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4,566 results for “marker”
Data inputs and results from AI-supported title and abstract screening "Lack of evidence regarding markers identifying acute heart failure in patients with COPD: an AI-supported systematic review"
<p>These comma-separated data files were used to conduct the AI supported screening of [Lack of Evidence Regarding Markers Identifying Acute Heart Failure in Patients with COPD: An AI-supported Systematic Review (working title)], following the methodology described in the publication (URL/doi to be uploaded).</p> <p>These files provide insight into the AI-supported screening process and the choices made by the human reviewer.</p>
Summary of PCR based markers used in this study
<p>Markers corresponding to the <em>atv</em>, <em>An2-like</em>, <em>Ant1</em>, <em>B</em>, and <em>u </em>loci for candidate gene development and QTL validation. Marker type and the restriction enzyme used are provided.</p>
LA1141 × OH8245 inbred backcross (IBC) single nucleotide polymorphism (SNP) markers for genetic studies
<p>The LA1141 × OH8245 157 polymorphic SNP markers from an optimized tomato panel Sim et al., 2012 were used for linkage map construction in the BC<sub>2</sub>S<sub>3</sub> IBC and composite interval mapping QTL analysis. Genetic map position and physical position corresponding to Sl4.0 (Hosmani et al., 2019), and flanking sequences are provided.</p>
Context-Aware Activity Recognition in Logistics (CAARL) – A optical marker-based Motion Capture Dataset
<p><strong>CAARL </strong>is a freely accessible logistics-dataset for human activity recognition, which contains human movement and context information from two subjects. The context information includes the positions of objects such as two picking carts, a packaging table, different racks, a base and three entrances.</p> <p>In the ’Innovationlab Hybrid Services in Logistics’ at TU Dortmund University, two picking and one packing scenarios were recorded using an optical marker based motion capture system. Each subject and object is equipped with several markers. 140 minutes of human movements have been labelled and categorised into 8 activity classes and 19 binary coarse-semantic descriptions, also called attributes. The labelled human movements are synchronised with the context information. They have exactly the same sampling rate (same start and end).</p> <p>The oMoCap data is in csv format. Further formats (e.g. C3D) are available on request.</p> <p>CAARL is based on the set-up and scenarios of the LARa dataset, which contains only human movements. Information about LARa can be found in the dataset and the associated paper:</p> <ul> <li>Dataset: “Logistic Activity Recognition Challenge (LARa) – A Motion Capture and Inertial Measurement Dataset”, Zenodo 2020, DOI: <a href="https://doi.org/10.5281/zenodo.3862782">10.5281/zenodo.3862782</a></li> <li>Paper: “LARa: Creating a Dataset for Human Activity Recognition in Logistics Using Semantic Attributes”, Sensors 2020, DOI: <a href="https://doi.org/10.3390/s20154083">10.3390/s20154083</a></li> </ul> <p> </p> <p><strong>If you use the CAARL dataset for research, please cite the following paper: “Context-Aware Human Activity Recognition in Industrial Processes”, Sensors 2021, DOI: <a href="https://doi.org/10.3390/s22010134">10.3390/s22010134</a></strong></p>
Assessment of skin autofluorescence and its association with glycated hemoglobin, cardiovascular risk markers and concomitant chronic diseases in children with type 1 diabetes
<p>This is the dataset for the publication "Assessment of skin autofluorescence and its association with glycated hemoglobin, cardiovascular risk markers and concomitant chronic diseases in children with type 1 diabetes".</p>
Data archive for Pepper, Bateson and Nettle, 'Telomeres as integrative markers of exposure to stress and adversity: A systematic review and meta-analysis'
<p>Data archive for the paper 'Telomeres as integrative markers of exposure to stress and adversity: A systematic review and meta-analysis' by Gillian Pepper, Melissa Bateson and Daniel Nettle. This version was uploaded in July 2018 after peer-review in the journal Royal Society Open Science. Compared to earlier version, it incorporates some minor error correction to the dataset, and reflects the revised analyses we performed after peer review. </p> <p>Our protocol and recording guide, which were preregistered on the Open Science Framework in 2016, are also included here, as is our PRISMA diagram.</p> <p>The data file 'unprocessed data' contains the data as extracted from the literature, with associations shown both as provided in the original papers, and converted to correlation coefficients. The algorithms for converting all the different associations to correlation coefficients are described in the flowchart and implemented in the R script 'effect conversion algorithms.r'.</p> <p>The data file 'processed data.csv' is the dataset analysed in the paper. Compared to 'unprocessed data.csv', it excludes: associations from studies of non-human animals; duplicate associations; a small number of associations from studies of medical treatments; and associations considered subparts or subscales of other associations. These exclusions are outlined in Methods section of the paper. In addition, in the processed data file, all correlations are aligned in direction so as to make them comparable (variable 'ValencedEffect'); and all associations are assigned to broad and fine categories.The script 'unprocessed to processed.r' makes the processed data file from the unprocessed one, or you can simply work from the processed one directly. </p> <p>The R script 'telomere metanalysis script RSOS REVISED.r' reproduces the analyses found in the paper.</p> <p>This version of the archive (July 17 2018) contains one small correction in the data files compared to all earlier versions. </p>
Dataset related to article "New in silico models to predict in vitro micronucleus induction as marker of genotoxicity"
<p>The .txt file contains the dataset of the in silico model for genotoxicity as induction of micronuclei.</p> <p>The .doc file contains the descriptors of the models and the structural alerts.</p>
TF-Marker: A comprehensive manually curated database for transcription factors and related markers in specific cell and tissue types in human.
<p>Here, we developed the TF-Marker database (TF-Marker, http://bio.liclab.net/TF-Marker/) which is committed to a comprehensive manual curation of TFs and related markers with experimental evidence in specific cell and tissue types in human. Currently, through reviewing <strong>2,091</strong> published literature, we have manually classified TFs and related markers into five types according to their functions: 1) <strong>TF</strong>: TFs, which regulate the expression of markers; 2) <strong>T Marker</strong>: markers, which are regulated by TFs (TF and T Marker pairs can identify cell types more specifically); 3) <strong>I Marker</strong>: markers, which influence the activity of TFs (I Markers can also influence the development of specific cells and tissues); 4) <strong>TFMarker</strong>: TFs, which play roles as markers (TFMarkers are cell/tissue-specific TFs used as cell markers in biology experiments); and 5) <strong>TF Pmarker</strong>: TFs, which play roles as potential markers. By curating thousands of published literature, <strong>5,905</strong> entries including <strong>1,316</strong> TFs, <strong>1,092</strong> T Markers, <strong>473</strong> I Markers, <strong>1,600</strong> TFMarkers and <strong>1,424</strong> TF Pmarkers, were annotated in <strong>383</strong> cell types and <strong>95</strong> tissue types in human. Moreover, TF-Marker divided markers into disease markers and tissue/cell-specific markers. TF-Marker is an elaborate database, which provides TFs and related markers supported by experimental evidence. We believe TF-Marker will provide strong support for research into cell/tissue-specific TFs and related markers.</p>
Deconvolved STED nanoscopy images of the nuclear phosphatidylinositol 4,5-bisphosphate and nuclear speckle marker SON together with deconvolved confocal images of DAPI stained nuclei in human formalin-fixed paraffin-embedded skin warts sections
<p>The collection and analysis of formalin-fixed paraffin-embedded (FFPE) human skin sections was approved by the local ethics-committee at the Department of Pathology, University of Cologne, Germany. Written informed consentwas obtained from all patients in accordance with the Declaration of Helsinki. For biopsy materials from archival paraffin blocks of human skin, an informed consent was obtained from all the subjects and ethical approval obtained from the Ethics Committee at the University of Cologne. Surgically removed human FFPE skin biopsies were sectioned into 4 µm sections. Sections were dewaxed, and indirectly immunofluorescently labeled against nuclear phosphatidylinositol 4,5-bisphosphate (nPI(4,5)P2) using 5 µg/mL rabbit primary polyclonal antibody (Echelon Biosciences Inc. Z-A045, clone 2C11). The primary antibody against nPI(4,5)P2 was recognized by the goat secondary antibody conjugated with Abberrior Star 635P (Abberior 2-0002-007-5). Sections were indirectly immunofluorescently labeled against nuclear speckle marker SON using 1 µg/mL rabbit primary polyclonal antibody (Abcam ab121759). The primary antibody against SON was recognized by the goat secondary antibody conjugated with Abberrior Star 580 (Abberrior ST580-1002). Sections were co-stained by DAPI 1:1000 in PBS for 5 min.</p> <p>Imaging of nPI(4,5)P2-635P channel was performed on Leica TCS SP8 STED 3x inverted DMi8 microscope with pulsed white light laser 470-640 nm 1.5 mW and 775 nm pulse STED laser >1.5 W controlled by Leica Application Suite X software and equipped with HC PL APO CS2 100x/1.40 OIL objective used with Leica Type F immersion oil n=1.518. Unidirectional xyz scanning speed was 400 Hz, line accumulation 8. Pixel size was 20 nm in X and Y. Channel settings: 7% 633 nm laser; 775 Notch filter; 50% 775 nm STED laser; 30% 3D STED; HyD 639-698 nm, photon-counting mode, gain 100, gating 0.3-10 ns. Imaging of SON-580 channel was performed on Leica TCS SP8 STED 3x inverted DMi8 microscope with pulsed white light laser 470-640 nm 1.5 mW and 775 nm pulse STED laser >1.5 W controlled by Leica Application Suite X software and equipped with HC PL APO CS2 100x/1.40 OIL objective used with Leica Type F immersion oil n=1.518. Unidirectional xyz scanning speed was 400 Hz, line accumulation 8. Pixel size was 20 nm in X and Y. Channel settings: 10% 585 nm laser; 775 Notch filter; 80% 775 nm STED laser, 30% 3D STED; Hybrid detector (HyD) 589-616 nm, photon-counting mode, gain 100, gating 0.4-10 ns.</p> <p>Z-stacks of STED images were deconvolved using Huygens Professional 22.10 software (Scientific Imaging B.V.). Data sets were processed using Workflow Processor. The workflow consisted of selecting images, setting up the microscopy and deconvolution parameters and saving deconvolved images as 8-bit TIFF single files for individual channels (which were later used for the quantitative analyses; see below). Microscopy parameters were optimized and set as follows. Sampling intervals were ≤20 nm in X and Y and ≤20 nm in Z. Numerical aperture was 1.4; refractive indexes of the lens immersion oil was 1.518 and of the embedding media 1.458; objective quality was good, coverslip position was 0 µm and imaging direction was downward. For nPI(4,5)P2-635P STED channel the backprojected pinhole was 216 nm; excitation (ex.) and emission (em.) wavelengths (λ) were 633 and 651 nm, resp., ex. fill factor 2. STED depletion mode was pulsed, saturation factor 25, STED λ = 775, STED immunity factor 10 and STED 3X was 30%. Classic MLE algorithm with stabilization of Z-slices was used and signal-to-noise ratio was 5.1. For SON-580 STED channel the backprojected pinhole was 195 nm; excitation (ex.) and emission (em.) wavelengths (λ) were 585 and 602 nm, resp., ex. fill factor 2. STED depletion mode was pulsed, saturation factor 20, STED λ = 775, STED immunity factor 10 and STED 3X was 30%. Classic MLE algorithm with stabilization of Z-slices was used and signal-to-noise ratio was 4.</p>
Three systems of molecular markers reveal genetic differences between varieties sabina and balkanensis in the Juniperus sabina L. range
<p>Genotypes of 94 Juniperus sabina samples from 14 populations at SNP (Jsabina_SNPs.txt) and SilicoDArT (Jsabina_SilicoDArTs.txt) loci investigated using the DArTseq technology developed by Diversity Array Technology Pty Ltd (DArT, Canberra, ACT, Australia)</p>
Marker parameter files for the cfTools R package
<p>This Zenodo repository contains the data for the <em>cfTools</em> R package. It includes the shape parameters of beta distribution characterizing methylation markers associated with four tumor types for the <em>CancerDetector</em> function, as well as the shape parameters of beta distribution characterizing methylation markers specific to 29 primary human tissue types for the <em>cfDeconvolve</em> function.</p>
Genetic diversity, population structure, and linkage disequilibrium among tropical quality protein maize (QPM) lines assessed with high-density SNP markers
<p>The study of genetic diversity (GD), population structure, and linkage disequilibrium (LD) provides a better understanding of the genetic relationships between individuals in a population which can be utilized in crop research and improvement. Genotyping-by-sequencing (GBS) was used to detect and genotype single nucleotide polymorphisms (SNPs) in a collection of 74 quality protein maize (QPM) lines and further to characterize their genetic diversity, population structure, and linkage disequilibrium. A total of 235,214 high-quality SNPs were used for different genetic analyses except for structure analysis where 11,950 SNPs were used. Analysis of molecular variance (AMOVA) based on these SNPs revealed high genetic heterozygosity among the five populations with 1% of the total genetic variation present among the subpopulations and 99% of the variation among individuals within the populations. Population structure analysis using Bayesian-based clustering revealed that the 74 lines could be clustered into four groups. However, neighbor-joining trees indicate the lines are grouped into three major clusters. Further analysis using principal component analyses (PCA) clustered the genotypes into five groups which are concordant with the groups based on pedigree information. Higher genetic diversity was detected in population 1 with a GD value of 0.484 and the lowest in population 5 (0.396) and overall, with a mean of 0.434. The LD pattern in the quality protein maize was investigated and we observed a relatively rapid LD decay of 3.53kb and 10.66kb at r<sup>2</sup> =0.2 and r<sup>2</sup>= 0.1, respectively. Our findings provide important information for future Linkage mapping studies, genome-wide association analyses, and marker-assisted selective breeding of maize as well as genomic prediction-based selection in tropical germplasm.</p>
Kelp Metapopulations: Macrocystis pyrifera microsatellite marker biogeography study
Dataset contains microsatellite genotypes specific for Macrocystis pyrifera (giant kelp). Table 1 describes seven loci from blades collected from 62 sites from Alaska, USA, to Baja California, Mexico, and Table 2 blades collected at 38 sites (subpopulations) in central California (Monterey Bay). Each row is the multilocus genotype for a single specimen (individual). These data were described in <ulink url="http://dx.doi.org/10.1111/mec.13371">Johansson ML, Alberto F, Reed DC, Raimondi PT, Coelho NC, Young MA, Drake PT, Edwards CA, Cavanaugh K, Assis J, Ladah LB, Bell TW, Coyer JA, Siegel DA, Serrão EA (2015) Seascape drivers of Macrocystis pyrifera population genetic structure in the northeast Pacific. Molecular Ecology. 24, 4866–4885.</ulink>
Data and code for "Homeric -phi(n) is an oblique case marker"
<p>This repository contains the data and R code for the paper "Homeric -<em>phi(n)</em> is an oblique case marker," <em>Transactions of the Philological Society</em> 118:343–375, 2020. doi: <a href="https://doi.org/10.1111/1467-968X.12192">10.1111/1467-968X.12192</a>. </p>
GenBank accession numbers of the four marker genes and associated voucher specimens/tissues that were used in this study. For more details see Guo et al. (2014). Sequences of species in bold are unpublished and were provided by P. Guo as personal communication in Rediscovery of Andrea's keelback, Hebius andreae (Ziegler & Le, 2006): First country record for Laos and phylogenetic placement
GenBank accession numbers of the four marker genes and associated voucher specimens/tissues that were used in this study. For more details see Guo et al. (2014). Sequences of species in bold are unpublished and were provided by P. Guo as personal communication
Supporting data and code for "Brown AW, Bohan Brown MM, Onken KL, Beitz DC. Short-term consumption of sucralose, a nonnutritive sweetener, is similar to water with regard to select markers of hunger signaling and short-term glucose homeostasis in women. Nutr Res. 2011 Dec;31(12):882-8. doi: 10.1016/j.nutres.2011.10.004. PMID: 22153513."
<p>Data and code to support the publication, Brown AW, Bohan Brown MM, Onken KL, Beitz DC. Short-term consumption of sucralose, a nonnutritive sweetener, is similar to water with regard to select markers of hunger signaling and short-term glucose homeostasis in women. Nutr Res. 2011 Dec;31(12):882-8. doi: 10.1016/j.nutres.2011.10.004. PMID: 22153513.</p> <ul> <li>Code was updated 2020 NOV 24 to add comments, but otherwise remains unchanged from 2011.</li> <li>Data file was updated to include a data dictionary, but otherwise remains unchanged from 2011.</li> </ul> <p>Treatment identifiers for the four-arm crossover are clarified in the SAS code.</p> <p>Other details are available in the published article.</p>
Point, polygon, or marker? In search of the best geographic entity for mapping Cultural Ecosystem Services using the online PPGIS tool, "My Green Place."
<p>Excel files include the raw database and the processed data that led to the quadrat analyses. The "Matrix_raw data" file includes the raw data as downloaded from the server. This data was cleaned and organized for its posterior use. "Quadrat analyzes "file includes all the quadrat analyses resulting in each research question in the paper except question four. Question 4 can be seen in the file "Water analysis_Blaarmeersen." All excel files come with a "CODE" tab that describes each of the codes used, their meaning, and ways that were calculated where necessary. Two zip files include all the GIS files. The first one includes the GIS files from which "Matrix_raw data" was built from. The second folder includes the resulting maps from the quadrat analyses. In order to visualize them as in the paper, configure the symbology tab at the GIS software in quantile and the categories number, as shown in the paper.</p> <p>The production of the files in the "GIS_Processed data" folder was done via a repetitive line of commands in ArcGIS pro. The same process was followed for each one of the quadrat analysis described in the paper. Refer to "<a href="https://zenodo.org/api/files/72403e0b-78a9-4bbf-8dca-ed9b8702e3ae/Reproduction%20commands%20and%20parameters.pdf">Reproduction commands and parameters.pdf</a>" for further information.</p>
New genetic markers for Sapotaceae phylogenomics: more than 600 nuclear genes applicable from family to population levels
<p>Some tropical plant families, such as the Sapotaceae, have a complex taxonomy, which can be resolved using Next Generation Sequencing (NGS). For most groups however, methodological protocols are still missing. Here we identified 531 monocopy genes and 227 Short tandem repeats (STR) markers and tested them on Sapotaceae using target capture and NGS. The probes were designed using two genome skimming samples from<em>Capurodendron delphinense</em> and <em>Bemangidia lowryi</em>, both from the Tseboneae tribe, as well as the published <em>Manilkara zapota</em> transcriptome from the Sapotoideae tribe. We combined our probes with 261 additional ones previously published and designed for the entire angiosperm group. On a total of 792 low-copy genes, 638 showed no signs of paralogy and were used to build a phylogeny of the family with 231 individuals from all main lineages. A highly supported topology was obtained at high taxonomic ranks but also at the species level. This phylogeny revealed the existence of more than 20 putative new species. Single nucleotide polymorphisms (SNPs) extracted from the 638 genes were able to distinguish lineages within a species complex and to highlight geographical structuration. STR were recovered efficiently for the species used as reference (<em>C. delphinense</em>) but the recovery rate decreased dramatically with the phylogenetic distance to the focal species. All together, the new loci will help reaching a sound taxonomic understanding of the family Sapotaceae for which many circumscriptions and relationships are still debated, at the species, genus and tribe levels.</p>
Articles citing HIMF as marker for alternatively activated macrophages
<p>These articles offer good evidence that HIMF is a marker for alternatively activated macrophages.</p>
Data and script for: A marker of biological age explains individual variation in the strength of the adult stress response
<p>Data and script for: A marker of biological age explains individual variation in the strength of the adult stress response.</p> <p>Comprises 2 CSV data files and one R script.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.