Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,808
datasets available to search
ShareScore release 0.9.0
Dataset results
1,808 results for “dendritic cell”
Dynamic interactome of the MHC I peptide loading complex in human dendritic cells - Source III
<p>Source data underlying Raji cell data set (SFig.3). Datafile comprises MS raw data + MaxQuant output files.</p>
CT7, MAGE-A3, and WT1 mRNA-electroporated Autologous Langerhans-type Dendritic Cells as Consolidation for Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation
ClinicalTrials.gov study NCT01995708. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Phase II Feasibility Study of Dendritic Cell Vaccination for Newly Diagnosed Glioblastoma Multiforme
ClinicalTrials.gov study NCT00323115. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Pilot Study of a Dendritic Cell Vaccine in HIV-1 Infected Subjects
ClinicalTrials.gov study NCT00833781. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Dendritic Cell Vaccines + Dasatinib for Metastatic Melanoma
ClinicalTrials.gov study NCT01876212. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Dendritic Cell Vaccine Study (DC/PC3) for Prostate Cancer
ClinicalTrials.gov study NCT00345293. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Tagraxofusp in Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm or Acute Myeloid Leukemia
ClinicalTrials.gov study NCT02113982. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Tagraxofusp in Treating Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm After Stem Cell Transplant
ClinicalTrials.gov study NCT04317781. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Paclitaxel, Cyclophosphamide & Doxorubicin, Autologous Dendritic Cells & Surgery in Stage II/III Breast Cancer (Women)
ClinicalTrials.gov study NCT00499083. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Radiation Therapy and Intratumoral Autologous Dendritic Cells in Soft Tissue Sarcomas (STS)
ClinicalTrials.gov study NCT01347034. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Role of Infected Blood Dendritic Cells in Heart Disease Risk
ClinicalTrials.gov study NCT01568944. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Ad/HER2/Neu Dendritic Cell Cancer Vaccine Testing
ClinicalTrials.gov study NCT01730118. IPD Sharing: YES. Countries: 1. Publications: 3.
External Beam Radiation With Intratumoral Injection of Dendritic Cells As Neo-Adjuvant Treatment for Sarcoma
ClinicalTrials.gov study NCT00365872. IPD Sharing: Not stated. Countries: 1. Publications: 2.
A Pilot Study of Vaccination With Epitope-Enhanced TARP Peptide and TARP Peptide-Pulsed Dendritic Cells in the Treatment of Stage D0 Prostate Cancer
ClinicalTrials.gov study NCT00972309. IPD Sharing: YES. Countries: 1. Publications: 4.
Autologous Dendritic Cell Vaccine in HIV1 Infection
ClinicalTrials.gov study NCT00510497. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Ability of a Dendritic Cell Vaccine to Immunize Melanoma or Epithelial Cancer Patients Against Defined Mutated Neoantigens Expressed by the Autologous Cancer
ClinicalTrials.gov study NCT03300843. IPD Sharing: NO. Countries: 1. Publications: 3.
Identification of signaling networks associated with lactate modulation of macrophages and dendritic cells
Open the record for dataset details and reuse information.
Supplementary data for: Ligand-specific tuning of CLEC10A signalling strength and dendritic cell responses through engagement of different GalNAc-containing glycan structures
Open the record for dataset details and reuse information.
Data from: Illuminating T cell-dendritic cell interactions in vivo by FlAsHing antigens
Open the record for dataset details and reuse information.
Dataset related to article "Costimulatory Molecules and Immune Checkpoints Are Differentially Expressed on Different Subsets of Dendritic Cells."
<p>Dendritic cells (DCs) play a crucial role in initiating and shaping immune responses. The effects of DCs on adaptive immune responses depend partly on functional specialization of distinct DC subsets, and partly on the activation state of DCs, which is largely dictated by environmental signals. Fully activated immunostimulatory DCs express high levels of costimulatory molecules, produce pro-inflammatory cytokines, and stimulate T cell proliferation, whereas tolerogenic DCs express low levels of costimulatory molecules, produce immunomodulatory cytokines and impair T cell proliferation. Relevant to the increasing use of immune checkpoint blockade in cancer treatment, signals generated from inhibitory checkpoint molecules on DC surface may also contribute to the inhibitory properties of tolerogenic DCs. Yet, our knowledge on the expression of inhibitory molecules on human DC subsets is fragmentary. Therefore, in this study, we investigated the expression of three immune checkpoints on peripheral blood DC subsets, in basal conditions and upon exposure to pro-inflammatory and anti-inflammatory stimuli, by using a flow cytometric panel that allows a direct comparison of the activatory/inhibitory phenotype of DC-lineage and inflammatory DC subsets. We demonstrated that functionally distinct DC subsets are characterized by differential expression of activatory and inhibitory molecules, and that cDC1s in particular are endowed with a unique immune checkpoint repertoire characterized by high TIM-3 expression, scarce PD-L1 expression and lack of ILT2. Notably, this unique cDC1 repertoire was subverted in a group of patients with myelodysplastic syndromes included in the study. Applied to the characterization of DCs in the tumor microenvironment, this panel has the potential to provide valuable information to be used for investigating the role of DC subsets in cancer, guiding DC-targeting treatments, and possibly identifying predictive biomarkers for clinical response to cancer immunotherapy.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.