Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
40
datasets available to search
ShareScore release 0.9.0
Dataset results
40 results for “calcium imaging”
Whole brain Calcium Imaging dataset (CsCl, 1mM NH4Cl, 100mM NH4Cl, SDS)
<p>Data related to the manuscript titled: Polymodal sensory perception drives robust attachment and metamorphosis of a pre-vertebrate zooplanktonic larva. </p>
Data from the paper "A turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calcium"
<p>Data that belongs to the paper "A turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calcium"</p> <p> </p>
APL synapses distribution on PN and KC meshes, primary data, calcium imaging macros and python scripts from Prisco et al.
<p class="MsoBodyText">To identify and memorize discrete but similar environmental inputs, the brain needs to distinguish between subtle differences of activity patterns in defined neuronal populations. The Kenyon cells of the <i>Drosophila </i>adult mushroom body (MB) respond sparsely to complex olfactory input, a property that is thought to support stimuli discrimination in the MB. To understand how this property emerges, we investigated the role of the inhibitory anterior paired lateral neuron (APL) in the input circuit of the MB, the calyx. Within the calyx, presynaptic boutons of projection neurons (PNs) form large synaptic microglomeruli (MGs) with dendrites of postsynaptic Kenyon cells (KCs). Combining EM data analysis and <i>in vivo</i> calcium imaging, we show that APL, via inhibitory and reciprocal synapses targeting both PN boutons and KC dendrites, normalizes odour-evoked representations in MGs of the calyx. APL response scales with the PN input strength and is regionalized around PN input distribution. Our data indicate that the formation of a sparse code by the Kenyon cells requires APL-driven normalization of their MG postsynaptic responses. This work provides experimental insights on how inhibition shapes sensory information representation in a higher brain centre, thereby supporting stimuli discrimination and allowing for efficient associative memory formation.</p>
DeepCAD-RT dataset: synthetic calcium imaging data
<p>DeepCAD-RT dataset: synthetic calcium imaging data</p>
Code and data associated with the paper 'Large-scale calcium imaging reveals a systematic V4 map for encoding natural scenes'
<p>Code and data associated with the paper 'Large-scale calcium imaging reveals a systematic V4 map for encoding natural scenes'.</p> <p>See Readme.pdf for data and code details.</p>
Protocol for Calcium Imaging and Analysis of Hippocampal CA1 Activity Evoked by Non-Spatial Stimuli
Open the record for dataset details and reuse information.
Calcium imaging in visual cortex during fidget behaviors in mice
<p><span>Multiple recent studies have shown that motor activity greatly impacts the activity of primary sensory areas like V1. Yet, the role of this motor related activity in sensory processing is still unclear. </span></p> <p><span>Here we dissect how these behavior signals are broadcast to different layers and areas of the visual cortex. To do so, we leveraged a standardized and spontaneous behavioral fidget event in passively viewing mice. Importantly, this behavior event had no relevance to any ongoing task allowing us to compare its neuronal correlates with visually relevant behaviors (e.g running). </span></p> <p><span>A large two-photon Ca</span><span><span>2+</span></span><span> imaging database of neuronal responses uncovered four neural response types during fidgets that were consistent in their proportion and response patterns across all visual areas and layers of the visual cortex. Indeed, the layer and area identity could not be decoded above chance level based only on neuronal recordings. In contrast to running behavior, fidget evoked neural responses that were independent to visual processing. </span></p> <p><span>The broad availability of visually orthogonal standardized behavior signals could be a key component in how the cortex selects, learns and binds local sensory information with motor outputs. Contrary to behaviorally relevant motor outputs, irrelevant motor signals could project to separate local neural subspaces.</span></p> <p><span></span></p>
SRDTrans dataset: simulated calcium imaging data sampled at 30 Hz under different SNRs
<p>SRDTrans dataset: simulated calcium imaging data sampled at 30 Hz under different SNRs.</p>
SRDTrans dataset: simulated calcium imaging data at different imaging speeds
<p>SRDTrans dataset: simulated calcium imaging data at different imaging speeds</p>
SRDTrans dataset: simulated calcium imaging data sampled at 30 Hz under different SNRs
<p>SRDTrans dataset: simulated calcium imaging data sampled at 30 Hz under different SNRs.</p>
APL synapses distribution on PN and KC meshes, primary data, calcium imaging macros and python scripts from Prisco et al.
Open the record for dataset details and reuse information.
Calcium imaging in visual cortex during fidget behaviors in mice
Open the record for dataset details and reuse information.
Teena Calcium Imaging Example Video
<p>Single examples of a calcium imaging movie with artifacts, and after artifact removal.</p> <p> </p>
Calcium imaging
SciDraw upload
Data from: Calcium imaging with genetically encoded sensor Case12: facile analysis of α7/α9 nAChR mutants
Open the record for dataset details and reuse information.
Data from: Comparing analysis methods in functional calcium imaging of the insect brain
Open the record for dataset details and reuse information.
Wide-field cortical calcium imaging data from behaving mice
<p>This data release contains simultaneous recordings of fluorescent<br>signals of the mouse cortex by wide-field calcium imaging and behavioral<br>activity from 5 animals.<br><br>These data were used in</p> <p>Ajioka T, Nakai N, Yamashita O, Takumi T (2024) End-to-end deep learning approach to mouse behavior classification from cortex-wide calcium imaging. PLoS Comput Biol 20(3): e1011074. https://doi.org/10.1371/journal.pcbi.1011074</p> <p><a href="https://doi.org/10.1371/journal.pcbi.1011074">https://doi.org/10.1371/journal.pcbi.1011074</a></p> <p> </p> <p>The code to make the figures in the paper is available at<br><br><a href="https://github.com/atakehiro/Neural_Decoding_from_Calcium_Imaging_Data" target="_blank" rel="noopener noreferrer">https://github.com/atakehiro/Neural_Decoding_from_Calcium_Imaging_Data</a><br><br>If you use these data in a paper, please cite the original research<br>paper, as well as this dataset using the Zenodo doi.</p>
Does OCT Imaging Allow us to See Blood Vessel Development in and Around Deposits of Fat and Calcium Inside Blood Vessels
ClinicalTrials.gov study NCT03182348. IPD Sharing: NO. Countries: 1. Publications: 0.
A Systematically Optimized Miniaturized Mesoscope (SOMM) for large-scale calcium imaging in freely moving mice (Deprecated)
Open the record for dataset details and reuse information.
Which are the most frequently involved peripheral joints in calcium pyrophosphate crystal deposition at imaging? A Systematic Literature Review and meta-analysis by the OMERACT Ultrasound – CPPD subgroup
<p><strong>Objectives</strong>: To identify the prevalence of calcium pyrophosphate crystal deposition (CPPD) using ultrasound and conventional radiology at peripheral joints in patients with suspected or definite CPPD.</p> <p><strong>Methods: </strong>A systematic literature search was performed in PubMed and Embase using pre-defined search strategies from inception to April 2021 to identify studies that evaluated conventional radiology and ultrasound in detecting CPPD at peripheral joints, including definite or suspected CPPD [Research question 1 (RQ1) and Research Question 2 (RQ2), respectively]. For the meta-analysis, the first, second, and third sub-analysis included studies with the knee, and knee or wrist as the index joint for CPPD (without restrictions on the reference standard) and synovial fluid analysis or histology as a reference standard (without restrictions on the index joint), respectively.</p> <p><strong>Results: </strong>One-thousand eight hundred and twenty-seven manuscripts were identified, of which 94 articles were finally included. Twenty-two and seventy-two papers were included in RQ1 and RQ2, respectively. The knee had the highest prevalence for RQ1 and RQ2 by both conventional radiology and ultrasound, followed by the wrist with the highest prevalence for RQ1. The hand had the lowest CPPD prevalence. The third sub-analysis showed a higher CPPD prevalence on ultrasound than conventional radiology at the knee (only data available).</p> <p><strong>Conclusion: </strong>Among all peripheral joints, the knees and wrists could be regarded as the target joints for CPPD detection by imaging. Furthermore, ultrasound seems to detect a higher number of calcium pyrophosphate deposits than conventional radiology, even when using a more restrictive reference standard.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.