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335 results for “disease resistance”
Data from: Symbiotic immuno-suppression: is disease susceptibility the price of bleaching resistance?
Accelerating anthropogenic climate change threatens to destroy coral reefs worldwide through the processes of bleaching and disease. These major contributors to coral mortality are both closely linked with thermal stress intensified by anthropogenic climate change. Disease outbreaks typically follow bleaching events, but a direct positive linkage between bleaching and disease has been debated. By tracking 152 individual coral ramets through the 2014 mass bleaching in a South Florida coral restoration nursery, we revealed a highly significant negative correlation between bleaching and disease in the Caribbean staghorn coral, Acropora cervicornis. To explain these results, we propose a mechanism for transient immunological protection through coral bleaching: Removal of Symbiodinium during bleaching may also temporarily eliminate suppressive symbiont modulation of host immunological function. We contextualize this hypothesis within an ecological perspective in order to generate testable predictions for future investigation.
Quantitative disease resistance in wild Silene vulgaris to its endemic pathogen Microbotryum silenes-inflatae collection sites
<p>Details presented on the collections sites of <em>Silene vulgaris</em> seeds from natural populations, for use in the study, Quantitative Disease Resistance in wild <em>Silene vulgaris</em> to its Endemic Pathogen <em>Microbotryum silenes-inflatae</em>. In this study the seeds were collected a mixed half and full sibling families (seeds from the same maternal plants) and used to produce plants that were then cloned by vegetative cuttings. The infection rates of these clones, as well as of their F1 offspring, by the fungus Microbotryum silenes-inflatae are also presented.</p>
Assessment of animal diseases caused by bacteria resistant to antimicrobials: Cattle- Appendix B: Excel file with all data extracted
<p>Information on all the full-text studies that were assessed, including the reason for exclusion for those that were excluded at the full-text screening and the data extracted from the included studies, can be consulted here. </p> <p>The extensive literature review was carried out by the University of Copenhagen under the contract OC/EFSA/ALPHA/2020/02 – LOT 1 (https://ted.europa.eu/udl?uri=TED:NOTICE:457654-2020:TEXT:EN:HTML)</p>
Assessment of animal diseases caused by bacteria resistant to antimicrobials: Fishes - Appendix B: Excel file with all data extracted
<p>Information on all the full-text studies that were assessed, including the reason for exclusion for those that were excluded at the full-text screening and the data extracted from the included studies, can be consulted here. </p> <p>The extensive literature review was carried out by the University of Copenhagen under the contract OC/EFSA/ALPHA/2020/02 – LOT 1 (https://ted.europa.eu/udl?uri=TED:NOTICE:457654-2020:TEXT:EN:HTML)</p>
Assessment of animal diseases caused by bacteria resistant to antimicrobials: Rabbits - Appendix B: Excel file with all data extracted
<p>Information on all the full-text studies that were assessed, including the reason for exclusion for those that were excluded at the full-text screening and the data extracted from the included studies, can be consulted here. </p> <p>The extensive literature review was carried out by the University of Copenhagen under the contract OC/EFSA/ALPHA/2020/02 – LOT 1 (https://ted.europa.eu/udl?uri=TED:NOTICE:457654-2020:TEXT:EN:HTML)</p>
Long-read-based draft genome sequence of Indian black gram IPU-94-1 'Uttara': Insights into disease resistance and seed storage protein genes
<p>Black gram [Vigna mungo (L.) Hepper var. <em>mung<a>o</a></em>] [LAV1] is a warm-season legume highly prized for its protein content along with significant folate and iron proportions. To expedite the genetic enhancement of black gram, a high-quality draft genome from the center of origin of the crop is indispensable. Here, we established a draft genome sequence of an Indian black gram cultivar, 'Uttara' (IPU 94-1), known for its high resistance to mungbean yellow mosaic virus. Pacific Biosciences of California, Inc. (PacBio) single-molecule real-time (SMRT) and Illumina sequencing assembled a draft reference-guided assembly with a cumulative size of ~454.4 Mb, of which, 444.4 Mb was anchored on 11 pseudomolecules corresponding to 11 chromosomes. Uttara assembly denotes features of a high-quality draft genome illustrated through high N50 value (42.88 Mb), gene completeness (benchmarking universal single-copy ortholog [BUSCO] score 94.17%), and low levels of ambiguous nucleotides (N) percent (0.0005%). Gene discovery using transcript evidence predicted 28,881 protein-coding genes, from which, ~95% were functionally annotated. A global survey of genes associated with disease resistance revealed 119 nucleotide binding site–leucine rich repeat (NBS-LRR) proteins, while 23 genes encoding seed storage proteins (SSPs) were discovered in black gram. A large set of microsatellite loci were discovered for marker development in the crop. Our draft genome of an Indian black gram provides the foundational genomic resources for the improvement of important agronomic traits and ultimately will help in accelerating black gram breeding programs.</p>
Microbiome network connectivity and composition linked to disease resistance in strawberry plants
<p>The two R data files correspond phyloseq objects used in the study. The file phyloseq_nochim_silva.RData and phyloseq_nochim_unite.RData correspond to bacterial and fungal phyloseq objects, respectively. Both objects include count table, taxonomy table and metadata information. </p>
Fig 1 in Tail and fin rot disease and antibiotics resistance pattern in major rainbow trout farms of Nepal
Fig 1: Survey and Sample Collection site
Assessment of animal diseases caused by bacteria resistant to antimicrobials: Dogs and cats - Appendix B: Excel file with all data extracted
<p>Information on all the full-text studies that were assessed, including the reason for exclusion for those that were excluded at the full-text screening and the data extracted from the included studies, can be consulted here. </p> <p>The extensive literature review was carried out by the University of Copenhagen under the contract OC/EFSA/ALPHA/2020/02 – LOT 1 (https://ted.europa.eu/udl?uri=TED:NOTICE:457654-2020:TEXT:EN:HTML)</p>
Assessment of animal diseases caused by bacteria resistant to antimicrobials: Horses - Appendix B: Excel file with all data extracted
<p>Information on all the full-text studies that were assessed, including the reason for exclusion for those that were excluded at the full-text screening and the data extracted from the included studies, can be consulted here. </p> <p>The extensive literature review was carried out by the University of Copenhagen under the contract OC/EFSA/ALPHA/2020/02 – LOT 1 (https://ted.europa.eu/udl?uri=TED:NOTICE:457654-2020:TEXT:EN:HTML)</p>
Durable resistance or efficient disease control? Adult Plant Resistance (APR) at the heart of the dilemma [Dataset]
<p>Dataset of simulation results used in this study (https://doi.org/10.24072/pcjournal.271):</p> <p><strong>Durable resistance or efficient disease control? Adult Plant Resistance (APR) at the heart of the dilemma.</strong></p> <p>published in Peer Community Journal.</p> <p> </p> <p>All simulations are computed using the R package landsepi<br> Package webpage: https://csiro-inra.pages.biosp.inrae.fr/landsepi/<br> To download the package: https://cran.r-project.org/web/packages/landsepi/index.html</p> <p>Raw data used for this study are stored in three folders corresponding to<br> the three numerical experiments (APR_1, APR_2 and APR_3, respectively).</p> <p>Every folder includes:<br> - an R script for the generation of a simulation plan<br> - 10 folders containing simulation results for 10 stochastic replicates<br> - an R script for the analysis of the results and generation of graphics</p> <p>Every folder containing the simulation results includes:<br> - a text file "myDesign.txt" containing the simulation plan and outputs (1 line per simulation)<br> - a text file "parameters.txt" containing a summary of all parameter values<br> - a text file "param_disp_patho.txt" containing the dispersal matrix of the pathogen<br> - a text file "param_landscape.txt" containing the landscape structure<br> (i.e. for every polygon [lines] and every year [columns] the index of the cultivated host)</p>
Genomic Signatures of Disease Resistance in Endangered Staghorn Corals
<p>White Band Disease (WBD) has caused unprecedented declines in the Caribbean <em>Acropora</em> corals, which are now listed as critically endangered species. Highly disease resistant <em>Acropora</em> <em> cervicornis</em> genotypes exist, but we lack understanding of the genetic underpinnings of disease resistance. Using transmission experiments, a newly assembled genome, and whole genome resequencing of 76 <em>A. cervicornis</em> genotypes from Florida and Panama, we identified ten genomic regions and 73 single-nucleotide polymorphisms (SNPs) that are strongly associated with disease resistance and that include functional, protein coding changes in four genes involved in coral immunity and pathogen detection. Polygenic scores calculated from 10 genomic loci indicate that simple genetic screens can predict <em>A. cervicornis</em> disease resistance and that adaptive polygenic variation can be used to improve disease resistance in wild and nursery stocks of <em>A. cervicornis</em> across the Caribbean.</p>
A Double-blind Comparative Study of the Efficacy and Safety of E3810 10mg Once and Twice Daily in Maintenance Therapy for PPI Resistant Gastroesophageal Reflux Disease Patients
ClinicalTrials.gov study NCT02135107. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Insulin Resistance in Non-alcoholic Fatty Liver Disease
ClinicalTrials.gov study NCT00252499. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Effect of Pioglitazone on Insulin Resistance, Atherosclerosis Progression and Clinical Course of Coronary Heart Disease
ClinicalTrials.gov study NCT03011775. IPD Sharing: NO. Countries: 1. Publications: 1.
Role of Endorphins in Perception of Dyspnea With Resistive Loading in Chronic Obstructive Pulmonary Disease (COPD)
ClinicalTrials.gov study NCT00958919. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Insulin Resistance in Non-alcoholic Fatty Liver Disease
ClinicalTrials.gov study NCT01289639. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Tumor Necrosis Factor Inhibition in Focal Segmental Glomerulosclerosis and Treatment Resistant Minimal Change Disease
ClinicalTrials.gov study NCT04009668. IPD Sharing: YES. Countries: 1. Publications: 1.
Aspirin Resistance in Coronary Artery Disease
ClinicalTrials.gov study NCT00753935. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Clinical Trial of Anakinra for Steroid-Resistant Autoimmune Inner Ear Disease
ClinicalTrials.gov study NCT01267994. IPD Sharing: Not stated. Countries: 1. Publications: 1.
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.