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503
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Dataset results
503 results for “chronic heart failure”
ContriBution of Digital RemOte MoniToring to IMPROVing The Effectiveness of Treatment in Patients With Chronic Heart Failure With Low Ejection Fraction
ClinicalTrials.gov study NCT06304753. IPD Sharing: NO. Countries: 1. Publications: 0.
EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Preserved Ejection Fraction (EMPEROR-Preserved)
ClinicalTrials.gov study NCT03057951. IPD Sharing: Not stated. Countries: 23. Publications: 20.
Safety of Repeat Doses of IV Serelaxin in Subjects With Chronic Heart Failure
ClinicalTrials.gov study NCT01982292. IPD Sharing: Not stated. Countries: 13. Publications: 1.
Registrational Study With Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure With Reduced Ejection Fraction
ClinicalTrials.gov study NCT02929329. IPD Sharing: YES. Countries: 36. Publications: 10.
EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Reduced Ejection Fraction (EMPEROR-Reduced)
ClinicalTrials.gov study NCT03057977. IPD Sharing: Not stated. Countries: 20. Publications: 29.
This Study Will Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality of Patients With Chronic Heart Failure
ClinicalTrials.gov study NCT01035255. IPD Sharing: Not stated. Countries: 47. Publications: 52.
Ultrasound-assessed Internal Jugular Vein Distensibility in Advanced Chronic Heart Failure (US-IJVD in CHF)
ClinicalTrials.gov study NCT03874312. IPD Sharing: NO. Countries: 1. Publications: 5.
Phase IIb Safety and Efficacy Study of Different Oral Doses of BAY94-8862 in Subjects With Worsening Chronic Heart Failure and Left Ventricular Systolic Dysfunction and Either Type 2 Diabetes Mellitus
ClinicalTrials.gov study NCT01807221. IPD Sharing: Not stated. Countries: 25. Publications: 4.
Clinical Study Of Eplerenone In Japanese Patients With Chronic Heart Failure
ClinicalTrials.gov study NCT01115855. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Harefield Recovery Protocol Study for Patients With Refractory Chronic Heart Failure
ClinicalTrials.gov study NCT00585546. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study of LY3540378 in Participants With Worsening Chronic Heart Failure With Preserved Ejection Fraction (HFpEF)
ClinicalTrials.gov study NCT05592275. IPD Sharing: YES. Countries: 12. Publications: 1.
Innovative Care of Older Adults With Chronic Heart Failure: A Comparative Effectiveness Clinical Trial (I-COACH)
ClinicalTrials.gov study NCT04304833. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Post Marketing Surveillance (PMS) of JARDIANCE in Chronic Heart Failure (CHF)
ClinicalTrials.gov study NCT05262764. IPD Sharing: YES. Countries: 1. Publications: 1.
Evaluation of CLP in Heart Failure Patients With Chronic Kidney Disease
ClinicalTrials.gov study NCT01265524. IPD Sharing: Not stated. Countries: 3. Publications: 1.
Exercise Training Following Cardiac Resynchronization Therapy in Patients With Chronic Heart Failure
ClinicalTrials.gov study NCT02413151. IPD Sharing: Not stated. Countries: 1. Publications: 33.
COSMIC-HF - Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure
ClinicalTrials.gov study NCT01786512. IPD Sharing: Not stated. Countries: 13. Publications: 4.
Effects of a Walking Program and Inspiratory Muscle Training in Individuals With Chronic Heart Failure
ClinicalTrials.gov study NCT01560871. IPD Sharing: Not stated. Countries: 1. Publications: 11.
Integrated Diagnostics Driven Diuretic and Chronic Medication Management for Heart Failure
ClinicalTrials.gov study NCT02698241. IPD Sharing: NO. Countries: 1. Publications: 1.
Determining the Feasibility of Spinal Cord Neuromodulation for the Treatment of Chronic Heart Failure
ClinicalTrials.gov study NCT01112579. IPD Sharing: Not stated. Countries: 8. Publications: 1.
Validation of Soluble Suppression of Tumorigenesis-2, Heart-Type Fatty Acid-Binding Protein and Lipoprotein-Associated Phospholipase A2 as Tools in the Assessment of Chronic Heart Failure
<p>Chronic heart failure (CHF) is a major public health and growing problem, which imposes a relevant burden, with high prevalence and mortality rates. Therefore, reliable cardiac biomarkers are needed to identify individuals with CHF. The goal of this study was to validate the diagnostic utility of some cardiac biomarkers as tools in the assessment of CHF. This was a hospital-based case-control study where a total of 180 participants (aged 30-85 years) consisting of 100 participants with CHF and 80 apparently healthy controls were recruited for the study. Serum troponin I, sST2, H-FABP, and LP-PLA2, were measured using ELISA technique. The value of P≤ 0.05 was regarded as statistically significant. Serum levels of sST2, H-FABP, and Lp-PLA2, were significantly higher in CHF participants when compared with control (p<0.05). Lp-PLA2 had a sensitivity of 99%, specificity of 95%, H-FABP had a sensitivity of 95%, specificity of 100%, and sST2 had a sensitivity of 80%, specificity of 92%, which were all higher when compared with that of Troponin I (20% and 95% respectively).In conclusion, Lp-PLA2, H-FABP, and sST2 were higher in CHF individuals, indicating the possible presence of inflammation and myocardial injury. The markers were more sensitive and specific than troponin I, suggesting their potential use as reliable biomarkers for the assessment of chronic heart failure.</p>
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