Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
73
datasets available to search
ShareScore release 0.9.0
Dataset results
73 results for “chitin”
A type 2 immune circuit in the stomach controls mammalian adaptation to dietary chitin
<p>Dietary fiber improves metabolic health, but host-encoded mechanisms for digesting fibrous polysaccharides are unclear. Here, we describe a mammalian adaptation to dietary chitin that is coordinated by gastric innate immune activation and acidic mammalian chitinase (AMCase). Chitin consumption causes gastric distension and cytokine production by stomach tuft cells and group 2 innate lymphoid cells (ILC2s), driving expansion of AMCase-expressing zymogenic chief cells that facilitate chitin digestion. Although chitin influences microbial composition, ILC2-mediated tissue adaptation and gastrointestinal responses are preserved in germ-free mice. In the absence of AMCase, sustained chitin intake leads to heightened basal type 2 immunity, reduced adiposity, and resistance to obesity. These data define an endogenous metabolic circuit that enables nutrient extraction from an insoluble dietary constituent by enhancing digestive function.</p>
A type 2 immune circuit in the stomach controls mammalian adaptation to dietary chitin
Open the record for dataset details and reuse information.
Data from: Requirement of group I lytic polysaccharide monooxygenase for turnover of chitinous cuticle during molting in two forest pest beetles, <em>Monochamus alternatus</em> and <em>Psacothea hilaris</em>
Open the record for dataset details and reuse information.
Functional miscibility and thermomechanical properties enhancement of substituted phthalic acetylated modified chitin filler in biopolymer composite
Open the record for dataset details and reuse information.
Liquid chromatography measurement obtained from the chitin extracts of insect exuviae
<p>Chitin, a biopolymer present in fungi and arthropods, is a compound of interest for various applications, such as in the agricultural and medical fields. With the recently growing interest in the development of insect farming, the availability of chitin-containing residual streams, particularly the molting skins (exuviae), is expected to increase in the near future. For application purposes, accurate quantification of chitin in these insect sources is essential. Previous studies on chitin extraction and quantification often overlooked the purity of the extracted chitin, making the outcomes inconsistent and prone to overestimation. The present study aims to determine chitin content in the exuviae of three insect species mass-reared worldwide: black soldier fly (BSF), mealworm, and house cricket. Chitin was chemically extracted using acid and alkali treatments to remove minerals and proteins. The purity of extracted chitin was evaluated by hydrolyzing the chitin into glucosamine, followed by quantitative determination of the latter using two liquid chromatography methods: electrochemical detection (ECD) and tandem mass spectrometry (MS/MS). Both methods proved accurate and precise, without the need for labor-intensive derivatization steps. Pearson's correlation and Bland-Altman plots showed that the glucosamine determination results obtained by the two methods were comparable, and there is no consistent bias of one approach vs. the other. The chitin content in extracted residues ranged between 7.9 and 18.5%, with the highest amount<br> found in BSF puparium. In summary, the study demonstrated that (1) the residual streams of the insect farming industry have a great potential for utilization as an alternative chitin source, and (2) both LC-ECD and LC-MS/MS are reliable for the quantitative determination of glucosamine in insect chitin.</p>
Effects of Chitin-Glucan on Oxidized Low-Density Lipoprotein (LDL)
ClinicalTrials.gov study NCT01232309. IPD Sharing: Not stated. Countries: 2. Publications: 6.
Measuring Dietary Iron Absorption From Edible Insects and Assessing the Effect of Chitin Content on Iron Bioavailability (Study 1)
ClinicalTrials.gov study NCT04510831. IPD Sharing: NO. Countries: 1. Publications: 1.
Characterization of Chitin-glucan Fiber Fermentation in Human After a Single Administration
ClinicalTrials.gov study NCT03494491. IPD Sharing: YES. Countries: 1. Publications: 1.
Liquid chromatography measurement obtained from the chitin extracts of insect exuviae
Open the record for dataset details and reuse information.
Fig. 3 in Molecular and physiological characterization of the chitin synthase B gene isolated from CUlex pipieNS palleNS (Diptera: Culicidae)
Fig. 3 Expression profiles of CpCHSB during different developmental stages. Stages include egg (EG), fourth-instar larvae (L4), pupae (PU), post-eclosion (PE), and post-blood meal (PBM). Relative expression levels were calculated based on the lowest expression value, which was ascribed an arbitrary value of 1. Results are shown as the mean ± SE
Data from: Paleozoic diversification of terrestrial chitin-degrading bacterial lineages
Open the record for dataset details and reuse information.
Deletion of the Aspergillus niger pro-protein processing protease gene kexB results in a pH-dependent morphological transition during submerged cultivations and increases cell wall chitin content
GEO Series GSE151618. Aspergillus niger. 4 samples. Type: Expression profiling by high throughput sequencing.
Effect of overexpression of OsTGAP1 in chitin oligosaccharide elicitor-treated rice cells
GEO Series GSE53417. Oryza sativa. 12 samples. Type: Expression profiling by array.
Chitin and Biochar in strawberry cultivation
GEO Series GSE144526. Fragaria x ananassa. 18 samples. Type: Expression profiling by high throughput sequencing.
Manganese homeostasis modulates glucan and chitin unmasking in Candida albicans
GEO Series GSE283948. Candida albicans. 8 samples. Type: Expression profiling by high throughput sequencing.
Expression profiling of Cellvibrio japonicus using either glucose or chitin
GEO Series GSE108935. Cellvibrio japonicus. 6 samples. Type: Expression profiling by high throughput sequencing.
Assessment of transcriptional reprogramming of lettuce roots in response to chitin soil amendment
GEO Series GSE224725. Lactuca sativa var. capitata. 10 samples. Type: Expression profiling by high throughput sequencing.
The function of CEBiP in the chitin elicitor signaling in rice cells
GEO Series GSE4645. Oryza sativa. 4 samples. Type: Expression profiling by array.
The function of CERK1 receptor-like kinase in the chitin elicitor signaling in Arabidopsis
GEO Series GSE9346. Arabidopsis thaliana. 4 samples. Type: Expression profiling by array.
Chitin oligosaccharide elicitor-responsive genes in suspension cultured rice cells
GEO Series GSE53414. Oryza sativa. 8 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.