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826 results for “low level”
Low-Level Laser Therapy for Plantar Fasciitis
ClinicalTrials.gov study NCT05763381. IPD Sharing: YES. Countries: 1. Publications: 36.
Low-level updraft intensification in response to environmental wind profiles
Open the record for dataset details and reuse information.
The effects of a clinically feasible application of low-level laser therapy on the rate of orthodontic tooth movement: A triple-blinded split-mouth randomized controlled clinical trial.
<p>Dataset for all study's analyses.</p>
Switch to second-line versus continued first-line antiretroviral therapy for patients with low-level HIV-1 viremia: an open-label randomized controlled trial in Lesotho
<p>These are pseudo-anonymised data from the SESOTHO randomised trial: "Switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with viremia below 1000 copies/mL – a multicenter, parallel-group, open-label, randomized clinical study in rural Lesotho". There are two datasets, one containing baseline data (one row per participant) and one containing longitudinal viral load data (one row per participant per visit). The data dictionary explains the data available in each dataset. Between August 2017 and August 2019, 80 eligible and consenting participants were enrolled from eight health facilities in four districts of Lesotho, and followed up for nine months. The protocol was published, DOI: 10.1186/s12879-018-2979-y</p>
Low levels of genetic differentiation with isolation by geography and environment in populations of Drosophila melanogaster from across China
<p>The fruit fly <i>Drosophila</i> <i>melanogaster</i> is a model species in evolutionary studies. However, the population processes of this species in East Asia are poorly studied, even though this area was one of the first regions colonized outside of its native distribution range. Here we examined the population genetic structure of <i>D.</i> <i>melanogaster</i> across China. There were 14 mitochondrial haplotypes with ten unique ones out of 23 known from around the globe. Pairwise F<sub>ST</sub> values estimated from 15 novel microsatellites ranged from 0 to 0.11, with geographically isolated populations showing the highest level of genetic uniqueness. STRUCTURE analysis identified high levels of admixture at both the individual and population levels. Mantel tests indicated a strong association between genetic distance and geographical distance as well as environmental distance. Full RDA analysis showed that independent effects of environmental conditions and geography accounted for 62.10% and 31.58% of the total explained genetic variance, respectively. When geographic variables were constrained in a partial RDA analysis, three environmental variables of bio2 (mean diurnal air temperature range), bio13 (precipitation of the wettest month), and bio15 (precipitation seasonality) were correlated with genetic distance. Our study suggests that a high level of gene flow, geographical isolation, and environmental factors have together shaped the population genetic structure of <i>D.</i> <i>melanogaster</i> after its introduction into China.</p>
Low oxygen levels can help to prevent the detrimental effect of acute warming on mitochondrial efficiency in fish
<p>Aerobic metabolism of aquatic ectotherms is highly sensitive to fluctuating climates. Many mitochondrial traits exhibit phenotypic plasticity in response to acute variations in temperature and oxygen availability. These responses are critical for understanding the effects of environmental variations on aquatic ectotherms performance. Using the European seabass, <i>Dicentrarchus labrax</i>, we determined the effects of acute warming and deoxygenation <i>in vitro </i>on mitochondrial respiratory capacities and mitochondrial efficiency to produce ATP (ATP/O ratio). We show that acute warming reduced ATP/O ratio but deoxygenation marginally raised ATP/O ratio, leading to compensatory effect of low oxygen availability on mitochondrial ATP/O ratio at high temperature. The acute effect of warming and deoxygenation on mitochondrial efficiency might be related to the leak of protons across the mitochondrial inner membrane, as the mitochondrial respiration required to counteract the proton leak increased with warming and decreased with deoxygenation. Our study underlines the importance of integrating the combined effects of temperature and oxygen availability on mitochondrial metabolism. Predictions on decline in performance of aquatic ectotherms due to climate change may not be accurate, since these predictions typically look at respiratory capacity and ignore efficiency of ATP production.</p>
A dataset for high-level activity recognition based on low level audio events
<p>The high level activities are:<br> - kitchencleanup<br> - music<br> - no activity<br> - other activity<br> - talk<br> - tv</p> <p>Each recording of low-level audio events is stored in a separate file.</p> <p>Files are organized in 6 folders, each folder corresponding to a separate file.</p> <p>The format of is file is json-like. In particular, each row has the following format:</p> <p>{"prob": 0.88557562121157585, "energy": 0.024511212402412885, "t": 1485110417, "event": "speech"}</p> <p>This dataset can be evaluated with the python code metaClassifier/evaluate.py of the AUOR repository:<br> https://github.com/tyiannak/AUROS</p>
Dataset for Antimicrobial resistance of Neisseria gonorrhoeae in Germany: low levels of cephalosporin resistance but rising azithromycin resistance
<p>This is Dataset used for Publication "Antimicrobial resistance of <em>Neisseria gonorrhoeae</em> in Germany: low levels of cephalosporin resistance but rising azithromycin resistance" and contains data on Information on performed Neisseria gonorrhoeae AMR tests in sentinel Laboratories as well as AMR testing in consiliary Laboratory.</p>
Sustained liver HBsAg loss and clonal T and B cell expansion upon therapeutic DNA vaccination require low HBsAg levels
<p>C57BL/6 mice samples transduced with AAV-HBV, followed by treatment with siRNA+TxTv, control siRNA+TxVx or control siRNA+empty plasmid. 10x genomics (VDJ) was performed in liver IHIC.</p><p>An rds object with the raw and normalised counts, the annotations is available.</p>
Towards geomorphometry of plains - country level unsupervised classification of low-relief areas (Poland)
<p>Catalog "input_rasters" contains ten downsampled geomorphometric variables with 500 m resolution.</p> <p>There are serialized models in .rds format including Gaussian mixture model (<em>GMM_model.rds</em>) and data transformator (<em>transformator.rds</em>) in "models" catalog. The mclust package is required to load the GMM model, and the recipes package is required for the transformator.</p> <p>The map with geomorphological units is saved in the <em>geomorphometry_map.tif</em> file. The map with the calculated uncertainty of these units is saved in the <em>uncertainty_map.tif</em> file. In addition, a separate .xml file with class names is included.</p> <p>All rasters are in the ETRS89 / Poland CS92 (EPSG:2180) coordinate system and GeoTIFF format.</p> <p>The code to reproduce the results can be found in the GitHub repository: <a href="https://github.com/kadyb/geomorph_clustering">https://github.com/kadyb/geomorph_clustering</a></p>
Data from: Even low light pollution levels affect the spatial distribution and timing of activity of a "light tolerant" bat species
<p>Abstract of the related publication :</p> <p>By disrupting nocturnal landscapes worldwide, light pollution caused by Artificial Light At Night (ALAN) is recognised as a major threat to biodiversity. As even low light intensities might affect some taxa, concerns are arising about biological responses to widespread low light levels. We used data from a French citizen science bat monitoring program (1,894 full-nights monitored on 1,055 sites) to explore the landscape-scale effects of light on an open-space-foraging bat species, the Serotine bat (<em>Eptesicus serotinus</em>). We assessed this species' abundance and timing of night-time activity (median time of activity) at foraging sites. ALAN, and to a lesser extent moonlight, reduced <em>E. serotinus</em> abundance. ALAN delayed activity, and this delay was amplified during overcast nights. On the contrary, where there was no ALAN, the higher the cloud cover, the earlier the activity occurred. Cloud cover likely darkened the night sky in rural locations, whereas it amplified skyglow in light-polluted places, increasing ALAN effects on bats. Interestingly, moonlight also delayed activity but this effect was weakened where there was ALAN. Our study shows that even fine variations of light levels could affect the spatiotemporal distribution of a common species usually considered to be “light tolerant”, with potential cascading effects on individual fitness and population dynamics. It stresses how urgent it is to preserve and restore dark areas to protect biodiversity from light pollution while working on light intensity and directivity where ALAN is needed.</p>
Low levels of hybridization between domestic and wild Mallards wintering in the Lower Mississippi Flyway
<p>Mallard ducks are a ubiquitous and socio-economically important game bird in North America. Despite their generally abundant midcontinent population, Mallards in eastern North America are declining, which may be partially explained by extensive hybridization with human-released domestically-derived game-farm Mallards. We investigated the genetic composition of Mallards in the middle and lower Mississippi flyway, key wintering regions for the species. We found that nearly 30% of wild Mallards carried mitochondrial haplotypes derived from domestic mallards present in North America, indicating that the individuals had female game-farm Mallard lineage in their past; however nuclear results identified only 4% of the same sample set as putative hybrids. Recovering 30% of samples with OW A mtDNA haplotypes is concordant with general trends across the Mississippi flyway and this percentage was stable across Mallards we sampled a decade apart. The capture and perpetuation of OW A mtDNA haplotypes is likely due to female breeding structure, whereas reversal of the nuclear signal back to wild ancestry is due to sequential backcrossing and lower and/or declining admixture with game-farm Mallards. Future studies of wild ancestry of Mississippi flyway Mallards will benefit from coupling molecular and spatial technology across flyways, seasons, and years to search for potential transitions of Mallard populations with different genetic ancestry, and whether the genetic ancestry is somehow linked to an individual's natal and subsequent breeding location.</p>
Data from: Low levels of outdoor recreation alter wildlife behavior
<p>Public interest in nature-based recreation is growing, including visitation to protected areas. However, the level of recreation in these areas that causes detectable changes in wildlife behavior remains unknown, and many studies that investigate wildlife responses to humans do so in high-visitation areas. </p> <p>We used camera traps to investigate the spatial and temporal responses of brown bears (<em>Ursus arctos</em>), black bears (<em>Ursus americanus</em>), moose (<em>Alces alces</em>), and wolves (<em>Canis lupis</em>) to experimentally manipulated levels of human activity in Glacier Bay National Park, Alaska during summers 2017 and 2018. Human activity was restricted at some sites and concentrated at others, and these human impact treatments were swapped mid-season. The park has very low on-land visitation (~40,000 on-land tourists per year), making it a unique study system to investigate wildlife responses to low levels of human activity. </p> <p>Detections did not exceed five per week for any species unless human activity was absent (zero photos of humans were taken). However, spatial and temporal patterns of wildlife activity in relation to human activity were nuanced and species-specific. Moose shifted their activity patterns to better align with when people were most active. Black bears were more likely to be detected in areas of high human activity but used high-use areas less intensely than low-use areas. Wolves used areas of high human impact more intensely, but shifted their activity to be more strongly nocturnal. </p> <p>Our results highlight the importance of considering both spatial and temporal responses of wildlife to human activity. Additionally, and arguably most importantly, we detected changes in wildlife behavior in response to humans in a national park with relatively low tourism. Although natural processes may dominate in protected areas, our results indicate that even low levels of human activity can alter wildlife behavior. </p> <p>Synthesis and applications: We demonstrated that nearly any level of human activity in a protected area may alter wildlife behavior. However, it is unreasonable to expect protected areas to be completely devoid of human activity. Thus, management of these areas will need to balance the desires of humans to view wildlife with the likely impacts. </p>
VPS: Excavating High-Level C++ Constructs from Low-Level Binaries to Protect Dynamic Dispatching - (Evaluation Data)
<p>Evaluation data of the published paper: "VPS: Excavating High-Level C++ Constructs from Low-Level Binaries to Protect Dynamic Dispatching". The paper was published at the Annual Computer Security Applications Conference (ACSAC) 2019.</p> <p>The paper is available at: https://www.syssec.ruhr-uni-bochum.de/research/publications/VPS/</p> <p> </p> <p>Ab­stract</p> <p>Po­ly­mor­phism and in­heri­t­an­ce make C++ sui­ta­ble for wri­ting com­plex soft­ware, but si­gni­fi­cant­ly in­crea­se the at­tack sur­face be­cau­se the im­ple­men­ta­ti­on re­li­es on vir­tu­al func­tion ta­bles (vta­bles). These vta­bles con­tain func­tion poin­ters that at­ta­ckers can po­ten­ti­al­ly hi­jack and in prac­tice, vta­ble hi­ja­cking is one of the most im­portant at­tack vec­tor for C++ bi­na­ries. In this paper, we pre­sent VTa­ble Poin­ter Se­pa­ra­ti­on (VPS), a prac­tical bi­na­ry-le­vel de­fen­se against vta­ble hi­ja­cking in C++ ap­p­li­ca­ti­ons. Un­li­ke pre­vious bi­na­ry-le­vel de­fen­ses, which rely on un­sound sta­tic ana­ly­ses to match clas­ses to vir­tu­al call­si­tes, VPS achie­ves a more ac­cu­ra­te pro­tec­tion by re­stric­ting vir­tu­al call­si­tes to va­lidly crea­ted ob­jects. More spe­ci­fi­cal­ly, VPS en­su­res that vir­tu­al call­si­tes can only use ob­jects crea­ted at valid ob­ject con­struc­tion sites, and only if those ob­jects can reach the call­si­te. Mo­re­over, VPS ex­pli­cit­ly prevents false po­si­ti­ves (fal­se­ly iden­ti­fied vir­tu­al call­si­tes) from brea­king the bi­na­ry, an issue exis­ting work does not hand­le cor­rect­ly or at all. We eva­lua­te the pro­to­ty­pe im­ple­men­ta­ti­on of VPS on a di­ver­se set of com­plex, re­al-world ap­p­li­ca­ti­ons (Mon­goDB, MySQL ser­ver, Node.js, SPEC CPU2017/CPU2006), show­ing that our ap­proach pro­tects on aver­a­ge 97.8% of all vir­tu­al call­si­tes in SPEC CPU2006 and 97.4% in SPEC CPU2017 (all C++ bench­marks), with a mo­de­ra­te per­for­mance over­head of 11% and 9% geo­me­an, re­spec­tive­ly. Fur­ther­mo­re, our eva­lua­ti­on re­veals 86 false ne­ga­ti­ves in VTV, a po­pu­lar sour­ce-ba­sed de­fen­se which is part of GCC.</p>
Primary-level worker interventions for the care of mental disorders and distress in low- and middle-income countries - GRADE evidence profiles
<p>This file includes all GRADE evidence profiles for the following Cochrane review:</p> <p>van Ginneken N, Chin WY, Lim YC, Ussif A, Singh R, Shahmalak U, Purgato M, Rojas-García A, Uphoff E, McMullen S, Foss HS, Thapa Pachya A, Rashidian L, Borghesani A, Henschke N, Chong L-Y, Lewin S. Primary-level worker interventions for the care of mental disorders and distress in low- and middle-income countries. Cochrane Database of Systematic Reviews. In press</p>
CESM data: Response of the low-level jet to precession and itsimplications for proxies of the Indian monsoon
<p>This repository contains the simulation output of precession minimum and maximum experiments carried out using the CESM 1.2.0. The experimental setup is the same as that of Bosmans et al. (2014). Each simulation is run of 100 years, and the Jun-Jul-Aug mean of the last 50 years of the simulation is provided here. The climatological monthly mean of total precipitation from the pre-industrial control simulation is also deposited here. </p> <p> </p> <p>Contact: Chetankumar Jalihal<br> email: jalihal@iisc.ac.in</p> <p> </p> <p>Acknowledgments:<br> These simulations were carried out as a part of Chetankumar Jalihal's Ph.D. thesis, funded by the Ministry of Human Resource Development, Government of India, and the Centre for Excellence in the Divecha Centre for Climate Change (DCCC), supported by the Department of Science and Technology, Government of India. We also acknowledge the Supercomputer Education and Research Centre (SERC), Indian Institute of Science, Bangalore, for making available the computation facilities to carry out the simulations.</p>
Genetic assessment reveals inbreeding, possible hybridization, and low levels of genetic structure in a declining goose population
<p>The population numbers of taiga bean goose (<i>Anser fabalis fabalis</i>) have halved during recent decades. Since this subspecies is hunted throughout most of its range, the decline is of management concern. Knowledge of the genetic population structure and diversity is important for guiding management and conservation efforts. Genetically unique subpopulations might be hunted to extinction if not managed separately, and any inbreeding depression or lack of genetic diversity may affect the ability to adapt to changing environments and increase extinction risk. We used microsatellite and mitochondrial DNA markers to study the genetic population structure and diversity among taiga bean geese breeding within the Central flyway management unit using non-invasively collected feathers. We found some genetic structuring with the maternally inherited mitochondrial DNA between four geographic regions (<i>ɸ</i><sub>ST</sub> = 0.11-0.20) but none with the nuclear microsatellite markers (all pairwise <i>F</i><sub>ST</sub>-values 0.002- 0.005). These results could be explained by female natal philopatry and male-biased dispersal, which completely homogenizes the nuclear genome. Therefore, the population could be managed as a single unit. Genetic diversity was still at a moderate level (average <i>H</i><sub>E</sub> = 0.69) and there were no signs of past population size reductions, although significantly positive inbreeding coefficients in all sampling sites (<i>F</i><sub>IS</sub> = 0.05-0.10) and high relatedness values (<i>r </i>= 0.60-0.86) between some individuals could indicate inbreeding. In addition, there was evidence of either incomplete lineage sorting or introgression from the pink-footed goose (<i>A. brachyrhynchus</i>). The current population is not under threat by genetic impoverishment but monitoring in the future is desirable.</p>
Radiative transfer model and datasets for Li et al. (2023), 'Wintertime low-level clouds over sea ice cool the Arctic climate system'
<p>Source code for the radiative transfer model (RAPRAD) and cloud radiative flux data used in the study Li et al. (2022).</p>
Low-level Laser Therapy and Static Stretching in Knee Osteoarthritis.
ClinicalTrials.gov study NCT01738737. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Low Plasma Mannose Binding Lectin (p-MBL) Level is a Risk Factor for Recurrent Pregnancy Loss (RPL)
ClinicalTrials.gov study NCT04017754. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.