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823
datasets available to search
ShareScore release 0.9.0
Dataset results
823 results for “kRas”
Study of JDQ443 in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation
ClinicalTrials.gov study NCT04699188. IPD Sharing: YES. Countries: 16. Publications: 1.
ASPECCT: A Study of Panitumumab Efficacy and Safety Compared to Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer
ClinicalTrials.gov study NCT01001377. IPD Sharing: Not stated. Countries: 29. Publications: 7.
Selumetinib Sulfate in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer With KRAS G12R Mutations
ClinicalTrials.gov study NCT03040986. IPD Sharing: NO. Countries: 1. Publications: 1.
A Study to Assess the Efficacy and Safety of Lenalidomide in Combination With Cetuximab in Pre-treated Patients With KRAS Mutant Colorectal Cancer
ClinicalTrials.gov study NCT01032291. IPD Sharing: Not stated. Countries: 6. Publications: 2.
Randomized Phase II Study of AZD6244 (Mitogen-activated Protein Kinase Inhibitor) MEK-Inhibitor With Erlotinib in KRAS Wild Type Advanced Non-Small Cell Lung Cancer (NSCLC) and a Randomized Phase II S
ClinicalTrials.gov study NCT01229150. IPD Sharing: NO. Countries: 1. Publications: 4.
An Open-label Study of GSK1120212 Compared With Docetaxel in Stage IV KRAS-mutant Non-small Cell Lung Cancer
ClinicalTrials.gov study NCT01362296. IPD Sharing: Not stated. Countries: 8. Publications: 1.
AZD6244 in Combination With Docetaxel Versus Docetaxel Alone in KRAS Mutation Positive NSCLC Patients
ClinicalTrials.gov study NCT00890825. IPD Sharing: Not stated. Countries: 12. Publications: 2.
PEAK: Panitumumab Plus mFOLFOX6 vs. Bevacizumab Plus mFOLFOX6 for First Line Treatment of Metastatic Colorectal Cancer (mCRC) Patients With Wild-Type Kirsten Rat Sarcoma-2 Virus (KRAS) Tumors
ClinicalTrials.gov study NCT00819780. IPD Sharing: Not stated. Countries: 6. Publications: 12.
Panitumumab in Cetuximab Refractory KRAS Wild-Type Colorectal Cancer
ClinicalTrials.gov study NCT00842257. IPD Sharing: NO. Countries: 1. Publications: 1.
Study of Combination Therapy With the MEK Inhibitor, Cobimetinib, Immune Checkpoint Blockade, Atezolizumab, and the AUTOphagy Inhibitor, Hydroxychloroquine in KRAS-mutated Advanced Malignancies
ClinicalTrials.gov study NCT04214418. IPD Sharing: YES. Countries: 1. Publications: 0.
A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors
ClinicalTrials.gov study NCT04853017. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Generation of KRAS knockout pancreatic cancer cell line PANC1
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Data from: STAT3 sustains tumorigenicity following mutant KRAS ablation
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Millions of lung tumors harboring KRAS, BRAF, EGFR, and tumor suppressor alterations from genetically engineered mouse models
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Example of KRAS oncogene mutational regression and HLA haplotype characterization in oligo-metastatic colorectal cancer patient (ID: PAT2)
<p>KRAS oncogene mutational regression from primary tumour to lung metastasis (evaluated through TSO500 panel, Illumina Novaseq 6000 platform) and HLA haplotype characterization (through PCR) in a representative oligo-metastatic colorectal cancer patient (ID: PAT2).</p>
Dataset I related to publication: Beyond KRAS(G12C): biochemical and computational characterization of sotorasib and adagrasib binding specificity and the critical role of H95 and Y96
<p>MD simulation data (sotorasib and adagrasib in complex with NRAS(WT) and KRAS(WT)) related to publication: "Beyond KRAS(G12C): biochemical and computational characterization of sotorasib and adagrasib binding specificity and the critical role of H95 and Y96". </p> <p>ACS Chem. Biol. 2024, XXXX, XXX, XXX-XXX</p> <p>https://pubs.acs.org/doi/10.1021/acschembio.4c00315</p> <ul> <li>The .zip files contain raw Desmond simulation trajectories of KRAS(WT) or NRAS(WT) in complex with adagrasib or sotorasib [5 replicas; each 5 us] <ul> <li>(-out.cms files and trajectories).</li> </ul> </li> </ul> <p>Related datasets: 10.5281/zenodo.10781452</p>
Dataset II related to publication: Beyond KRAS(G12C): biochemical and computational characterization of sotorasib and adagrasib binding specificity and the critical role of H95 and Y96
<p>MD simulation data (KRAS(G12C) and KRAS(G12C/Y96D)) related to publication: "Beyond KRAS(G12C): biochemical and computational characterization of sotorasib and adagrasib binding specificity and the critical role of H95 and Y96". </p> <p>ACS Chem. Biol. 2024, XXXX, XXX, XXX-XXX</p> <p>https://pubs.acs.org/doi/10.1021/acschembio.4c00315</p> <ul> <li>The .zip files contain raw Desmond simulation trajectories of KRAS(G12C) and KRAS(G12C/Y96D) with apo SII-P or in complex with sotorasib [5 replicas; each 4 us] <ul> <li>(-out.cms files and trajectories).</li> </ul> </li> </ul> <p>Related datasets: 10.5281/zenodo.10812233 </p>
Single cell data from Imaging Mass Cytometry of mouse lung tumours treated with KRAS-G12C and immune checkpoint inhibitors (Dataset 3)
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Motif-guided Identification of KRAS-interacting Proteins
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Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer
ClinicalTrials.gov study NCT04146298. IPD Sharing: Not stated. Countries: 1. Publications: 3.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.