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ShareScore release 0.9.0
Dataset results
38 results for “environmental contamination”
Data from: Evolution to environmental contamination ablates the circadian clock of an aquatic sentinel species
Environmental contamination is a common cause of rapid evolution. Recent work has shown that Daphnia pulex, an important freshwater species, can rapidly evolve increased tolerance to a common contaminant, sodium chloride (NaCl) road salt. While such rapid evolution can benefit organisms, allowing them to adapt to new environmental conditions, it can also be associated with unforeseen tradeoffs. Given that exposure to environmental contaminants can cause circadian disruption, we investigated whether the circadian clock was affected by evolving a tolerance to high levels of road salt. By tracking the oscillations of a putative clock gene, period, we demonstrated that D. pulex express per mRNA with approximately 20-hour oscillations under control conditions. This putative circadian rhythm was ablated in response to high levels of salinity; populations adapted to high NaCl concentrations exhibited an ablation of period oscillation. Moreover, we showed that while gene expression is increased in several other genes, including clock, actin, and Na+/K+-ATPase, upon the adaptation to high levels of salinity, per expression is unique among the genes we tracked in that it is the only gene repressed in response to salt adaptation. These results suggest that rapid evolution of salt tolerance occurs with the tradeoff of suppressed circadian function. The resultant circadian disruption may have profound consequences to individuals, populations, and aquatic food webs by affecting species interactions. In addition, our research suggests that circadian clocks may also be disrupted by the adaptation to other environmental contaminants.
Fig. 3 in Factors that alter the biochemical biomarkers of environmental contamination in Chironomus sancticaroli (Diptera, Chironomidae)
Fig. 3. Effect of sample freezing on the activity of acetylcholinesterase (AChE), alpha esterase (EST-α), and beta alpha esterase (EST-β) of Chironomus sancticaroli. The values are expressed as the mean value of enzyme activity ± SD (n = 30 for each condition). Different letters indicate significant differences when p <0.05 (using paired t-test).
Assessing and Addressing Community Exposures to Environmental Contaminants
ClinicalTrials.gov study NCT06315140. IPD Sharing: YES. Countries: 1. Publications: 0.
Data from: Evolution to environmental contamination ablates the circadian clock of an aquatic sentinel species
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Early life exposure to environmental contaminants (BDE-47, TBBPA, and BPS) produced persistent gut dysbiosis in adult male mice
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Data from: Environmental context and contaminant biotransport by Pacific salmon interact to mediate the bioaccumulation of contaminants by stream-resident fish
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Effects of cross-fostering and developmental exposure to mixtures of environmental contaminants on hepatic gene expression in prepubertal 21 days old and adult male Sprague-Dawley rats IV.
GEO Series GSE109016. Rattus norvegicus. 16 samples. Type: Expression profiling by array.
Effects of cross-fostering and developmental exposure to mixtures of environmental contaminants on hepatic gene expression in prepubertal 21 days old and adult male Sprague-Dawley rats
GEO Series GSE109019. Rattus norvegicus. 72 samples. Type: Expression profiling by array.
Effects of cross-fostering and developmental exposure to mixtures of environmental contaminants on hepatic gene expression in prepubertal 21 days old and adult male Sprague-Dawley rats II.
GEO Series GSE109014. Rattus norvegicus. 16 samples. Type: Expression profiling by array.
Effects of cross-fostering and developmental exposure to mixtures of environmental contaminants on hepatic gene expression in prepubertal 21 days old and adult male Sprague-Dawley rats VI.
GEO Series GSE109018. Rattus norvegicus. 8 samples. Type: Expression profiling by array.
Effects of cross-fostering and developmental exposure to mixtures of environmental contaminants on hepatic gene expression in prepubertal 21 days old and adult male Sprague-Dawley rats V.
GEO Series GSE109017. Rattus norvegicus. 16 samples. Type: Expression profiling by array.
Effects of cross-fostering and developmental exposure to mixtures of environmental contaminants on hepatic gene expression in prepubertal 21 days old and adult male Sprague-Dawley rats I
GEO Series GSE109013. Rattus norvegicus. 8 samples. Type: Expression profiling by array.
Epigenetic Programming Alterations in Alligators from Environmentally Contaminated Lakes
GEO Series GSE82318. Alligator mississippiensis. 4 samples. Type: Methylation profiling by genome tiling array.
Effects of cross-fostering and developmental exposure to mixtures of environmental contaminants on hepatic gene expression in prepubertal 21 days old and adult male Sprague-Dawley rats III.
GEO Series GSE109015. Rattus norvegicus. 8 samples. Type: Expression profiling by array.
Discovering Cancer Risks From Environmental Contaminants and Maternal/Child Health
ClinicalTrials.gov study NCT05746169. IPD Sharing: NO. Countries: 1. Publications: 0.
Intervention to Reduce Exposure to Environmental COntaminant (IRECO)
ClinicalTrials.gov study NCT04919434. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Impact of Enhanced Daily Disinfection on Environmental Contamination in Hospital Rooms
ClinicalTrials.gov study NCT05739955. IPD Sharing: NO. Countries: 1. Publications: 0.
Toxicity of Micro and Nano Plastics Combined With Environmental Contaminants on the Risk of Allergic Disease
ClinicalTrials.gov study NCT05177744. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.