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206
datasets available to search
ShareScore release 0.9.0
Dataset results
206 results for “epitope”
Monoclonal antibodies from humans with Mycobacterium tuberculosis exposure or latent infection recognize distinct arabinomannan epitopes
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Protective antibodies target cryptic epitope unmasked by cleavage of malaria sporozoite protein
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Data from: SUB-immunogold-SEM reveals nanoscale distribution of submembranous epitopes
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Profiling of linear B-cell epitopes against human coronaviruses in pooled sera sampled early in the COVID-19 pandemic
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Converting non-neutralizing SARS-CoV-2 antibodies targeting conserved epitopes into broad-spectrum inhibitors through receptor blockade
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Data from: Liquid chromatography-mass spectrometry (LC-MS) data of a multi-epitope peptibody with bFGF/VEGFA
<p><span><span><span><span><span><span><span><span><span><span><span>The <span><span><span>protein </span></span></span><span><span><span>primary </span></span></span><span><span><span>structure of the recombinant </span></span></span>Peptibody were investigated systematically by Liquid Chromatography-Mass Spectrometry (LC-MS)<span><span><span>. T</span></span></span><span><span>he 15 amino acids of N-terminal were </span></span>Met-Gln-Lys-Arg-Lys-Arg-Lys-Lys-Ser-Arg-Tyr-Lys-Ser-Gly-Gly and <span><span>the C-terminal was Lys (K</span></span><span><span>), the same as</span></span> the theoretical sequence. <span><span>With more </span></span><a><span class="15"><span>protease</span></span></a><span><span>s, the whole sequence was detected at the coverage of </span></span>trypsin 87.5%, <span><span>c</span></span><span><span>hymotrypsin</span></span> 75.3% and <span><span>Glu-C</span></span> 76.7%<span><span>. The </span></span>peptide-mapping could be used as an valuable standard to certify the complete expression and primary structure of Peptibody. The pI and MW were 8.93 and 37.415 kDa, within the errors allowed . The binding specificity after production were analyzed using anti-VEGFA and anti-His antibodies.</span></span></span></span></span></span></span></span></span></span></span></p>
Computational epitope map of SARS-CoV-2 spike protein
<p>Dataset accompanying the publication "Map of SARS-CoV-2 spike epitopes not shielded byglycans" published in XYZ.</p> <p> </p> <p>The dataset contains:</p> <p>1. raw epitope screening scores (README file attached in the archive)</p> <p>2. structure and GROMACS topology and input files for two systems:</p> <p> - 4x SARS-CoV-2 spike protein, glycosylated<br> - 4x SARS-CoV-2 spike protein, non-glycosylated</p> <p> </p>
WT1 targeting multi-epitope vaccine design for glioblastoma multiforme using immuno-informatics approaches
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Dataset: Predicting T Cell Receptor Functionality against Mutant Epitopes
<p>This upload contains the Datasets and Supplementary Material for "Predicting T Cell Receptor Functionality against Mutant Epitopes" (DOI: https://doi.org/10.1101/2023.05.10.540189) by Felix Drost, Emilio Dorigatti, Adrian Straub, Philipp Hilgendorf, Karolin I. Wagner, Kersten Heyer, Marta López Montes, Bernd Bischl, Dirk H. Busch, Kilian Schober, and Benjamin Schubert.</p>
Epitope dataset
<p>Dataset of experimentally validated epitopes targeted by neutralizing antibodies located in the SARS-CoV-2 spike protein, retrieved from IEDB (https://www.iedb.org/).</p>
SARA module 3: NGS epitope sequencing: Illumina FASTQ files
<p>We investigate the accumulated microbial and autoantigen antibody repertoire in adult-onset dermatomyositis patients sero-positive for TIF1γ (TRIM33) autoantibodies. We use an untargeted high-throughput approach which combines immunoglobulin disease-specific epitope-enrichment and identification of microbial and human antigens. We observe antibodies recognizing a wider repertoire of microbial antigens in dermatomyositis. Antibodies recognizing viruses and Poxviridae family species are significantly enriched. The identified autoantibodies recognise a large portion of the human proteome, including interferon regulated proteins; these proteins cluster in specific biological processes. In addition to TRIM33, we identify autoantibodies against eleven further TRIM proteins, including TRIM21. Some of these TRIM proteins share epitope homology with specific viral species including poxviruses. Our data suggest antibody accumulation in dermatomyositis against an expanded diversity of microbial and human proteins and evidence of non-random targeting of specific signalling pathways. Our findings indicate that molecular mimicry and epitope spreading events may play a role in dermatomyositis pathogenesis.</p>
In silico Antibody-Peptide Epitope prediction for Personalized cancer therapy publication data
<p>In silico Antibody-Peptide Epitope prediction for Personalized cancer therapy publication data</p>
Safety and Efficacy Study of Epitope Peptide To Treat HLA-A*24 Disease Controlled Advanced Non-small Cell Lung Cancer
ClinicalTrials.gov study NCT01950156. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Safety Study of Cancer Specific Epitope Peptides Cocktail for Cervical, GI, and Lung Tumors
ClinicalTrials.gov study NCT00676949. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Blood Collection Study From COVID-19 Convalescents Previously Hospitalized to Identify Immunogenic Viral Epitopes
ClinicalTrials.gov study NCT04397900. IPD Sharing: NO. Countries: 1. Publications: 5.
To Identify HLA-A1101-restricted Peptide Epitopes Derived From Novel Oncoantigens (URLC10, KIF20A, and CDCA1) Applicable for Cancer Vaccine in Singapore
ClinicalTrials.gov study NCT01570439. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Combination of Chemoradiation Therapy and Epitope Peptide Vaccine Therapy in Treating Patients With Esophageal Cancer
ClinicalTrials.gov study NCT00632333. IPD Sharing: Not stated. Countries: 1. Publications: 13.
Safety and Efficacy Study of Epitope Peptide To Treat HLA-A*02 Disease Controlled Advanced Non-small Cell Lung Cancer
ClinicalTrials.gov study NCT01949701. IPD Sharing: Not stated. Countries: 1. Publications: 5.
SARA module 3: NGS epitope sequencing: Illumina FASTQ files
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Data from: Liquid chromatography-mass spectrometry (LC-MS) data of a multi-epitope peptibody with bFGF/VEGFA
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ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.