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ShareScore release 0.9.0
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82 results for “calcium channel”
Calcium Channel Splice Variant Expression in Cardiovascular Disease and Aging
ClinicalTrials.gov study NCT00251615. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Calcium Channel Blockers Compared to Magnesium Sulfate in Fetal Cerebral Blood Flow
ClinicalTrials.gov study NCT02591004. IPD Sharing: Not stated. Countries: 1. Publications: 4.
An Observational Study to Describe the Effectiveness of Angiotensin Converting Enzyme Inhibitor and Calcium Channel Blocker Combination in the Management of Hypertensive Patients With Elevated Heart R
ClinicalTrials.gov study NCT02298556. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effectiveness of Calcium Channel Blockade for OP and Carbamate Pesticide Poisoning
ClinicalTrials.gov study NCT03925025. IPD Sharing: YES. Countries: 1. Publications: 1.
Effectiveness of Calcium Channel Blockers and Adenosine in the Emergency Management of SVT
ClinicalTrials.gov study NCT00413712. IPD Sharing: Not stated. Countries: 1. Publications: 23.
The Effects of Renin Angiotensin System Blockage (RAS), Calcium Channel Blocker and Combined Drugs on TWEAK, PTX3 and FMD Levels in Diabetic Proteinuric Patients With Hypertension
ClinicalTrials.gov study NCT00921570. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effect of Calcium Channel Blocker on the Serum Fibrobalst Growth Factor-23 (FGF-23) Levels in Type-2 Diabetic Patients With Proteinuria Purpose
ClinicalTrials.gov study NCT01738945. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events
Open the record for dataset details and reuse information.
Data from: Mutations of the calcium channel gene cacophony suppress seizures in Drosophila
Bang sensitive (BS) Drosophila mutants display characteristic seizure-like phenotypes resembling, in some aspects, those of human seizure disorders such as epilepsy. The BS mutant parabss1, caused by a gain-of-function mutation of the voltage-gated Na+ channel gene, is extremely seizure-sensitive with phenotypes that have proven difficult to ameliorate by anti-epileptic drug feeding or by seizure-suppressor mutation. It has been presented as a model for intractable human epilepsy. Here we show that cacophony (cacTS2), a mutation of the Drosophila presynaptic Ca++ channel α1 subunit gene, is a particularly potent seizure-suppressor mutation, reverting seizure-like phenotypes for parabss1 and other BS mutants. Seizure-like phenotypes for parabss1 may be suppressed by as much as 90% in double mutant combinations with cacTS2. Unexpectedly, we find that parabss1 also reciprocally suppresses cacTS2 seizure-like phenotypes. The cacTS2 mutant displays these seizure-like behaviors and spontaneous high-frequency action potential firing transiently after exposure to high temperature. We find that this seizure-like behavior in cacTS2 is ameliorated by 85% in double mutant combinations with parabss1.
Biophysical characterization of calcium-binding and modulatory-domain dynamics in a pentameric ligand-gated ion channel
<p><strong>Molecular dynamics simulations</strong></p> <p>Trajectories and related files.</p>
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Dihydropyridine Calcium Channel Blockers Versus Hydrochlorothiazide
ClinicalTrials.gov study NCT05125224. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Calcium Channel Blockers (CCBs) or Diuretics as an Add-on to Olmesartan Medoxomil in Hypertension
ClinicalTrials.gov study NCT00858702. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Data from: Mutations of the calcium channel gene cacophony suppress seizures in Drosophila
Open the record for dataset details and reuse information.
Co-expression of calcium channels and delayed rectifier potassium channels protects the heart from proarrhythmic events [Figure 8 mRNA data]
GEO Series GSE146665. Homo sapiens. 12 samples. Type: Other.
Co-expression of calcium channels and delayed rectifier potassium channels protects the heart from proarrhythmic events [Figure 2 mRNA data]
GEO Series GSE146664. Homo sapiens. 16 samples. Type: Other.
A cataract-causing mutation in the TRPM3 cation channel disrupts calcium dynamics in the lens
GEO Series GSE250518. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Differential Expression of Calcium Channels and Signaling Pathways in Hematologic Cancers
GEO Series GSE189927. Homo sapiens. 44 samples. Type: Expression profiling by high throughput sequencing.
RRAD-reduction reveals efficacy of targeting L-type calcium channel regulation for treatment of heart failure
GEO Series GSE304830. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Partial reprogramming of melanoma cells confers drug resistance and increased vulnerability to calcium channel antagonists
GEO Series GSE122763. Mus musculus. 6 samples. Type: Expression profiling by array.
Identifying the Transcriptome Signature of Calcium Channel Blocker in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
GEO Series GSE129793. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.