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257 results for “Triglycerides”
Body mass and triglycerides predict departure of free-living nomadic pine siskins
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A gene variation at the ZPR1 locus (rs964184) interacts with the type of diet to modulate postprandial triglycerides in patients with coronary artery disease: From the Cordioprev Study
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Tests of Martini3 coarse-grained triglycerides
<p>LTF: Initial tests of Martini coarse-grained triglycerides triolein and trimyristin together with atomistic reference simulations</p>
Supplement material from: Plasma levels of triglycerides and IL6 are associated with weight regain and fat mass expansion
<p><strong>Background/Objective:</strong> Long-term weight loss (WL) maintenance is the biggest challenge for overweight and obesity due to the almost unavoidable phenomenon of partial or even total weight regain (WR) after WL. In the current study we investigated the relations of (the changes of) adipocyte size and other risk biomarkers with WR during the follow up of the Yoyo dietary intervention.</p> <p><strong>Design:</strong> In this randomized controlled study, 48 overweight/obese participants underwent a (very) low calorie diet to lose weight, followed by a weight stable period of 4 weeks and a follow-up period of 9 months. Anthropometric measurements, adipocyte volume of abdominal subcutaneous adipose tissue and plasma metabolic parameters (FFA, TG, total cholesterol, glucose, insulin, HOMA-IR, IL6, ACE activity, RBP4) at the beginning and the end of the follow-up were analyzed.</p> <p><strong>Results:</strong> Our results show that changes of TG, IL6, HOMA-IR and ACE are significantly positively correlated with WR. Multiple linear regression analysis shows that only the changes of TG and IL6 remained significantly correlated with WR and increased body fat mass. Moreover, the change of HOMA-IR was tightly correlated with the change in TG. Surprisingly, the change of adipocyte volume during follow up was not correlated with WR nor with other factors, but positive correlations between adipocyte volume and HOMA-IR were found at the beginning and end of the follow up.</p> <p><strong>Conclusions: </strong>These results suggest that TG and IL6 are independently linked to WR via separate mechanisms, and that HOMA-IR and adipocyte volume may indirectly link to WR through the change of plasma TG.</p>
Unfavorable triglyceride-rich particle profile in subclinical thyroid disease: A cross-sectional analysis of ELSA-Brasil
<p><span>Introduction: Subclinical thyroid disorders have been associated with atherosclerosis and increased cardiovascular risk. As triglyceride-rich lipoprotein particles (TRLP) have recently emerged as a casual factor for atherogenesis, the aim of this study was to evaluate the relationship between subclinical hypo and hyperthyroidism and TRLP subfractions.</span></p> <p><span>Methods: We selected 5,066 participants from the ELSA-Brasil cohort with available data of thyroid function and lipid profile measured by NMR. Individuals were divided into three groups by baseline thyroid function (subclinical hypothyroidism, euthyroidism, and subclinical hyperthyroidism). TRLP subfractions were analyzed through Nuclear Magnetic Resonance (NMR) spectroscopy. To examine the association between TRLP subfractions and thyroid function, we conducted univariate and multivariate linear regression models adjusted for demographic characteristics, BMI, diabetes, smoking status and alcohol use.</span></p> <p><span>Results: Of 3,304 individuals, 54% were women, with a mean age of 50.6±8,7 years, 51% white and 53% with at least college education. Of these individuals, 92% were euthyroid, whereas 6.8% had subclinical hypothyroidism and 1.2% had subclinical hyperthyroidism. The univariate linear regression showed that Very Small TRLP (p=0.026) and Very Large TRLP (p=0.008) were statistically increased in subclinical hypothyroidism when compared to euthyroidism. In subclinical hyperthyroidism, there was a reduction in total TRLP (p=0.003), seemingly driven by reduced Very Small-TRLP (p=0.067). The findings were confirmed when adjusted for demographic characteristics, as well as comorbidities.</span></p> <p>Conclusions: This study suggests that subclinical hypothyroidism is associated to very small and very large TRLP, which are related to an unfavorable atherogenic profile. Subclinical hyperthyroidism is associated to lower very small TRLP.</p>
Acute Effect of Intensive Insulin Infusion on Intestinal Triglyceride-rich-lipoprotein-apoB48 Metabolism in Type 2 Diabetic Patients
ClinicalTrials.gov study NCT00950209. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effect of Therapeutic Phlebotomies on the Triglycerides Concentration in Patients With Hypertriglyceridemia and Hyperferritinemia
ClinicalTrials.gov study NCT02526121. IPD Sharing: YES. Countries: 1. Publications: 1.
Prognostic Impact of an Oral Triglyceride Tolerance Test in Patients After Acute Ischemic Stroke
ClinicalTrials.gov study NCT01378468. IPD Sharing: Not stated. Countries: 1. Publications: 4.
The Effect of Intranasal Insulin on Hepatic and Intestinal Triglyceride-rich Lipoprotein Production
ClinicalTrials.gov study NCT03141827. IPD Sharing: NO. Countries: 1. Publications: 1.
A Trial Investigating the Effect of Oral Semaglutide Compared With Placebo on Postprandial Glucose and Triglyceride Metabolism, Energy Intake, Appetite Sensations and Gastric Emptying in Subjects With
ClinicalTrials.gov study NCT02773381. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Role of Brown Adipose Tissue in Triglyceride Clearance in People
ClinicalTrials.gov study NCT02786251. IPD Sharing: NO. Countries: 1. Publications: 1.
The Early and Late Contribution of Fasting and Postprandial Triglycerides on Newborn Subcutaneous and Intrahepatic Fat in Pregnancy
ClinicalTrials.gov study NCT04394806. IPD Sharing: NO. Countries: 1. Publications: 1.
Postprandial Triglyceride Impact on Coronary Atherosclerosis in Non-Diabetic Patient in Sohag University Hospital
ClinicalTrials.gov study NCT06501287. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Bioavailability of Fish Oils: Emulsified Versus Capsular Triglyceride
ClinicalTrials.gov study NCT01488747. IPD Sharing: NO. Countries: 1. Publications: 1.
The Effect of Fish Oil Plus Fenofibrate on Triglyceride Levels in People Taking Highly Active Antiretroviral Therapy (HAART)
ClinicalTrials.gov study NCT00076518. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Influence of OCTN2 Variants on Carnitine Status and Plasma Triglycerides
ClinicalTrials.gov study NCT00187733. IPD Sharing: Not stated. Countries: 1. Publications: 1.
VLDL-triglyceride Kinetics in Type 2 Diabetes
ClinicalTrials.gov study NCT01037647. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Effect of Extraneal (Icodextrin)on Triglyceride Levels in PD Patients
ClinicalTrials.gov study NCT00397358. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Very-Low-Density-Lipoprotein-Triglyceride(VLDL-TG) Metabolism During Acute Hyperglycemia
ClinicalTrials.gov study NCT01178957. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Phase 3 STudy of CaPRe In LOwering Very hiGh TriglYcerides (TRILOGY 1)
ClinicalTrials.gov study NCT03398005. IPD Sharing: NO. Countries: 1. Publications: 1.
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