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214 results for “Preclinical models”

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geo24/100

Impact of Maternal Immune Activation and Sex on Placental and Fetal Brain Cytokine and Gene Expression Profiles in a Preclinical Model of Neurodevelopmental Disorders

GEO Series GSE248222. Mus musculus. 64 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2024View details →
geo24/100

A first-in-class, humanized antibody targeting alternatively spliced tissue factor: preclinical evaluation in an orthotopic model of pancreatic ductal adenocarcinoma

GEO Series GSE158847. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2020View details →
geo24/100

CDK12/13 inactivation triggers STING-mediated antitumor immunity in preclinical models [RNA-seq]

GEO Series GSE283088. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2025View details →
geo24/100

An in vivo avian paradigm to model human melanoma disease and perform fast and relevant preclinical studies

GEO Series GSE206689. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2022View details →
geo24/100

Inhibition of CXCL10 and IFN-γ ameliorates myocarditis in preclinical models of SARS-CoV- 2 mRNA vaccination

GEO Series GSE254537. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2025View details →
geo24/100

Highly selective HSP90 inhibitor, pimitespib, demonstrates its potent growth suppressive activity to adult T-cell leukemia in preclinical models (Su9T01).

GEO Series GSE168558. Homo sapiens. 6 samples. Type: Expression profiling by array.

openGEO-OpenFeb 2022View details →
geo24/100

Zongertinib (BI01810631), an irreversible HER2 TKI, spares EGFR signaling and improves therapeutic response in preclinical models and patients with HER2-driven cancers

GEO Series GSE252799. Homo sapiens. 90 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2024View details →
geo24/100

Inflammasome signaling is dispensable for ß-amyloid-induced neuropathology in preclinical models of Alzheimer's disease

GEO Series GSE249611. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2024View details →
geo24/100

Antitumor Activity of the Novel Flavonoid Oncamex in Preclinical Breast Cancer Models

GEO Series GSE70949. Homo sapiens. 10 samples. Type: Expression profiling by array.

openGEO-OpenSep 2015View details →
geo24/100

Rational selection of syngeneic preclinical tumor models for immunotherapeutic drug discovery

GEO Series GSE85509. Mus musculus. 299 samples. Type: Expression profiling by array; Genome variation profiling by genome tiling array.

openGEO-OpenDec 2016View details →
geo24/100

Intratumoral administration of lipid nanoparticles carrying mRNA encoding for IL-21, IL-7, and 4-1BBL induces anti-tumor immunity in preclinical tumor models.

GEO Series GSE249674. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2024View details →
geo24/100

Glycaemic variability identified as a critical determinant of myocyte dysfunction and risk for myocardial injury in preclinical models of diabetes

GEO Series GSE279917. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2025View details →
geo24/100

Analysis of the brain metastasis-associated microenvironment in different preclinical models of brain metastasis

GEO Series GSE231646. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2023View details →
geo24/100

CRISPR repair in a preclinical model of Noonan syndrome associated cardiomyopathy II

GEO Series GSE145349. Homo sapiens. 11 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2020View details →
geo24/100

A novel preclinical mouse model of spontaneous breast cancer metastasis

GEO Series GSE34666. Mus musculus. 35 samples. Type: Genome variation profiling by genome tiling array.

openGEO-OpenDec 2011View details →
geo24/100

Targeting SUMOylation triggers interferon-beta-dependent activation of patient and allogenic Natural Killer cells in preclinical models of Acute Myeloid Leukemia [CUT&RUN]

GEO Series GSE285061. Homo sapiens. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJun 2025View details →
geo24/100

Occult polyclonality of preclinical pancreatic cancer models drives in vitro evolution.

GEO Series GSE173339. Homo sapiens. 13 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenApr 2022View details →
geo24/100

MRTX1719 is an MTA-cooperative PRMT5 inhibitor that exhibits synthetic lethality in preclinical models and patients with MTAP deleted cancer

GEO Series GSE240145. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2023View details →
geo24/100

Preclinical evaluation of the efficacy of anti-human SIRPα antibody for cancer immunotherapy using the MITRG humanized mouse model

GEO Series GSE239693. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2023View details →
geo24/100

A novel irreversible TEAD inhibitor, SWTX-143, blocks the Hippo pathway and causes tumor regression in preclinical mesothelioma models [SubQ]

GEO Series GSE222962. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2023View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record