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Dataset results
821 results for “epigenetic regulation”
Epigenetic Regulation of BDNF in Major Depression
ClinicalTrials.gov study NCT01182103. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Paliperidone and Lithium in the Treatment of Suicidality - Treatment Indication and Epigenetic Regulation
ClinicalTrials.gov study NCT01134731. IPD Sharing: NO. Countries: 1. Publications: 0.
Epigenetic regulation of autonomous pathway mediates polymorphism of flowering time in Arabidopsis
Open the record for dataset details and reuse information.
Characterization of Epigenetic Regulation in an Extraterrestrial Environment: The Arabidopsis Spaceflight Methylome [RNA-seq]
When germinated and grown on-board the ISS (International Space Station) plant do not exhibit abnormal structures but they do have altered growth habits and this project aims to investigate the molecular mechanisms that provide the foundation for the altered growth habits observed in orbit. APEX03-2 (Advanced Plant Experiment 03-2) also known as TAGES-ISA (Transgenic Arabidopsis Gene Expression System-Intracellular Signaling Architecture) specifically addresses the growth and molecular changes that occur in Arabidopsis thaliana plants during spaceflight by using molecular and genetic tools and by asking fundamental questions regarding root structure growth and cell wall remodeling may be answered. This investigation advances the fundamental understanding of the molecular biological responses to extraterrestrial environments. This understanding helps to further define the impacts of spaceflight on biological systems to better enable NASA xc3 xaf xc2 xbf xc2 xbds future space exploration goals.
Characterization of Epigenetic Regulation in an Extraterrestrial Environment: The Arabidopsis Spaceflight Methylome [Bisulfite-seq]
When germinated and grown on-board the ISS (International Space Station) plant do not exhibit abnormal structures but they do have altered growth habits and this project aims to investigate the molecular mechanisms that provide the foundation for the altered growth habits observed in orbit. APEX03-2 (Advanced Plant Experiment 03-2) also known as TAGES-ISA (Transgenic Arabidopsis Gene Expression System-Intracellular Signaling Architecture) specifically addresses the growth and molecular changes that occur in Arabidopsis thaliana plants during spaceflight by using molecular and genetic tools and by asking fundamental questions regarding root structure growth and cell wall remodeling may be answered. This investigation advances the fundamental understanding of the molecular biological responses to extraterrestrial environments. This understanding helps to further define the impacts of spaceflight on biological systems to better enable NASA x92s future space exploration goals.
KDM6A Epigenetically Regulates Subtype Plasticity in Small Cell Lung Cancer.
GEO Series GSE215829. Mus musculus. 26 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Epigenetic regulation of the MEG3-DLK1 microRNA cluster in human Type 2 diabetic islets
GEO Series GSE52314. Homo sapiens. 12 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Integrative omics analyses reveal epigenetic memory in diabetic cells regulating genes associated with kidney dysfunction. [sequencing]
GEO Series GSE145746. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Comprehensive analyses of partially methylated domains and differentially methylated regions in esophageal cancer reveal both cell-type- and cancer-specific epigenetic regulation [WGBS]
GEO Series GSE210218. Homo sapiens. 2 samples. Type: Methylation profiling by high throughput sequencing.
METTL7B is an essential epigenetic regulator of lineage specification in glioblastoma
GEO Series GSE243132. Homo sapiens. 73 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by genome tiling array.
Epigenetic regulation of cell state by H2AFY governs immunogenicity in high-risk neuroblastoma [CUT&RUN]
GEO Series GSE270196. Mus musculus. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells
GEO Series GSE119466. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
The WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape
GEO Series GSE178677. Mus musculus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
A single-cell transcriptomics CRISPR-activation screen identifies new epigenetic regulators of the zygotic genome activation programm (10X Genomics CRISPRa screen dataset)
GEO Series GSE135621. Mus musculus. 27 samples. Type: Expression profiling by high throughput sequencing.
Integrated Multiomic Profiling Identifies the Epigenetic Regulator PRC2 as a Therapeutic Target to Counteract Leukemia Immune Escape and Relapse [ATAC-seq]
GEO Series GSE197416. Homo sapiens. 32 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
CRISPR-based epigenome editing screens identify transcriptional and epigenetic regulators of human CD8 T cell function [Sorting-based CRISPR screens]
GEO Series GSE241933. Homo sapiens. 40 samples. Type: Other.
Novel Isoforms of the Epigenetic Regulator TET1 Differentially Control CNS Synaptic Function, Plasticity, and Cognition
GEO Series GSE140174. Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Epigenetic regulation of profibrotic macrophages in systemic sclerosis- associated interstitial lung disease
GEO Series GSE212109. Homo sapiens. 17 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
The relative importance of DNA methylation and Dnmt2-mediated epigenetic regulation on Wolbachia densities and cytoplasmic incompatibility
GEO Series GSE63795. Drosophila melanogaster. 2 samples. Type: Methylation profiling by high throughput sequencing.
Targeting epigenetic regulators to overcome drug resistance in the emerging human fungal pathogen Candida auris
GEO Series GSE293594. Candidozyma auris. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.