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Fig. 4 in Multivariate analysis of chemical and genetic diversity of wild Humulus lupulus L. (hop) collected in situ in northern France
Fig. 4. Results of characterization of soil samples collected close to the root environment of the 63 hops studied. These 63 hops samples are represented by ten commercial varieties: Nugget comes from « comm_1 »; Strisselspalt comes from « comm_2 » and other commercial cultivars come from the same field « comm_3–10 »; three heirloom varieties coming from the same field identified as « old »; and fifty wild hops identified according to Table 1. The characterization of soil samples was based on pH and conductivity measurements, on organic matter content determined by loss of ignition as well as on dosage of the sodium, potassium, calcium and magnesium elements. A. Dendrogram including hierarchical cluster analysis (N = 8) among soil samples determined by soil characterization. B. Heatmap associated to the dendrogram. The 8 clusters of the hierarchical clustering were reported on the heatmap. C. Pictures of soil samples from locations B (Tourbi`ere de Vred, Vred) (1), D (Cap Blanc nez, Wissant) (2) and K (Dunes d'Ecault) (3).
Fig. 1. Main hop prenylated phenolic compounds A in Multivariate analysis of chemical and genetic diversity of wild Humulus lupulus L. (hop) collected in situ in northern France
Fig. 1. Main hop prenylated phenolic compounds A. Chemical structure of major chalcones and acylphloroglucinols produced by hops and their molecular weight. B. Chromatogram of a crude hydro-ethanolic extract of hops (cultivar Nugget) at 330 nm. XN: xanthohumol, α1: co-humulone; α2: humulone; α3: ad-humulone; β1: colupulone; β2: lupulone; β3: ad-lupulone.
Fig. 3 in Multivariate analysis of chemical and genetic diversity of wild Humulus lupulus L. (hop) collected in situ in northern France
Fig. 3. Geographical repartition of the fifty accessions of wild hop (Humulus lupulus L.) collected on the 11 locations A to K in the North of France.
Fig. 8. Untargeted metabolomic analysis A in Multivariate analysis of chemical and genetic diversity of wild Humulus lupulus L. (hop) collected in situ in northern France
Fig. 8. Untargeted metabolomic analysis A. Principle component analysis of the 63 chemotypes of hop studied. Each symbol represents a single plant from the different accessions. Commercial varieties (10 accessions), heirloom varieties (3 accessions), wild hops collected on different locations (50 accessions, Fig. 3). B. Principle component analysis of the chemical markers.
Fig. 7 in Multivariate analysis of chemical and genetic diversity of wild Humulus lupulus L. (hop) collected in situ in northern France
Fig. 7. Results of the statistical treatment of data for the quantitation of xanthohumol, co-, n-, ad-humulone and co-, n-, ad-lupulone. This quantitation has been performed on the 63 crude hydro-ethanolic extracts of hop cone powder from Northern France, including 10 commercial varieties, 3 heirloom varieties and 50 wild hops (Fig. 1, Table 2). A. PCA biplot of quantitation data with score plot and loading plot of variables. Individuals were colored by collection site for a given observation. Variable contribution to component was represented by arrows length. B. Dendrogram of the hierarchical cluster analysis among the 63 hops based on the quantitation similarity (Ward's method, distance scale) (N = 3).
Fig. 3 in Authenticating wild Piper species (peppers) originating from islands in the Indian Ocean on the basis of morphological, genetic and chemical characteristics
Fig. 3. Phylogenetic dendrogram obtained from the combined sequences (Its + psbJ-petA) using the Neighbour Joining (NJ) method.
Fig. 6 in Assessing the genetic and chemical diversity of Taraxacum species in the Korean Peninsula
Fig. 6. The chemical dendrogram obtained by HCA (Euclidean distance and Ward's linkage method) on the LC–MS feature table. TCA: T. campylodes; TCO: T. coreanum; TE: T. erythrospermum; TU: T. ussuriense; TP: T. platycarpum.
Fig. 5 in Assessing the genetic and chemical diversity of Taraxacum species in the Korean Peninsula
Fig. 5. Bar plots showing the ion intensities of selected defensive metabolites (3, 5, 7, 9, 14, 16, 17, 18, and 19) in analyzed Taraxacum samples. TCA: T. campylodes; TCO: T. coreanum; TE: T. erythrospermum; TU: T. ussuriense; TP: T. platycarpum.
Fig. 3 in Assessing the genetic and chemical diversity of Taraxacum species in the Korean Peninsula
Fig. 3. LC–MS base peak ion (BPI) chromatograms of 13 Taraxacum extracts. The selected major chromatographic peaks are annotated with peak numbers. T. campylodes, T. coreanum, and T. platycarpum were triplicated, while T. erythrospermum and T. ussuriense were duplicated. Gaps between the chromatograms were added to help visualize the differences, so the y-axis values do not equal the absolute intensities.
Fig. 1 in Assessing the genetic and chemical diversity of Taraxacum species in the Korean Peninsula
Fig. 1. Maps of the complete chloroplast genomes and 45S rDNA units of six Taraxacum species and the locations of polymorphic regions. The number of variable regions for each species is in Table 2 for the chloroplast genomes and Table 3 for the 45S rDNA. (A) The chloroplast genome map of the six Taraxacum species. Polymorphic regions among the species are indicated inside the circle in black and red bars for SNP and InDel, respectively. The innermost graph is Pi value representing nucleotide diversity. (B) The 45S rDNA coding region of the six Taraxacum species. SNPs and IndeLs among the six Taraxacum species are represented in blue and red, respectively. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 2 in Assessing the genetic and chemical diversity of Taraxacum species in the Korean Peninsula
Fig. 2. The phylogenomic relationship of Taraxacum species based on chloroplast (CP) and 45S rDNA. The phylogenetic position of each species was analyzed using 74 protein coding sequences from the CP genomes and 45S rDNA transcription unit sequences, along with previously reported CP sequences and 45S rDNA (Genbank accession number: MT003979) of Artemisia fukudo (Asteraceae) (Whitehead and Bowers, 2013).
Fig. 5 in Genetic and chemical diversity of the toxic herb Jacobaea vulgaris Gaertn. (syn. Senecio jacobaea L.) in Northern Germany
Fig. 5. Principal co-ordinate analysis (PCoA) ordination of the genetic similarity of 75 individuals of J. vulgaris from Northern Germany. Coordinate 1 explains 29.47% of the shown variability and coordinate 2 explains 10.00% of the shown variability. Colours indicate membership to the different populations.
Fig. 3 in Genetic and chemical diversity of the toxic herb Jacobaea vulgaris Gaertn. (syn. Senecio jacobaea L.) in Northern Germany
Fig. 3. PA content and composition of J. vulgaris. A) Averaged PA content in mg/kg dry weight of the individuals per population (± SEM). At first total PA content of every individual was calculated and afterwards the mean content of all individuals per population. Significant differences to the total averaged PA content (dotted line) are indicated by *. B) PA diversity of the populations shown by mean numbers of different PAs detected in populations (± SEM). Significant differences to the total averaged number of PA (dotted line) are indicated by *. C) Categorisation of J. vulgaris chemotypes: Difference in relative abundance of erucifoline and jacobine per population. Bars below 0 indicate jacobine type and bars over 0 indicate erucifoline type populations. *p <0.05, **p <0.01, ***p <0.001.
Chemical and Genetic Effects of the Experimental Anti-Cancer Drugs in Cheek Cells in Cancer Patients
ClinicalTrials.gov study NCT00055380. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Data from: Effect of plant chemical variation and mutualistic ants on the local population genetic structure of an aphid herbivore
Open the record for dataset details and reuse information.
Transcriptome dataset to: Chemical genetics in Silene latifolia elucidate regulatory pathways involved in gynoecium development
Open the record for dataset details and reuse information.
Data from: Variation in the level of aggression, chemical and genetic distance among three supercolonies of the Argentine ant in Europe
In their invasive ranges, Argentine ant populations often form one geographically vast supercolony, genetically and chemically uniform within which there is no intraspecific aggression. Here we present regional patterns of intraspecific aggression, cuticular hydrocarbons and population genetics of 18 nesting-sites across Corsica and the French mainland. Aggression tests confirm the presence of a third European supercolony, the Corsican supercolony, which exhibits moderate to high levels of aggression, depending on nesting-sites, with the Main supercolony, and invariably high levels of aggression with the Catalonian supercolony. The chemical analyses corroborated the behavioral data, with workers of the Corsican supercolony showing moderate differences in cuticular hydrocarbons compared to workers of the European Main supercolony and strong differences compared to workers of the Catalonian supercolony. Interestingly, there were also clear genetic differences between workers of the Catalonian supercolony and the two other supercolonies at both nuclear and mitochondrial markers, but only very weak genetic differentiation between nesting-sites of the Corsican and Main supercolonies (FST = 0.06). A detailed comparison of the genetic composition of supercolonies also revealed that, if one of the last two supercolonies derived from the other, it is the Main supercolony that derived from the Corsican supercolony rather than the reverse. Overall, these findings highlight the importance of conducting more qualitative and quantitative analyses of the level of aggression between supercolonies, which has to be correlated with genetic and chemical data.
Data from: Novel adverse outcome pathways revealed by chemical genetics in a developing marine fish
Crude oil spills are a worldwide ocean conservation threat. Fish are particularly vulnerable to the oiling of spawning habitats, and crude oil causes severe abnormalities in embryos and larvae. However, the underlying mechanisms for these developmental defects are not well understood. Here, we explore the transcriptional basis for four discrete crude oil injury phenotypes in the early life stages of the commercially important Atlantic haddock (Melanogrammus aeglefinus). These include defects in (1) cardiac form and function, (2) craniofacial development, (3) ionoregulation and fluid balance, and (4) cholesterol synthesis and homeostasis. Our findings suggest a key role for intracellular calcium cycling and excitation-transcription coupling in the dysregulation of heart and jaw morphogenesis. Moreover, the disruption of ionoregulatory pathways sheds new light on buoyancy control in marine fish embryos. Overall, our chemical-genetic approach identifies initiating events for distinct adverse outcome pathways and novel roles for individual genes in fundamental developmental processes.
Fig. 4 in Authenticating wild Piper species (peppers) originating from islands in the Indian Ocean on the basis of morphological, genetic and chemical characteristics
Fig. 4. Content (g/100 g DM) in piperine and essential oil of the three wild peppers studied.
Fig. 2 in Authenticating wild Piper species (peppers) originating from islands in the Indian Ocean on the basis of morphological, genetic and chemical characteristics
Fig. 2. Fruiting twigs, leaves and berries of the three wild peppers studied.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.