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ShareScore release 0.9.0
Dataset results
32 results for “Persistent Organic Pollutants”
Persistent Organic Pollutants and Mechanical Discharge: Limiting the Impact of Bariatric Surgery Through Personalized Adapted Physical Activity
ClinicalTrials.gov study NCT06597617. IPD Sharing: NO. Countries: 1. Publications: 0.
Effects of Combined Persistant Organic Pollutants on Global Gene Expression in Human HepaRG Cells
GEO Series GSE46874. Homo sapiens. 12 samples. Type: Expression profiling by array.
Calcium signaling as a possible mechanism behind increased locomotor response in zebrafish larvae exposed to a human relevant persistent organic pollutant mixture or PFOS
GEO Series GSE144525. Danio rerio. 20 samples. Type: Expression profiling by high throughput sequencing.
Persistent Organic Pollutants cause insulin resistance and ruin the health effects of salmon oil
GEO Series GSE13716. Rattus norvegicus. 5 samples. Type: Expression profiling by array.
Effetcs of several families of persistent organic pollutants on the undifferentiated and adipocyte differentiated human Multipotent Adipose-Derived Stem (hMADS) cells
GEO Series GSE32026. Homo sapiens. 24 samples. Type: Expression profiling by array.
Persistant Organics Pollutants in Breast Cancer.
ClinicalTrials.gov study NCT03788187. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Persistent organic pollutants alter DNA methylation during human adipocyte differentiation
GEO Series GSE75133. Homo sapiens. 15 samples. Type: Methylation profiling by genome tiling array.
Microbiota dysbiosis associated with type 2 diabetes-like effects caused by chronic exposure to a mixture of chlorinated persistent organic pollutants in zebrafish [I]
GEO Series GSE233631. Danio rerio. 4 samples. Type: Expression profiling by high throughput sequencing.
Microbiota dysbiosis associated with type 2 diabetes-like effects caused by chronic exposure to a mixture of chlorinated persistent organic pollutants in zebrafish
GEO Series GSE233633. Danio rerio. 33 samples. Type: Expression profiling by high throughput sequencing; Other.
Transcriptomic analysis of adult zebrafish brain exposed developmentally to 2 concentrations of a persistent organic pollutants (POP) mixture or 2 concentrations of PFOS (0.3, 2.06 mg/L)
GEO Series GSE162503. Danio rerio. 80 samples. Type: Expression profiling by high throughput sequencing.
Microbiota dysbiosis associated with type 2 diabetes-like effects caused by chronic exposure to a mixture of chlorinated persistent organic pollutants in zebrafish [II]
GEO Series GSE233632. Danio rerio. 29 samples. Type: Other.
Dataset associated with the paper "Thyroid Cancer and Endocrine Disruptive Chemicals: A Case-Control Study on Per-fluoroalkyl Substances (PFAS) and Other Persistent Organic Pollutants (POPs)"
<h2>Abstract</h2> <div> <p><strong>Objective: </strong>To evaluate the possible association between some endocrine disruptive chemicals and thyroid cancer (TC) in an Italian case-control cohort.</p> <p><strong>Methods: </strong>We enrolled 112 TC patients and 112 sex- and age-matched controls without known thyroid diseases. Per- and poly-fluoroalkyl substances (PFAS), poly-chlorinated biphenyls (PCBs), and dichlorodiphenyltrichloroethane (4,4'-DDT, and 4,4'-DDE) were measured in the serum by liquid or gas chromatography-mass spectrometry. Unconditional logistic regression, Bayesan Kernel Machine Regression and Weighted Quantile Sum models were used to estimate the association between TC and pollutants' levels, considered individually or as mixture. BRAFV600E mutation was assessed by standard methods.</p> <p><strong>Results: </strong>The detection of perfluorodecanoic acid (PFDA) was positively correlated to TC (OR= 2.03, 95% CI 1.10-3.75, p=0.02), while a negative association was found with perfluorohexanesulfonic acid (PFHxS) levels (OR=0.63, 95% CI 0.41-0.98, p=0.04). Moreover, perfluorononanoic acid (PFNA) was positively associated with the presence of thyroiditis, while PFHxS and perfluorooctane sulfonic acid (PFOS) with higher levels of pre-surgical Thyroid-Stimulating Hormone (TSH). PFHxS, PFOS, PFNA and PFDA were correlated with less aggressive TC, while poly-chlorinated biphenyls (PCB-105 and PCB-118) with larger and more aggressive tumours. Statistical models showed a negative association between pollutants' mixture and TC. BRAFV600E mutations resulted associated with PCB-153, PCB-138 and PCB-180.</p> <p><strong>Conclusions: </strong>Our study suggests, for the first time in a case-control population, that exposure to some PFAS and PCBs associates with TC and some clinical and molecular features. On the contrary, an inverse correlation was found with both PFHxS and pollutants' mixture, likely due to a potential reverse causality.</p> <p> </p> <p>Dataset associated with the paper "Thyroid Cancer and Endocrine Disruptive Chemicals: A Case-Control Study on Per-fluoroalkyl Substances (PFAS) and Other Persistent Organic Pollutants (POPs)".</p> <p>This set of raw data cannot be publicly available as including sensitive information, but might be made available to interested researchers upon reasonable request. Please, forward you request to l.fugazzola@auxologico.it</p> </div>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.