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Dataset results
189 results for “immobilization”
Efficient improvement of the proliferation, differentiation, and anti-arthritic capacity of mesenchymal stem cells by simply culturing on the immobilized FGF2 derived peptide, 44-ERGVVSIKGV-53
<p>All data needed to evaluate the results presented in the paper: Soo Bin Lee, Ahmed Abdal Dayem, Sebastian Kmiecik, Kyung Min Lim, Dong Sik Seo, Hyeong-Taek Kim, Polash Kumar Biswas, Minjae Do, Deok-Ho Kim, Ssang-Goo Cho, Efficient improvement of the proliferation, differentiation, and anti-arthritic capacity of mesenchymal stem cells by simply culturing on the immobilized FGF2 derived peptide, 44-ERGVVSIKGV-53,<br>Journal of Advanced Research, Volume 62,<br>2024,<br>Pages 119-141,<br>ISSN 2090-1232,<br>https://doi.org/10.1016/j.jare.2023.09.041.</p>
Data and code for "Brehm et al. (2023) The complexity of micro- and nanoplastic research in the genus Daphnia – A systematic review of study variability and a meta-analysis of immobilization rates"
<p>All data and R code for</p> <p><strong>Brehm, J., Ritschar, S., Laforsch, C. and Mair, M.M. (2023). The complexity of micro- and nanoplastic research in the genus <em>Daphnia</em> – A systematic review of study variability and a meta-analysis of immobilization rates. <em>Journal of Hazardous Materials</em> 458: 131839. (<a href="https://doi.org/10.1016/j.jhazmat.2023.131839">https://doi.org/10.1016/j.jhazmat.2023.131839</a>)</strong></p> <p><em>Abstract</em></p> <p>In recent years, the number of publications on nano- and microplastic particles (NMPs) effects on freshwater organisms has increased rapidly. Freshwater crustaceans of the genus <em>Daphnia</em> are widely used in ecotoxicological research as model organisms for assessing the impact of NMPs. However, the diversity of experimental designs in these studies makes conclusions about the general impact of NMPs on <em>Daphnia</em> challenging. To approach this, we systematically reviewed the literature on NMP effects on <em>Daphnia</em> and summarized the diversity of test organisms, experimental conditions, NMP properties and measured endpoints to identify gaps in our knowledge of NMP effects on <em>Daphnia</em>. We use a meta-analysis on mortality and immobilization rates extracted from the compiled literature to illustrate how NMP properties, study parameters and the biology of <em>Daphnia</em> can impact outcomes in toxicity bioassays. In addition, we investigate the extent to which the available data can be used to predict the toxicity of untested NMPs based on the extracted parameters. Based on our results, we argue that focusing on a more diverse set of NMP properties combined with a more detailed characterization of the particles in future studies will help to fill current research gaps, improve predictive models and allow the identification of NMP properties linked to toxicity.</p>
Short Forearm Casting Versus Below-elbow Splinting for Acute Immobilization of Distal Radius Fractures
ClinicalTrials.gov study NCT02679066. IPD Sharing: NO. Countries: 1. Publications: 5.
Comparing Two Forms of Head Immobilization for Stereotactic Radiotherapy
ClinicalTrials.gov study NCT00328510. IPD Sharing: Not stated. Countries: 1. Publications: 3.
The role of substrate in determining the dominance of immobile, epifaunal bivalves in the Late Cretaceous
Open the record for dataset details and reuse information.
Enhanced Heterogenous Hydration of SO2 Through Immobilization of Pyridinic-N on Carbon Materials
Carbon materials doped with nitrogen has long been utilized for SO2 removal from flue gases for the benefits of environment. The role of water is generally regarded as hydration of SO3 which is formed through the oxidization of SO2. However, the hydrolysis of SO2, especially on the surface of N doped carbon materials, was almost ignored. In this study, the hydrolysis of SO2 was investigated in detail on the pyridinic nitrogen (PyN) doped graphene (GP) surfaces. It is found that, compared to the homogenous hydrolysis of SO2 assisted with NH3 in gas phase, the heterogeneous hydrolysis is much more thermodynamically and kinetically favorable. Specifically, when a single H2O molecule is involved, the energy barrier for SO2 hydrolysis is as low as 0.15 eV, with 0.59 eV released, indicating the hydrolysis of SO2 can occur at rather low water concentration and temperature. Thermodynamic integration molecular dynamics results show the feasibility of the hydrogenated substrate recovery and the immobilized N acting as a catalytic site for SO2 hydrolysis. Our findings show that the heterogeneous hydrolysis of SO2 should be universal and potentially uncover the puzzling reaction mechanism for SO2 catalytic oxidation at low temperature by N doped carbon materials.
The Alginate Immobilization of Metabolic Enzymes (AIME) platform retrofits an estrogen receptor transactivation assay with metabolic competence
The U.S. EPA Endocrine Disruptor Screening Program utilizes data across the ToxCast/Tox21 high-throughput screening (HTS) programs to evaluate the biological effects of potential endocrine active substances (EAS). A potential limitation to the use of in vitro assay data in regulatory decision-making is the lack of coverage for xenobiotic metabolic processes. Both hepatic- and peripheral-tissue metabolism can yield metabolites that exhibit greater activity than the parent compound (bioactivation) or are inactive (bioinactivation) for a given biological target. Interpretation of biological effect data for both putative EAS, as well as other chemicals, screened in HTS assays may benefit from the addition of xenobiotic metabolic capabilities to decrease the uncertainty in predicting potential hazards to human health. The objective of this study was to develop an approach to retrofit existing HTS assays with hepatic metabolism. The Alginate Immobilization of Metabolic Enzymes (AIME) platform encapsulates hepatic S9 fractions in alginate microspheres attached to 96-well peg lids. Functional characterization across a panel of reference substrates for phase I cytochrome P450 enzymes revealed substrate depletion with expected metabolite accumulation. Performance of the AIME method in the VM7Luc estrogen receptor (ER) transactivation assay was evaluated across 15 reference chemicals and 48 test chemicals that yield metabolites previously identified as ER active or inactive. The results demonstrate the utility of applying the AIME method for identification of false positive and false negative target assay effects, reprioritization of hazard based on metabolism-dependent bioactivity, and enhanced in vivo concordance with the rodent uterotrophic bioassay. Integration of the AIME metabolism method may prove useful for future biochemical and cell-based HTS applications.
Data for: Immobilization of molecular catalysts on electrode surfaces using host–guest interactions
<p>Anchoring molecular catalysts on electrode surfaces combines the high selectivity and activity of molecular systems with the practicality of heterogeneous systems. Molecular catalysts, however, are far less stable than traditional heterogeneous electrocatalysts, and therefore a method to easily replace anchored molecular catalysts that have degraded could make such electrosynthetic systems more attractive. Here, we apply a non-covalent 'click' chemistry approach to reversibly bind molecular electrocatalysts to electrode surfaces through host–guest complexation with surface-anchored cyclodextrins. The host–guest interaction is remarkably strong and enables the flow of electrons between the electrode and the guest catalyst. Electrosynthesis in both organic and aqueous media was demonstrated on metal oxide electrodes, with stability on the order of hours. The catalytic surfaces can be recycled by controlled release of the guest from the host cavities and readsorption of fresh guest. </p>
Data from: Role of mass transport in electrochemical carbon dioxide reduction to methanol using immobilized cobalt phthalocyanine
<p><strong>Cell files.zip</strong></p><ul><li>.dwg files of the pocket for the cathode and anode chamber. </li><li>.dwg files of the gasket design</li></ul><p><strong>Experimental data.zip</strong> (>60 experiments)</p><ul><li>Chronoamperometry data</li><li>Each experiment has a mpr and txt file. The .mpr file can be read by EC-lab software, while the txt file has the raw data.</li><li>H-NMR data</li><li>Each experiment has its own folder, then another folder with the experiment number. Within that experiment number folder is .fid file needed to view the H-NMR data. </li><li>Gas Chromatography data </li><li>Each experiment has its own folder. the files can be opened using SRI proprietary software. There are also .log files which contain the results of each experiment as the raw data. </li></ul>
Raw data for: Spidroin N-terminal domain forms amyloid-like fibril based hydrogels and provides a protein immobilization platform
<p>Raw data for the article "Spidroin N-terminal domain forms amyloid-like fibril based hydrogels and provides a protein immobilization platform." to be published in Nature communications.</p>
STEM images used for a paper Aberration-Corrected STEM to Determine the Surface Coverage and Distribution of Immobilized Molecular Complexes
<p>Theses are STEM images used to calculate the surface coverage and/or Ripley's K function presented in the paper "Statistical Analysis of HAADF-STEM Images to Determine the Surface Coverage and Distribution of Immobilized Molecular Complexes"</p>
Arsenic immobilization and greenhouse gas emission depend on quantity and frequency of nitrogen fertilization in paddy soil
<p><span>Nitrogen (N) fertilization in paddy soils decreases arsenic mobility and methane emissions. However, it is unknown how quantity and frequency of N fertilization affects the interlinked redox reactions of iron(II)-driven denitrification, iron mineral (trans-)formation with subsequent arsenic (im-)mobilization, methane and nitrous oxide emissions, and how this links to microbiome composition. Thus, we incubated paddy soil from Vercelli, Italy, over 129 days and applied nitrate fertilizer at different concentrations (control: 0, low: ~35, medium: ~100, high: ~200 mg N kg<sup>-1 </sup>soil<sup>-1</sup>) once at the beginning and after 49 days. In the high N treatment, nitrate reduction was coupled to oxidation of dissolved and solid-phase iron(II), while naturally occurring arsenic was retained on iron minerals due to suppression of reductive iron(III) mineral dissolution. In the low N treatment, 40 µg L<sup>-1</sup> of arsenic was mobilized into solution after nitrate depletion, with 69% being immobilized after a second nitrate application. In the non-fertilized control, concentrations of dissolved arsenic were as high as 76 µg L<sup>-1</sup>, driven by mobilization of 36% of the initial mineral-bound arsenic. Generally, N fertilization led to 1.5-fold higher total GHG emissions (sum of CO<sub>2</sub>, CH<sub>4</sub> and N<sub>2</sub>O as CO<sub>2</sub> equivalents), 158-fold higher </span><span>N<sub>2</sub>O</span><span>, and 7.5-fold lower CH<sub>4</sub> emissions compared to non-fertilization. On day 37, <em>Gallionellaceae</em>, <em>Comamonadaceae</em> and <em>Rhodospirillales</em> were more abundant in the high N treatment compared to the non-fertilized control, indicating their potential role as key players in nitrate reduction coupled to iron(II) oxidation. The findings underscore the dual effect of N fertilization, immobilizing arsenic in the short-term (low/medium N) or long-term (high N), while simultaneously increasing N<sub>2</sub>O and lowering CH<sub>4</sub> emissions. This highlights the significance of both the quantity and frequency of N fertilizer application in paddy soils. </span></p>
Fig. 1 in Reflex Bleeding in Tonically Immobilized Larvae Causes Debris-Based Camouflage in the Blue Death-Feigning Beetle, Asbolus verrucosus LeConte (Coleoptera: Tenebrionidae)
Fig. 1. Selected developmental measurements of Asbolus verrucosus. A) Histogram of the number of eggs hatching at ambient temperature based on number of days after collection (n = 199), B) Head capsule widths for larvae, C) Time to pupation (circles, n = 12) or eclosion (diamonds, n = 11) for mature larvae transferred to 88 °F at different ages, D) Time required to induce pupation (circles, n = 12) or eclosion (diamonds, n = 11) after mature larvae were transferred to 88 °F at different ages.
Fig. 3 in Reflex Bleeding in Tonically Immobilized Larvae Causes Debris-Based Camouflage in the Blue Death-Feigning Beetle, Asbolus verrucosus LeConte (Coleoptera: Tenebrionidae)
Fig. 3. Death feigning in Asbolus verrucosus. A) Adult beetle feigning death, B) Survival analysis of adult death feigning (n = 24), C) Larva feigning death, D) Survival analysis of larval death feigning (n = 32). Scale bars: 1 cm.
Fig. 2 in Reflex Bleeding in Tonically Immobilized Larvae Causes Debris-Based Camouflage in the Blue Death-Feigning Beetle, Asbolus verrucosus LeConte (Coleoptera: Tenebrionidae)
Fig. 2. Captive-bred Asbolus verrucosus pupae and adults. A) Ventral view of a pupa, B) Lateral view of a pupa, C) Dorsal view of a newly eclosed adult, D) Rugose elytra inside elytral sheath from a preserved specimen, E) Tergite with setae from a preserved specimen, F) Setae near urogomphi, G–I) Teneral adults at increasing ages. Scales for top and bottom rows are 5 mm and 0.5 mm for the middle row.
Fig. 4 in Reflex Bleeding in Tonically Immobilized Larvae Causes Debris-Based Camouflage in the Blue Death-Feigning Beetle, Asbolus verrucosus LeConte (Coleoptera: Tenebrionidae)
Fig. 4. Reflex bleeding in Asbolus verrucosus. A) Two recently exhumed larvae feigning death. The larva on the top (arrow) bled and was obscured by debris, B) Exudate (arrows) originating from regions proximal to the second abdominal sternite, C) Micrograph of the exudate (differential interference contrast image merged with DAPI stained image) revealed hemocytes were present, D) Abdominal pleuron near second sternite in a larva prior to reflex bleeding (arrow indicates site where larva bled), E) Same larva as in (D), showing melanization at the site about 10 minutes after bleeding. Scales in A and B are 1 cm, C is 5 mm, D and E are 0.1 cm.
One-Step Photochemical Immobilization of Aptamer on Graphene for Label-Free Detection of NT-proBNP
<p>A novel photochemical technological route for one-step functionalization of a graphene surface with an azide-modified DNA aptamer for biomarkers is developed. The methodology is demonstrated for the functionalization of a DNA aptamer for an N-terminal B-type natriuretic peptide (NT-proBNP) heart failure biomarker on the surface of a graphene channel within a system based on a liquid-gated graphene field effect transistor (GFET). The limit of detection (LOD) of the aptamer-functionalized sensor is 0.01 pg/mL with short response time (75 s) for clinically relevant concentrations of the cardiac biomarker, which could be of relevance for point-of-care (POC) applications. The novel methodology could be applicable for the development of different graphene-based biosensors for fast, stable, real-time, and highly sensitive detection of disease markers.</p>
The Efficacy of Different Immobilization Times After Achilles Tendon Rupture Surgery
ClinicalTrials.gov study NCT04663542. IPD Sharing: NO. Countries: 1. Publications: 2.
Duration of Immobilization After Rotator Cuff Repair: Its Clinical Impact
ClinicalTrials.gov study NCT00891566. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Immobilization Without Reduction vs. Reduction Under General Anesthesia in Metaphyseal Fractures of the Distal Radius
ClinicalTrials.gov study NCT05008029. IPD Sharing: YES. Countries: 1. Publications: 2.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.