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ShareScore release 0.9.0
Dataset results
62 results for “interconnect”
A Bilateral Interconnected DIEP Flap Based on One Vessel Pedicle for Breast Reconstruction
ClinicalTrials.gov study NCT00514748. IPD Sharing: Not stated. Countries: 1. Publications: 11.
Comprehensive Assessment of Interconnection Between Brain Emotional Activity and Coronary Plaque Instability
ClinicalTrials.gov study NCT04853511. IPD Sharing: NO. Countries: 1. Publications: 3.
INTERconNEcT-Eds: a Guided Self-help Mobile App to Improve Outcome in Eating Disorders
ClinicalTrials.gov study NCT06551974. IPD Sharing: YES. Countries: 1. Publications: 1.
Data from: Whole-genome sequences of Malawi cichlids reveal multiple radiations interconnected by gene flow
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Data from: The impact of conservation management on the community composition of multiple organism groups in eutrophic interconnected man-made ponds
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Supplemental material for 'A quest through interconnected datasets: lessons from highly-cited ICASSP papers'
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Data from: Hybrid asexuality as a primary postzygotic barrier between nascent species: on the interconnection between asexuality, hybridization and speciation
Although sexual reproduction is ubiquitous throughout nature, the molecular machinery behind it has been repeatedly disrupted during evolution, leading to the emergence of asexual lineages in all eukaryotic phyla. Despite intensive research, little is known about what causes the switch from sexual reproduction to asexuality. Interspecific hybridization is one of the candidate explanations but the reasons for the apparent association between hybridization and asexuality remain unclear. In this study we combined cross-breeding experiments with population genetic and phylogenomic approaches to reveal the history of speciation and asexuality evolution in European spined loaches (Cobitis). Contemporary species readily hybridize in hybrid zones, but produce infertile males and fertile but clonally reproducing females that cannot mediate introgressions. However, our analysis of exome data indicates that intensive gene flow between species has occurred in the past. Crossings among species with various genetic distances showed that, while distantly related species produced asexual females and sterile males, closely related species produce sexually reproducing hybrids of both sexes. Our results suggest that hybridization leads to sexual hybrids at the initial stages of speciation, but as the species diverge further, the gradual accumulation of reproductive incompatibilities between species could distort their gametogenesis towards asexuality. Interestingly, comparative analysis of published data revealed that hybrid asexuality generally evolves at lower genetic divergences than hybrid sterility or inviability. Given that hybrid asexuality effectively restricts gene flow, it may establish a primary reproductive barrier earlier during diversification than other 'classical' forms of postzygotic incompatibilities. Hybrid asexuality may thus indirectly contribute to the speciation process.
Data from: Hybrid asexuality as a primary postzygotic barrier between nascent species: on the interconnection between asexuality, hybridization and speciation
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RAD51 Interconnects Between DNA Replication DNA Repair and Immunity
RAD51 a multifunctional protein plays a central role in DNA replication and homologous recombination repair and is known to be involved in cancer development. We identified a novel role for RAD51 in innate immune response signaling. Defects in RAD51 lead to the accumulation of self-DNA in the cytoplasm triggering a STING-mediated innate immune response after replication stress and DNA damage. Our data suggest that in addition to playing roles in homologous recombination-mediated DNA double-strand break repair and replication fork processing RAD51 is also implicated in the suppression of innate immunity. Thus our study reveals a previously uncharacterized role of RAD51 in initiating immune signaling placing it at the hub of new interconnections between DNA replication DNA repair and immunity. Overall design Gene expression analysis of WT and sh RAD51 HT1080 cells was carried out before and after 1 Gy of high LET Fe particle radiation.
Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia
GEO Series GSE109367. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Transcription factor reveals interconnected regulation of carbon source utilization and carbon catabolite repression in an oleaginous yeast
GEO Series GSE293943. Rhodotorula toruloides. 18 samples. Type: Expression profiling by high throughput sequencing.
Hierarchy and interconnected networks in the WhiB7 mediated transcriptional response of Mycobacterium abscessus to ribosome targeting antibiotics
GEO Series GSE233690. Mycobacteroides abscessus. 16 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Densely interconnected transcriptional circuits control cell states in human hematopoiesis
GEO Series GSE24759. Homo sapiens. 211 samples. Type: Expression profiling by array.
Gain of gene regulatory network interconnectivity at the origin of vertebrates
GEO Series GSE148783. Ptychodera flava; Branchiostoma lanceolatum; Xenopus tropicalis; Danio rerio. 75 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
BRD2 interconnects with BRD3 to facilitate Pol II transcription initiation and elongation to prime promoters for cell differentiation [RNA-seq]
GEO Series GSE160558. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Interconnections between RNA-processing pathways revealed by a sequencing-based genetic screen for pre-mRNA splicing mutants in fission yeast
GEO Series GSE79153. Schizosaccharomyces pombe. 20 samples. Type: Expression profiling by array.
Coordination and interconnectivity in the inferred stress-activated signaling network from yeast
GEO Series GSE60613. Saccharomyces cerevisiae. 92 samples. Type: Expression profiling by array; Genome binding/occupancy profiling by genome tiling array.
Gain of gene regulatory network interconnectivity at the origin of vertebrates [RNA-seq]
GEO Series GSE148782. Branchiostoma lanceolatum; Danio rerio. 33 samples. Type: Expression profiling by high throughput sequencing.
Transcription factor reveals interconnected regulation of carbon source utilization and carbon catabolite repression in an oleaginous yeast
GEO Series GSE313844. Rhodotorula toruloides. 30 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide Analysis of Transcriptional Regulators in Human Blood Stem/Progenitor Cells reveals a densely interconnected network of coding and non-coding genes.
GEO Series GSE45144. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.