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Dataset results
484 results for “T cell exhaustion”
Blockade of LAG3 and PD1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity
<p>This is the data necessary to reproduce the figures from "<em>Blockade of LAG3 and PD1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity</em>" by Cillo et al.</p>
Pembrolizumab Effects on NK Cell Exhaustion in Melanoma (Merck NK-IIT)
ClinicalTrials.gov study NCT03241927. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Dasatinib enhances anti-tumor efficacy of chimeric antigen receptor T cells by inhibiting cell differentiation and exhaustion
GEO Series GSE151774. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
The β1-adrenergic receptor links sympathetic nerves to T cell exhaustion
GEO Series GSE213607. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
RELB Reprograms Exhausted Tumor-Infiltrating Lymphocytes for Improved Adoptive Cell Therapy [TCR-Seq]
GEO Series GSE303438. Homo sapiens. 38 samples. Type: Other.
Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8 T cells [dataset 1]
GEO Series GSE272993. Homo sapiens. 360 samples. Type: Expression profiling by high throughput sequencing; Other.
Deletion of a state-specific PD-1 enhancer modulates exhausted T cell fate and function [RNA-Seq]
GEO Series GSE269580. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Divergent clonal differentiation trajectories of T cell exhaustion (scATAC-seq)
GEO Series GSE188669. Mus musculus. 11 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Transcriptional landscape of four exhausted CD8 T cell subsets
GEO Series GSE149876. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
HMGB2 regulates the differentiation and stemness of exhausted CD8+ T cells during chronic viral infection and cancer [RNA-seq]
GEO Series GSE237812. Mus musculus. 17 samples. Type: Expression profiling by high throughput sequencing.
ID2 and HIF-1α Collaborate to Protect Quiescent Hematopoietic Stem Cells from Activation, Differentiation and Exhaustion
GEO Series GSE198599. Mus musculus; Mus. 6 samples. Type: Expression profiling by high throughput sequencing.
Orthogonal Gene Engineering Enables Novel Synthetic States of Powerful Tumor-rejecting CD8+ T Cells Escaping Canonical Exhaustion
GEO Series GSE200535. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Reversible mitochondrial dysfunction drives terminal T-cell exhaustion
GEO Series GSE138459. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8 T cells [dataset 2]
GEO Series GSE272734. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing.
Altered costimulatory signaling and hypoxia support chromatin landscapes that limit the functional potential of exhausted T cells in cancer [RNA-seq]
GEO Series GSE175408. Mus musculus. 40 samples. Type: Expression profiling by high throughput sequencing.
STAT5-activating oncogenes drive Oncostatin M production causing T cell exhaustion and suppressive myeloid cell recruitment
GEO Series GSE280685. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
BTLA contributes to acute-on-chronic liver failure infection and mortality through CD4+ T-cell exhaustion
GEO Series GSE248217. Homo sapiens. 22 samples. Type: Expression profiling by high throughput sequencing.
Single-Cell Transcriptomics Matrix of all PBMC samples used in “Single-Cell Transcriptomics Reveals Immune Dysregulation in HIV-MTB Co-Infection: CD4+ T Cells Exhaustion and CD8+ T Cells Hyperactivati
GEO Series GSE293960. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Human Immune Exhaustion Gene Expression Profile in C7R-CAR and CAR NK cells
GEO Series GSE277499. Homo sapiens. 6 samples. Type: Other.
PGE2 effect on unstimulated and exhausted human CD8+ T-cells
GEO Series GSE227316. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.