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datasets available to search
ShareScore release 0.9.0
Dataset results
35 results for “environmental pollutant”
Environmental Pollutants and Life Quality
ClinicalTrials.gov study NCT06591988. IPD Sharing: NO. Countries: 1. Publications: 0.
Occupational Exposure of Firefighters to Environmental Pollutants
ClinicalTrials.gov study NCT05256212. IPD Sharing: YES. Countries: 1. Publications: 0.
Measuring Environmental Tobacco and Cannabis: Pollutants and Exposures
ClinicalTrials.gov study NCT06030674. IPD Sharing: NO. Countries: 1. Publications: 0.
Environmental Pollutants and the Risk of Soft Tissue Sarcoma: A Pilot Study
ClinicalTrials.gov study NCT00611078. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Clinical Study of the Effects of Environmental Pollution on Obesity
ClinicalTrials.gov study NCT06670703. IPD Sharing: NO. Countries: 1. Publications: 0.
Correlation Between Environmental Pollution and Gestational Diabetes Mellitus
ClinicalTrials.gov study NCT05388721. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Infant Sleep and Exposure to Mixture of Chemical Environmental Pollutants
ClinicalTrials.gov study NCT06268444. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Environmental Pollutants and Neurological Disorders
ClinicalTrials.gov study NCT07140601. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Temporal Transcriptomic Analysis of Human Primary Keratinocytes Exposed to β-naphthoflavone Highlights the Protective Efficacy of Skin to Environmental Pollutants
GEO Series GSE143748. Homo sapiens. 6 samples. Type: Expression profiling by array.
The Effect of Environmental Pollution on Colorectal Cancer
ClinicalTrials.gov study NCT06686953. IPD Sharing: NO. Countries: 0. Publications: 0.
The Effect of Environmental Pollution on the Prognosis of Gastric Cancer
ClinicalTrials.gov study NCT06686966. IPD Sharing: NO. Countries: 0. Publications: 0.
Environmental Pollutant Induced Epigenetic Predisposition to Developmental Defects and Cancer Phenotypes in the Progeny
GEO Series GSE111834. Drosophila melanogaster. 4 samples. Type: Expression profiling by high throughput sequencing.
Genomic and physiological responses to strong selective pressure during late organogenesis: how natural Fundulus heteroclitus populations cope with persistent environmental pollution Superfund Site
GEO Series GSE47654. Fundulus heteroclitus. 48 samples. Type: Expression profiling by array.
Gonadal gene expression in a fish with genetic and environmental sex determination under thermal and chemical pollution
GEO Series GSE52938. Dicentrarchus labrax. 10 samples. Type: Expression profiling by array.
Prenatal exposure to environmental air pollution and psychosocial stress jointly contribute to the epigenetic regulation of the serotonin transporter gene in newborns
<p>This database includes the raw data linked with the paper “Prenatal exposure to environmental air pollution and psychosocial stress jointly contribute to the epigenetic regulation of the serotonin transporter gene in newborns” accepted for publication on Molecular Psychiatry. This study is part of the longitudinal and multi-centric “Measuring the outcomes of maternal COVID-19-related prenatal exposure (MOM-COPE)” study. Here, we report on the interactive influence of variations in antenatal exposures to maternal pandemic-related stress (PRS) and PM2.5 on SLC6A4 DNAm levels in newborns.</p> <p>Procedures</p> <p>Mother–infant dyads (N=307) were enrolled at delivery during the COVID-19 pandemic. Infants’ methylation status was assessed in 13 CpG sites within the SLC6A4 gene’s region (chr17:28562750–28562958) in buccal cells at birth and women retrospectively report on PRS. PM2.5 exposure throughout the entire gestation and at each gestational trimester was estimated using a spatiotemporal model based on residential address.</p> <p> </p> <p>Among several potentially confounding socio-demographic and health-related factors, infant’s sex was significantly associated with infants’ SLC6A4 DNAm levels, thus hierarchical regression models were adjusted for infant’s sex.</p> <p>Mother–infant dyads (N = 276) were recruited at delivery. Maternal trait anxiety, as a marker of antenatal chronic stress exposure, was assessed soon after delivery using the Stait-Trait Anxiety Inventory (STAI-Y). Infants’ BDNF DNAm at birth was assessed in 11 CpG sites in buccal cells whereas infants’ NE was assessed at 3 (N = 225) and 6 months (N = 189) using the Infant Behavior Questionnaire-Revised (IBQ-R).</p> <p>Analytical plan</p> <p>Principal component analysis (PCA) was used to reduce the number of CpG sites into a smaller set of factors.</p> <p>A four-factor solution, where the targeted CpG sites were aggregated in 4 main factors, showed the best fit to the data (Table 2). Principal Component 1 (PC1; composed of 6 CpG sites) and Principal Component 2 (PC2; composed of 3 CpG sites) accounted, respectively, for 31.6% and 12.8% of the total variance in SLC6A4 DNAm and were used in further analyses. Pearson correlations and independent samples t-tests were employed to explore the potential effect of sociodemographic and health-related variables on infant methylation levels. All variables found to be significantly associated with the outcomes examined were included as covariates in subsequent analyses. Separate hierarchical regression analyses were performed to evaluate the independent and interactive effects of maternal PRS and exposure to air pollution on infant methylation levels.</p> <p>Findings in brief</p> <p>Higher levels of SLC6A4 DNAm at 6 CpG sites were found in newborns born to mothers reporting higher levels of antenatal PRS and greater PM2.5 exposure across gestation, while adjusting for infant’s sex. These effects were especially evident when exposure to elevated PM2.5 occurred during the second trimester of pregnancy.</p>
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.