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109
datasets available to search
ShareScore release 0.9.0
Dataset results
109 results for “in vivo imaging”
Animal histological images for <em>in vivo</em> maximum tolerated dose and toxicity
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In vivo timelapse imaging and analysis of Golgi satellite organelle distribution and movement in the neural progenitor cells of the brain
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In vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169 in multiple routes of transmission
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Wide-field fluorescence lifetime imaging of neuron spiking and sub-threshold activity in vivo
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Data from: Three-photon in vivo imaging of neurons and glia in the medial prefrontal cortex with sub-cellular resolution
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In Vivo Near-Infrared Imaging Using Ternary Selenide Semiconductor Nanoparticles with an Uncommon Crystal Structure
<p>Dataset of </p> <table> <tbody> <tr> <td>https://zenodo.org/record/5793282#.YcCG4GjMJPY</td> </tr> </tbody> </table>
In vivo probabilistic atlas of white matter tracts of the human subthalamic area combining track density imaging and optimized diffusion tractography
<p>Sample code to reproduce the results of the paper "In vivo probabilistic atlas of white matter tracts of the human subthalamic area combining track density imaging and optimized diffusion tractography", by Basile et al., Brain Structure and Function 2022. </p> <p>The repository also includes the probabilistic atlas of the human subthalamic area.</p>
dataset for root canal configuration of mandibular first and second premolars using in vivo cone-beam computed tomography imaging
<p>dataset for root canal configuration of mandibular first and second premolars using in vivo cone-beam computed tomography imaging</p>
Fig. 2. A in Microstructural Impact of Ischemia and Bone Marrow-Derived Cell Therapy Revealed With Diffusion Tensor Magnetic Resonance Imaging Tractography of the Heart In Vivo
Fig. 2. A picture of four male - female pairs of Amblyomma variegatum attached on a cow examined during this survey. © Anne Laudisoit.
Fig. 1 in Microstructural Impact of Ischemia and Bone Marrow-Derived Cell Therapy Revealed With Diffusion Tensor Magnetic Resonance Imaging Tractography of the Heart In Vivo
Fig. 1. Map of Kisangani and Major transhumance routes from probable departure location to Kisangani city, DR Congo.
Example dataset for in vivo blood sO2 imaging with ultrasound-aided large-scale optoacoustic microscopy
<p>"mouse1_r_5um_dualwave.mat" and "mouse1_r_10um_us.mat" contain the raw datasets in dual-wavelength optoacoustic and ultrasound modes acquired with ultrasound-aided large-scale optoacoustic microscopy on mouse dorsal skin.</p> <p>"mouse1_r.mat" contains the estimated skin surface based on the ultrasound dataset.</p> <p>After downloading the above 3 files, make a subfolder under the current working folder and name it "skinCropDepths", and put "mouse1_r.mat" under that subfolder.</p> <p>The code can be fetched from this Github repository: https://github.com/razanskylab/dualwaveProcessor. Refer to README file for explanation on the code base.</p> <p>The datasets shared here were acquired on healthy mouse dorsal skin and are intended for testing the unmixing scripts.</p> <p>The longitudinal datasets acquired during dorsal skin wound healing are too large to be publically shared, but is available for research purposes upon reasonable request: weiye.li@uzh.ch.</p> <p> </p> <p> </p>
In Vivo Rodent Cervicothoracic Vasculature Imaging Using Photoacoustic Computed Tomography
<p>These video clips are the supplementary video for the manuscript "<em>In Vivo</em> Rodent Cervicothoracic Vasculature Imaging Using Photoacoustic Computed Tomography" submitted to <em>Photonics</em>.</p>
Label-free imaging of M1 and M2 macrophage phenotypes in the human dermis in vivo using two-photon excited FLIM
<p>Macrophages (ΜΦs) are important immune effector cells that promote (M1 ΜΦs) or inhibit (M2 ΜΦs) inflammation and are involved in numerous physiological and pathogenic immune responses. Their precise role and relevance, however, are not fully understood for lack of non-invasive quantification methods. Here, we show that two-photon excited fluorescence lifetime imaging (TPE-FLIM), a label-free non-invasive method, can visualize ΜΦs in the human dermis in vivo. We demonstrate in vitro that human dermal ΜΦs exhibit specific TPE-FLIM properties that distinguish them from the main components of the extracellular matrix and other dermal cells. We visualized ΜΦs, their phenotypes and phagocytosis in the skin of healthy individuals in vivo using TPE-FLIM. Additionally, machine learning identified M1 and M2 MФs with a sensitivity of 0.88±0.04 and 0.82±0.03 and a specificity of 0.89±0.03 and 0.90±0.03, respectively. In clinical research, TPE-FLIM can advance the understanding of the role of MФs in health and disease.</p>
Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors
<p>Elucidating how synaptic molecules such as AMPA receptors mediate neuronal communication and tracking their dynamic expression during behavior is crucial to understand cognition and disease, but current technological barriers preclude large-scale exploration of molecular dynamics in vivo. We have developed a suite of innovative methodologies that break through these barriers: a new knockin mouse line with fluorescently tagged endogenous AMPA receptors, two-photon imaging of hundreds of thousands of labeled synapses in behaving mice, and computer vision-based automatic synapse detection. Using these tools, we can longitudinally track how the strength of populations of synapses changes during behavior. We used this approach to generate an unprecedentedly detailed spatiotemporal map of synapses undergoing changes in strength following sensory experience. More generally, these tools can be used as an optical probe capable of measuring functional synapse strength across entire brain areas during any behavioral paradigm, describing complex system-wide changes with molecular precision.</p>
Supplementary data for "Engineering PD-1-targeted small protein variants for in vitro diagnostics and in vivo PET imaging"
<p>Supplementary data for "Engineering PD-1-targeted small protein variants for in vitro diagnostics and in vivo PET imaging". The docking.zip file contains ClusPro protein/protein docking results for all binding protein variants using either murine PD-1 structure (3bikB) or human PD-1 AF2 model as receptors. The pymol session contains data and scenes used to generate the Figures in the paper.</p>
Ex-vivo Confocal Imaging and Proteomic Profiling to Determine Treatment Response in Children With IBD
ClinicalTrials.gov study NCT07121920. IPD Sharing: NO. Countries: 1. Publications: 14.
In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer
ClinicalTrials.gov study NCT03943966. IPD Sharing: UNDECIDED. Countries: 1. Publications: 26.
LightPathTM Imaging System for Ex-vivo Assessment of Margin and Lymph Node Status in Breast Cancer Surgical Specimens
ClinicalTrials.gov study NCT02037269. IPD Sharing: NO. Countries: 1. Publications: 1.
Quantitative GLP-1 Receptor Imaging Correlated to ex Vivo Distribution of In-111-exendin
ClinicalTrials.gov study NCT03889496. IPD Sharing: NO. Countries: 1. Publications: 1.
In Vivo Imaging of Pigmentary Disorders by Reflectance Confocal Microscopy
ClinicalTrials.gov study NCT00771355. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.