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257 results for “exome”
REVEL (Rare Exome Variant Ensemble Learner) Scores
<p>REVEL is an ensemble method for predicting the pathogenicity of missense variants in the human genome. For more information, see <a href="https://sites.google.com/site/revelgenomics/">https://sites.google.com/site/revelgenomics/</a> and <a href="https://dx.doi.org/10.1016/j.ajhg.2016.08.016">https://dx.doi.org/10.1016/j.ajhg.2016.08.016</a>.</p>
Exome sequence analysis identifies rare coding variants associated with a machine learning-based marker for coronary artery disease.
<p>*.sh and *.R are codes to test rare coding variants for association with ISCAD.</p> <p>Petrazzini_etal_2024_*_level_meta_analysis.txt.gz are summary statistics of variant- and gene-level associations of rare coding variants in the exome sequences of 604,914 individuals with an in-silico score for coronary artery disease (ISCAD).</p> <p>Chromosomal positions are mapped to the GRCh38 (hg38) human genome reference.</p> <p>Directions of effect correspond to associations in the UK Biobank, the All of Us Research Program, the BioMe Biobank sample 1 and the BioMe Biobank sample 2, in that order.</p>
Screen of A6 TCR against a library of HLA-A*02:01 MHC-I peptides from the human exome
<p>T2 cells expressing a library of off targets (derived from A6 and B7 binding motifs in Hausmann 1999) are co-cultured with A6, DMF5 or 1G4 expressing T cells (from a non-A2 donor) and minigenes from surviving cells are amplified.</p>
Screen of A6 and B7 TCR against a library of HLA-A*02:01 MHC-I peptides from the human exome
<p>T2 cells expressing a library of off targets (derived from A6 and B7 binding motifs in Hausmann 1999) are co-cultured with A6, B7. DMF5 or 1G4 expressing T cells (from a non-A2 donor) and minigenes from surviving cells are amplified.</p>
Analysis results for association study of long-term kidney transplant rejection using whole-exome sequencing
<p>Association study results for long-term kidney transplant rejection. Single-variant association results are provided as Plink output files. Meta-analysis results are provided as METAL output files. FDR results are sorted lists of the top association result from random sample label permutations and are included with the plink and meta-analysis results. SKAT and GSEA results are provided for gene and pathway level analyses, respectively.</p>
Screen of A6,B7,1G4 TCRs against a library of HLA-A*02:01 MHC-I peptides from the human exome
<p>T2 cells expressing a library of off targets (derived from A6 and B7 binding motifs in Hausmann 1999) are co-cultured with A6, B7 or1G4 expressing T cells (from a non-A2 donor). Minigenes from surviving cells are amplified and sequenced.</p>
Data files for manuscript "Exome first approach to reduce diagnostic costs and time – retrospective analysis of 111 individuals with rare neurodevelopmental disorders"
<p>#2021-07-23<br> #Summary<br> This ZIP-file contains the Excel files used for the clinical and variant analyses for the manuscript "Exome first approach to reduce diagnostic costs and time – retrospective analysis of 111 individuals with rare neurodevelopmental disorders".</p> <p>#Folder structure<br> ./ (parent directory containing this README file and all subfolders)<br> ./Clinical/ (contains an Excel sheets with complete clinical data, costs and criteria)<br> ./Variants/ (contains an Excel sheet with all variant annotation)</p> <p>#Files and checksums<br> 6DB0EF10BE7A7AF5A18E523F33FB662A ./Clinical/FileS2_Clinical.xlsx<br> 0B0C1AFA0751B63A35DC99DB25546A38 ./Variants/FileS3_Variants.xlsx</p>
Exome sequencing of a hybrid pine species complex on the Qinghai-Tibetan Plateau
<p>This study investigates the evolutionary history of <em>Pinus</em> <em>densata</em> on the Qinghai-Tibetan Plateau (QTP) and genomic heterogeneity across a zone of species transition to understand contemporary dynamics of selection and evolution of species barriers. We analyzed the genetic diversity in a range-wide collection of <em>P. densata</em> and representative populations of its progenitors <em>P. tabuliformis</em> and <em>P. yunnanensis</em> using 40,000 exome probe capture sequencing.</p>
Wheat pan exome panel
<p>Tcuni wheat pan exome panel v2.0 (WheatPanExomeV2) was based on multiple wheat genomes(Chinese Spring RefSeq V2.1, KN9204, AK58 ect..). </p>
Enabling Personalized Medicine Through Exome Sequencing in the U.S. Air Force
ClinicalTrials.gov study NCT03276637. IPD Sharing: UNDECIDED. Countries: 1. Publications: 18.
North Carolina Newborn Exome Sequencing for Universal Screening
ClinicalTrials.gov study NCT02826694. IPD Sharing: YES. Countries: 1. Publications: 1.
NCGENES: North Carolina Clinical Genomic Evaluation by NextGen Exome Sequencing
ClinicalTrials.gov study NCT01969370. IPD Sharing: YES. Countries: 1. Publications: 1.
Clinical Utility of Prenatal Whole Exome Sequencing
ClinicalTrials.gov study NCT03482141. IPD Sharing: NO. Countries: 1. Publications: 6.
North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2
ClinicalTrials.gov study NCT03548779. IPD Sharing: YES. Countries: 1. Publications: 61.
Clinical Utility of Pediatric Whole Exome Sequencing
ClinicalTrials.gov study NCT03525431. IPD Sharing: NO. Countries: 1. Publications: 3.
Data from: Exome resequencing reveals signatures of demographic and adaptive processes across the genome and range of black cottonwood (Populus trichocarpa)
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Whole exome sequencing reveals a long-term decline in effective population size of red spruce (Picea rubens)
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Exome capture design for the strawberry poison frog, Oophaga pumilio, in Bocas del Toro
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Exome sequencing of a hybrid pine species complex on the Qinghai-Tibetan Plateau
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Exome capture of Antarctic krill (Euphausia superba) for cost effective genotyping and population genetics with historical collections
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.