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6,039 results for “adolescence”
Extended data for "TeenCovidLife: A resource to understand the impact of the Covid-19 pandemic on adolescents in Scotland"
<p>Extended data for "TeenCovidLife: A resource to understand the impact of the Covid-19 pandemic on adolescents in Scotland" Wellcome Open Research submission</p>
Mu-opioid receptor-dependent changes in social reward across adolescence in mice
<p>Datasets used in publication "Mu-opioid receptor-dependent changes in social reward across adolescence in mice" (in preparation). The social conditioned place preference data were pre-processed before statistical analysis. Three diffrent datatables with the same dataset reflect the steps of the pre-processing:</p> <p>1. Animals that spent more than 70% of the pretest time in one of the contexts were excluded (datable "30_70%")</p> <p>2. Outliers were identified using Grubbs test, and removed (datatable "no_outlier")</p> <p>3. In cases where the final number of animals conditioned in each context was not equal (due to an unequal number of animals passing the 70% criterion or unequal number of animals in the litter), we pseudorandomly trimmed the larger group using a Python script (file number 10). The exception from completely random selection was introduced to preserve a mean 50% initial context preference during the pretest</p>
Differentiation of functional networks during long-term memory retrieval in children and adolescents
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Valuation of peers' safe choices is associated with substance-naivete in adolescents'
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Lifestyle habits of adolescents before pandemic and one-year later
<p>The database includes variables related to lifestyle habits (i.e. free-time activities, maladaptive behaviors, sleep quality, screen use) and anxiety of a sample of students (N=153, 16 years mean age, 72% female) who were assessed before pandemic (T0) and one year later (T1).</p>
Data paperhood intentions in adolescents
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Basic visual functions of children and adolescents with Autism, Attention Deficit Hyperactivity Disorder, and Dyslexia
<p>Data for the manuscript Basic visual functions of children and adolescents with Autism, Attention Deficit Hyperactivity Disorder, and Dyslexia</p> <div> </div>
Family Type, Mental and Physical Health of in-school Female Adolescents in Ado-Ekiti, Nigeria
<p>This dataset is based on a cross-sectional survey conducted in Ado-Ekiti, Nigeria among in-school female adolescents. The general objective of the study was to examine the influence of family type on the physical and mental health of in-school female adolescents. The data were obtained in 2017 from in-school female adolescents aged 10-18 years old. The respondents were randomly selected from four purposively selected secondary schools. Two schools were selected from the government-owned public schools and two from schools owned by individuals or private organizations. Nigeria operates a six-year secondary education; three years at the junior secondary school (JSS 1-3) and three years at the senior secondary (SS 1-3). The population for this study excluded students in SS3 because they had just concluded their terminal examination at the time of this study. Using the formula proposed by (Krejcie & Morgan, 1970) for deriving a small sample when the population is known, a sample size of 383 was derived from a population of 1656 female students in the four schools. With 10% added to adjust for non-response, a total of 421 students were involved in the study. The number of respondents allocated to each school was proportional to the size of the female students' population in each school. In each school, respondents were assigned to classes proportional to the size, and the particular respondents were identified using a random number. Data were collected with a self-administered structured questionnaire which was piloted before the actual survey. The data is saved in Stata format. </p> <p>A scale for measuring self-reported mental well was designed using questions adapted from Ross, Mirowsky, & Goldsteen (1990) and (Langton & Berger, 2011). The scale reliability coefficient was 0.85. The students were asked to state how often they experience 22 conditions such as feeling sad, discouraged, lonely, hopeless, worthless, wishing you were dead, having trouble concentrating, having difficulty sleeping, crying, and worried among others. </p> <p>Physical health was measured using a scale generated with questions adapted from (Langton & Berger, 2011; Ross et al., 1990). The students were asked to state the frequency of experiencing seven conditions in the month before the survey: feeling sick, tired, dizzy, having chest pain, a headache, muscle or joint pain, and stomach ache. The response options were every day, more than two times, two times, once, and never, graded 1-5.</p> <p>Family type was categorised in four ways: 1) two-parent and single parent. Two parents comprised of couples who were legally married and those who were living together in a consensual union whereas single parents comprised never married, widowed, divorced, and separated mother or father. 2) two-parent (monogamous), two-parent (polygynous), and single parent 3) two-parent, single father, and single mother 4) two-parent, never married, widowed, divorced, and separated</p>
Data supporting the manuscript "Sexually divergent development of depression-related brain networks during healthy human adolescence"
<p>This data supports the manuscript "Sexually divergent development of depression-related brain networks during healthy human adolescence" by Dorfschmidt et al. Part of these <a href="https://doi.org/10.6084/m9.figshare.11551602">data</a> were initially released by Váša et al. (2020) as part of their <a href="https://doi.org/10.1073/pnas.1906144117">manuscript</a>. Please cite them when using these data. </p> <p> </p>
Investigating the "two-hit hypothesis": effects of prenatal maternal immune activation and adolescent cannabis use on neurodevelopment in mice
<p>Prenatal exposure to maternal immune activation (MIA) and chronic adolescent cannabis use have both been identified as environmental risk factors for neuropsychiatric disorders. However, most individuals exposed to a single risk factor do not typically develop major mental illness, which suggests that multiple exposures may be required for illness onset. Here, we examine whether combined exposure to prenatal MIA and adolescent delta-9-tetrahydrocannabinol (THC), the main psychoactive component of cannabis, lead to enduring neuroanatomical and behavioural changes in adult offspring, potentially reflecting changes in humans indicative of mental illness. </p> <p>Mice were prenatally exposed to a viral mimetic, poly I:C (5mg/kg), or vehicle at gestational day (GD)9, and then postnatally exposed to chronic THC (5mg/kg) or vehicle by intraperitoneal injections during adolescent development (postnatal day [PND]28-45). Longitudinal in vivo whole-brain magnetic resonance imaging (MRI) was performed pre-treatment, PND25, post-treatment, PND50, and in adulthood, PND85, followed by a series of behavioural tests aimed at assessing anxiety-like and locomotor, social, and sensorimotor gating behaviour. Post-mortem assessment of cannabinoid (CB)1 and 2 receptor expressing cells was performed in developmentally altered regions identified by MRI (anterior cingulate and somatosensory cortices, striatum, and hippocampus). We hypothesized that there would be differential, but synergistic effects of each exposure.</p> <p>Briefly, we found subtle deviations in neurodevelopmental trajectory and subthreshold anxiety-like behaviours were observed in mice exposed to both risk factors. Sex-dependent effects were observed in patterns of shared brain-behaviour covariation, suggesting that exposure to MIA and THC may affect males and females in different ways. Density of CB1 and CB2 receptor positive cells was significantly decreased in all regions assessed for all mice exposed to either one or both risk factors, relative to controls.</p> <p>These findings suggest that there may be a cumulative effect of risk factor exposure on gross neuroanatomical and behavioural development, and that the endocannabinoid system may be sensitive to both prenatal MIA, adolescent THC, or the combination. For full details, see our publication: .</p> <p>In this dataset, you will find a total of 243 preprocessed structural MRIs (in MINC format) acquired at postnatal day ~25, ~50, and ~85 in mice exposed to poly I:C or vehicle control (0.9% sterile saline) at GD9, and then postnatally treated with vehicle or THC from PND 28-45. These are T1-weighted structural images at 100 micron isotropic resolution acquired on a 7 Tesla Bruker Biospec 70/30; matrix size of 180 x 160 x 90; 14.5 minutes, 20 degrees and TE/TR of 4.5/20 ms (2 averages, ~14 minutes). Anesthesia was induced with 3% isoflurane in oxygen and a (0.075 mg/kg bolus) dexmedetomidine injection. Anesthesia was maintained during the scan between 1.5-0.5% isoflurane, and a constant infusion of dexmedetomidine (0.05mg/kg/h continuous mg/kg during scan). T1-weighted scans were preprocessed by stripping native coordinates, flipping left-right to maintain fidelity, denoising, correcting inhomogeneities in the bias field using the N4 algorithm, and registering in LSQ6 alignment (i.e. 6 degrees of freedom are allowed for imagine alignment: translations and rotations along x, y, and z dimensions). The demographics information for each animal is included in the demographics.csv file. </p> <p>Behavioural tests were performed following the postnatal day 85 scans in all animals with a 2 day rest period. These include: open field test, three chambered social approach, and prepulse inhibition. The data for all of these tests is presented in its own individual .csv spreadsheet.</p> <p>Included in this data set are the structural MRIs in MINC format, the behavioural .csv data, and a readme.txt file providing further detail on the data structure and content, and on how to interpret the data column titles. DICOMS are also available for the structural MRI data, as are the raw (not-preprocessed) MINC files, available upon request to the authors. </p> <p>Finally, the authors would like to acknowledge the funding bodies that supported the completion of this work including the Canadian Institute for Health Research, the Fonds de Recherche du Québec en Santé, and the Healthy Brains for Healthy Lives at McGill University.</p>
Factors associated with child abuse in children and adolescents in a Peruvian public hospital
<p>The study's objective was to determine the factors associated with the type of child and adolescent abuse of the MAMIS program, Hipólito Unanue hospital, Tacna-Peru region, 2019-2021. It had a quantitative, retrospective, cross-sectional, correlational approach in which 174 child abuse cases in children and adolescents were examined. It was found that the predominant personal factors were located in the ages of 12-17 years (57.4%), secondary level (51.15%), female sex (56.9%), and do not consume alcohol and/or drugs (88.5%). The family factors that stood out were the type of single parenteral family (48.28%), the age of both parents was 30-59 years (58.5%), the divorced, marital status (37.3%), secondary level (68.9%), the occupation of the independent parents (64.9%), there is no history of the parents having suffered violence (91.3%), there are no problems of addiction or alcohol consumption and/or drugs (95.40%), and at the same time there are no psychiatric disorders (95.4%). The types of child abuse that prevails is the psychological type (93.68%), followed by the type of neglect or abandonment (38.51%), the physical type (37.93%), and sexual abuse (27.0%). It is concluded that there is a significant relationship, with a confidence level of 95%, between personal factors such as the age of the minor with psychological abuse and sexual abuse<strong>; </strong>the sex of the minor with physical abuse and sexual abuse; the consumption of alcohol and/or drugs with the physical abuse of children and adolescents.</p>
Challenges faced by adolescent girls on Menstrual Hygiene Management: School-based study, Siha, Kilimanjaro, Tanzania
<p><span>Menstrual hygiene management (MHM) has received increasing attention as a public health issue globally. Governments and stakeholders have started to engage communities to address barriers and challenges faced by adolescents in and out of school. </span><span>This study, conducted in Siha District, northern Tanzania, responds to the call for evidence sensitive to local barriers and challenges to inform successful strategies in MHM. </span></p> <p><strong><span>Methods:</span></strong></p> <p><span>Institutional-based cross-sectional study which involved 400 school girls aged 10 to 19 years old who attained menarche were randomly selected in four secondary and advanced level government schools from September 2019 to January 2020. Bivariate and multivariable logistic regression analysis were employed. A P-value less than 0.05 was used to declare statistical significance.</span></p> <p><strong><span>Results:</span></strong></p> <p><span>Among all the girls who participated in the study 30% reported missing school due to menstruation while 56% of the girls reported using toilets as changing places at school. The use of reusable sanitary material was 52% compared with non-reusable materials which was 48%. In urban areas, 34.5% of students reported missing school due to menstruation compared to 25% who reported in rural areas. The findings show that school absenteeism among adolescent girls during menstruation is significantly associated with a headache (Adjusted odds ratio (AOR) = 3.3 (95% CI:1.32 – 8.23)) and abdominal waist pain (AOR = 8.50 (95% CI: 6.27 – 15.56)),</span> <span>lack of changing rooms in school (AOR = 5.85 (95% CI: 4.82 – 7.93)). In addition, the high cost of sanitary pads was mentioned as one of the main reasons for students not using sanitary pads.</span></p> <p><strong><span>Conclusion:</span></strong></p> <p><span>This study calls for promoting MHM-friendly practices in schools to create a supportive and conducive learning environment for adolescent girls. Ongoing school infrastructure improvements such as the construction of classrooms and toilets in schools should include the construction of proper changing places to reduce the number of adolescent girls who miss school due to menstruation. </span></p> <p><span> </span></p>
Self-reported and accelerometry measures of sleep components in adolescents living in Pacific Island countries and territories: Exploring the role of sociocultural background
<p>Data from self-report questionnaires and accelerometer extraction on sleep components (onset sleep time, wake-up time and sleep duration on weekdays and weekend).</p> <p>Participant characteristics: 10 to 16 years old students.</p> <p>Number of participants: 182.</p> <p>Year of the study: 2018 - 2019.</p> <p>Place of the study: New Caledonia.</p>
Hunter-gatherer child and adolescent height and tricep skinfold measures
<p>Despite agreement that humans have evolved to be unusually fat primates, adipose patterning among hunter-gatherers has received little empirical consideration. Here we consider the development of adiposity among four contemporary groups of hunter-gatherers, the Aka, Savanna Pumé, Ju'/Hoansi and Agta using multi-level generalized additive mixed modeling (GAMM) to characterize growth of tricep skinfolds from early childhood through adolescence. In contrast to references, hunter-gatherers show several consistent patterns: 1) children are lean with little fat accumulation; 2) no adiposity rebound at 5 years is evident; 3) girls on average build 90% of their body size, and reach menarche when adiposity is at its maximum velocity; 4) a metabolic tradeoff is evident in young, but not older children, such that both boys and girls prioritize skeletal growth during middle childhood, a tradeoff that diminishes during adolescence when height velocity increases in pace with fat accumulation. Consistent results across hunter-gatherers living in diverse environments suggests that these patterns reflect a general forager pattern of development. The findings provide a valuable baseline for adipose development not apparent from reference populations. We emphasize both generalized trends among hunter-gatherers, and that inter-populational differences point to the plasticity with which humans organize growth and development.</p>
Supplementary file 48 in Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents - assessment of possible adverse events in non-randomised studies
<p>Supplementary file 48: Proportion of patients on methylphenidate with agitation</p>
Supplementary file 51 in Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents - assessment of possible adverse events in non-randomised studies
<p>Supplementary file 51: Proportion of patients on methylphenidate with sleep disorder</p>
Supplementary file 47 in Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents - assessment of possible adverse events in non-randomised studies
<p>Supplementary file 47: Proportion of patients on methylphenidate with isolation</p>
Supplementary file ROBINS-I Risk of Bias table in Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents - assessment of possible adverse events in non-randomised studies.
<p>ROBINS-I Risk og Bias Table</p>
Supplementary file 19 in Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents - assessment of possible adverse events in non-randomised studies
<p>Supplementary file 19 Proportion of patients on methylphenidate with asthenia </p>
Supplementary file 13 in Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents - assessment of possible adverse events in non-randomised studies
<p>Supplementary file 13: Proportion of patients on methylphenidate with tachycardia </p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.