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454 results for “Tau”

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zenodo40/100

DF Tau: 1.3mm ALMA observations of the young binary DF Tau

<p>The <strong>self-calibrated ALMA observations at 1.3mm wavelengths of the young binary system DF Tau</strong>, published in <strong>Grant et al., (2024)</strong>. These observations are separated by epoch, and classified with the sufix LB or SB for "Long Baselines" and "Short Baselines". SB1 and LB1 are the observations from ALMA project ID:2019.1.01739.S (PI: Tofflemire, Benjamin), while SB2 and LB2 are from ALMA Project ID:2021.1.00854.S (PI: Long, Feng).&nbsp;</p>

opencc-by-4.0Jun 2024View details →
zenodo40/100

Triple-resonance NMR spectra of Tau 1-239 protein fragment acquired at 5 C, 10 C and 15 C

<p>Dataset used in a paper "Using temperature coefficients to support resonance<br>assignment of intrinsically disordered proteins" by Paulina Putko, Javier Agustin Romero, Christian F. Pantoja, Markus<br>Zweckstetter, Krzysztof Kazimierczuk, and Anna Zawadzka-Kazimierczuk</p> <p>The following spectra have been collected:</p> <table> <tbody> <tr> <td>Experiments<br>T : 5 C</td> <td>NUS points<br>(Recorded)</td> <td>NS (scans)<br>(Recorded)</td> </tr> <tr> <td>HNCO</td> <td>600</td> <td>4</td> </tr> <tr> <td>HN(CA)CO</td> <td>1000</td> <td>16</td> </tr> <tr> <td>HNCA</td> <td>600</td> <td>8</td> </tr> <tr> <td>HN(CO)CA</td> <td>450</td> <td>8</td> </tr> <tr> <td> <p>CBCA(CO)NH</p> <p>(HAHB)CBCA(CO)NH</p> </td> <td>1000</td> <td>&nbsp;</td> </tr> <tr> <td>Experiments<br>T : 10 C</td> <td>NUS points<br>(Recorded)</td> <td>NS (scans)<br>(Recorded)</td> </tr> <tr> <td>HNCO</td> <td>600</td> <td>4</td> </tr> <tr> <td>HN(CO)CA</td> <td>450</td> <td>8</td> </tr> <tr> <td>(HAHB)CBCA(CO)NH</td> <td>1000</td> <td>8</td> </tr> <tr> <td>Experiments<br>T : 15 C</td> <td>NUS points<br>(Recorded)</td> <td>NS (scans)<br>(Recorded)</td> </tr> <tr> <td>HNCO</td> <td>&nbsp;600</td> <td>&nbsp;4</td> </tr> <tr> <td>HN(CO)CA</td> <td>&nbsp;450</td> <td>&nbsp;8</td> </tr> <tr> <td>(HAHB)CBCA(CO)NH</td> <td>&nbsp;1000</td> <td>&nbsp;8</td> </tr> <tr> <td>&nbsp;</td> <td>&nbsp;</td> <td>&nbsp;</td> </tr> </tbody> </table>

opencc-by-4.0Jun 2024View details →
zenodo40/100

Fig. 1 in First report of economic injury to tomato due to Zeugodacus tau (Diptera: Tephritidae): relative abundance and effects of cultivar and season on injury

Fig. 1. Seasonal pattern of Zeugodacus tau male adults (mean ± SE) captured by Cue-lure-based traps in tomato in (a) season 1, and (b) season 2.

opencc-by-4.0Mar 2017View details →
zenodo40/100

FIG. 10 in Pigs and ritual-hunting among the highland Tau-Buhid in Mounts Iglit-Baco natural park, Philippines

FIG. 10. — Men from middle and highland regions waiting for the rain to pour down. The man on the left (wearing a shirt) may witness the process but cannot join directly in the activity because he is from the middle region (near Mount Iglit). As of this writing, only secluded highland communities may join in burning the sagrado (sacred place). Photo credits: C. A. Rosales.

opencc-by-4.0Jun 2021View details →
zenodo40/100

FIG. 2 in Pigs and ritual-hunting among the highland Tau-Buhid in Mounts Iglit-Baco natural park, Philippines

FIG. 2. — Black swine believed to have turned feral near Mount Iglit (Buksol Mangibok for the Tau-Buhid). Photo credits: C. A. Rosales.

opencc-by-4.0Jun 2021View details →
zenodo40/100

FIG. 8 in Pigs and ritual-hunting among the highland Tau-Buhid in Mounts Iglit-Baco natural park, Philippines

FIG. 8. — Author (upper left) in conversation with fufuama (grandfather, elder) Butodaol (wearing G-string,his back to the camera) through an interpreter (wearing colored shorts, middle), a few days before the safong (circular burning). The boy (lower left) is Butodaol's attendant, while the man on the upper right is a park ranger and one of the author's casual informants. Butodaol fears that the State might totally prohibit their hunting activities because of stricter law enforcement in the protected area. He could not imagine that younger generations might be forced to abandon the highlands to the lowlands, as is gradually happening now in fear of being apprehended by the law. Photo credits: C. A. Rosales.

opencc-by-4.0Jun 2021View details →
zenodo40/100

FIG. 4 in Pigs and ritual-hunting among the highland Tau-Buhid in Mounts Iglit-Baco natural park, Philippines

FIG. 4. — Moon phases, sunrise, animal-forming spirits transformation, and casting of spells. Credits: C. A. Rosales.

opencc-by-4.0Jun 2021View details →
zenodo40/100

FIG. 5 in Pigs and ritual-hunting among the highland Tau-Buhid in Mounts Iglit-Baco natural park, Philippines

FIG. 5. — Customary marker indicating distance and number of balatik (speartrapping) near the trail. Each arrow represents a spear-trap and its distance from the trail. When the arrow points a little upward, it means the trap is far from the trail. Photo credits: C. A. Rosales.

opencc-by-4.0Jun 2021View details →
zenodo40/100

FIG. 6 in Pigs and ritual-hunting among the highland Tau-Buhid in Mounts Iglit-Baco natural park, Philippines

FIG. 6. — Sagrado (sacred place) at the foot of Mount Talafu, east (right) and west (left). Photo credits: C. A. Rosales.

opencc-by-4.0Jun 2021View details →
zenodo40/100

FIG. 3 in Pigs and ritual-hunting among the highland Tau-Buhid in Mounts Iglit-Baco natural park, Philippines

FIG. 3. — Siganon (lowlanders) swine traders who supply pork in the local market and occasionally exchange pigs for swidden-grown rice with highlanders. Photo credits: C. A. Rosales.

opencc-by-4.0Jun 2021View details →
zenodo40/100

FIG. 1. — This concrete bridge replaced a in Pigs and ritual-hunting among the highland Tau-Buhid in Mounts Iglit-Baco natural park, Philippines

FIG. 1. — This concrete bridge replaced a hanging bridge as part of the State modernization plan for the Mounts Iglit-Baco Natural Park. For many Tau-Buhid, the concrete bridge represents a denial of their legal and customary rights within and over the extent of their lands, and is a threat to the survival of their way of life. Through this bridge, State surveillance and control of highland activities intensified. Photo credits: C. A. Rosales.

opencc-by-4.0Jun 2021View details →
zenodo40/100

FIG. 7 in Pigs and ritual-hunting among the highland Tau-Buhid in Mounts Iglit-Baco natural park, Philippines

FIG. 7. — Fufuama (grandfather, elder) Butodaol, leader of the highland TauBuhid. Photo credits: C. A. Rosales.

opencc-by-4.0Jun 2021View details →
zenodo40/100

Figure 5. A in Geometric morphometric and molecular evidence suggest a new fruit fly species in Bactrocera (Zeugodacus) tau complex (Diptera: Tephritidae)

Figure 5. A Bayesian phylogenetic tree (COI sequence, 580 bp) generated with the generalized time reversible model. Labels at branch ends are species and group names. Numbers at nodes represent the posterior possibilities that supported by sequences.

opencc-by-4.0Dec 2018View details →
zenodo40/100

Figure 3 in Geometric morphometric and molecular evidence suggest a new fruit fly species in Bactrocera (Zeugodacus) tau complex (Diptera: Tephritidae)

Figure 3. Discrimination of wing shape in four groups projected by CVs. Each polygon defines the outermost individuals in each group. A. Male. B. Female.

opencc-by-4.0Dec 2018View details →
zenodo40/100

Figure 4 in Geometric morphometric and molecular evidence suggest a new fruit fly species in Bactrocera (Zeugodacus) tau complex (Diptera: Tephritidae)

Figure 4. Gr.I and Gr.II discrimination by aculeus outlines. A distribution of samples on the best CV–x axis, in which the y axis shows the number of individuals in each interval. An inset displays a superimposition of aculeus shapes.

opencc-by-4.0Dec 2018View details →
zenodo40/100

Figure 1 in Geometric morphometric and molecular evidence suggest a new fruit fly species in Bactrocera (Zeugodacus) tau complex (Diptera: Tephritidae)

Figure 1. Criteria of sample classification. A. A medial vitta of Gr.I, characterized by a plain yellow band with posterior expansion. B. A medial vitta pattern of Gr.II, characterized by a yellow band inserted with a black strip in presutural region, and posteriorly constricted. Scale bar = 1 mm.

opencc-by-4.0Dec 2018View details →
zenodo40/100

Figure 2 in Geometric morphometric and molecular evidence suggest a new fruit fly species in Bactrocera (Zeugodacus) tau complex (Diptera: Tephritidae)

Figure 2. Landmark design for wing and aculeus GM analyses. A. Type 1 landmarks on wing venation labeled with downward arrows and numbers indicating locations in geometric analysis. B. A trilobed aculeus. C. A yellow line representing the alignment of pseudolandmarks along an outline of aculeus tip, from one lateral apex to another lateral. Scale bars: A = 1 mm; B = 50 μm.

opencc-by-4.0Dec 2018View details →
dryad40/100

Single-synapse analyses of Alzheimer's disease implicate pathologic tau, DJ1, CD47, and ApoE

<p>Synaptic molecular characterization is limited for Alzheimer's disease (AD). Our newly invented mass cytometry-based method, Synaptometry by Time of Flight (SynTOF), was used to measure 38 antibody probes in approximately 17 million single-synapse events from human brains without pathologic change or with pure AD or Lewy body disease (LBD), non-human primates (NHP), and PS/APP mice. Synaptic molecular integrity in humans and NHP was similar. Although not detected in human synapses, Aβ was in PS/APP mice single-synapse events. Clustering and pattern identification of human synapses showed expected disease-specific differences, like increased hippocampal pathologic tau in AD and reduced caudate dopamine transporter in LBD, and revealed novel findings including increased hippocampal CD47 and lowered DJ1 in AD and higher ApoE in AD with dementia. Our results were independently supported by multiplex ion beam imaging of intact tissue. This highlights the higher depth and breadth of insight on neurodegenerative diseases obtainable through SynTOF.</p>

opencc-zeroSep 2021View details →
zenodo40/100

Network of hotspot interactions cluster tau amyloid folds

<p>Datafiles associated with <strong>Network of hotspot interactions cluster tau amyloid folds.</strong></p> <p>&nbsp;</p> <p>The alascan files contain the averaged and raw outputs of the <em>in silico </em>alanine scan conducted on tau fibrils. The combo aggregation file contains ThT fluorescence data from the VQIVYK/VEVKSE alanine mutants and coaggregation experiments. The incorporation_vs_insilico file contains the results of the alanine scan top and bottom hits compared to the results of the incorporation experiment of alanine mutants on that position.</p> <p>&nbsp;</p> <p>Version 2: Files added providing data for how edge and center chains contribute to the total energetics, as well as a per-layer energy contribution to total deltaREU in the alanine scan of the PHF fibril.</p>

opencc-by-4.0Jun 2022View details →
zenodo40/100

Synaptic oligomeric tau in Alzheimer's disease – a potential culprit in the spread of tau pathology through the brain

<p>In Alzheimer&rsquo;s disease (AD), fibrillar tau pathology accumulates and spreads through the brain and synapses are lost. Evidence from mouse models indicates that tau spreads trans-synaptically from pre- to postsynapses and that oligomeric tau is synaptotoxic, but data on synaptic tau in human brain is scarce. Here we used sub-diffraction-limit microscopy to study synaptic tau accumulation in post-mortem temporal and occipital cortices of human AD and control donors. Oligomeric tau is present in both pre- and postsynaptic terminals even in areas without abundant fibrillar tau deposition. Further, there is a higher proportion of oligomeric tau compared to phosphorylated or misfolded tau found at synaptic terminals. These data suggest that accumulation of oligomeric tau in synapses is an early event in disease pathogenesis, and that tau pathology may progress through the brain via trans-synaptic spread in human disease. Thus, specifically reducing oligomeric tau at synapses may be a promising therapeutic strategy for AD.</p>

opencc-by-4.0Mar 2023View details →

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Last verified 2026-04-29Open record