with post-copulatory sexual selection.</p>
Transcriptome of Peromyscus leucopus lungs infected with SARS-CoV-2
<p><em>Peromyscus leucopus</em> is a reservoir for numerous zoonoses and one of the most abundant mammals in North America. Since they live near humans we are interested in the possibility of SARS-CoV-2 infection in this animal model from a zoonoses standpoint. The experimental design for the first trial involves using adult male and female <em>P. leucopus</em> LL stock. Animals were dosed with nasal inhalation of either tissue culture medium (DMEM) alone (controls) or alpha variant, WA1 strain of SARS-CoV-2 virus. We dosed 8 animals with a virus (titer 2x104) and 6 with DMEM alone. Animals were euthanized at either 3 or 6 days post-infection. For a second trial, <em>P. leucopus</em> animals were 1-3 years old and we had 3 groups: control animals with nasal inhalation of media, control animals with nasal inhalation of the heat-treated virus, and infected animals. Each group has 4 animals euthanized on 3- or 6-days post-infection (DPI). Lung tissue was used for RNA isolation and further sequencing to obtain 40 x 106 PE150 reads.</p>
Data from: Characterization of a male reproductive transcriptome for Peromyscus eremicus (Cactus mouse)
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Transcriptome of Peromyscus leucopus lungs infected with SARS-CoV-2
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Data from: Mating system variation and gene expression in the male reproductive tract of Peromyscus mice
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Effects of X-ray irradiation and housing conditions on mitochondria in Peromyscus maniculatus
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Post-copulatory sexual selection is associated with sperm aggregate quality in Peromyscus mice
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Microscopy images from: A physiological and histological atlas of reproduction in the North American deer mouse (Peromyscus maniculatus)
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Untargeted metabolomics molecular features data for plasma of 20 Peromyscus leucopus and 20 Mus musculus treated with LPS or controls
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
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