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43 results for “mechanical isolation”
Data from: The role of prezygotic isolation mechanisms in the divergence of two parasite species
Background: The formation of reproductive barriers in diverging lineages is a prerequisite to complete speciation according to the biological species concept. In parasites with complex life cycles, speciation may be driven by adaptation to different intermediate hosts, yet diverging lineages can still share the same definitive host where reproduction takes place. In these cases, prezygotic isolation mechanisms should evolve very early and be particularly strong, preventing costly unfavourable matings. In this study, we investigated the importance of prezygotic barriers to reproduction in two cestode species that diverged 20–25mya and show an extraordinary degree of specificity to different intermediate hosts. Both species share the same definitive hosts and hybridize in the laboratory. Yet, natural hybrids have so far not been detected. Methods: We used a combination of different experiments to investigate the role of prezygotic barriers to reproduction in the speciation of these parasites. First, we investigated whether hybridization is possible under natural conditions by exposing lab-reared herring gulls (Larus argentatus, the definitive hosts) to both parasites of either sympatric or allopatric combinations. In a second experiment, we tested whether the parasites prefer conspecifics over parasites from a different species in dichotomous mate choice trials. Results: Our results show that the two species hybridize under natural conditions with parasites originating either from sympatric or allopatric populations producing hybrid offspring. Surprisingly, the mate choice experiment indicated that both parasite species prefer mates of the different species to conspecifics. Conclusions: Neither fundamental constraints against hybridization in a natural host nor assortative mate choice sufficiently explain the persistent segregation of the two tapeworm species in nature. Hence, postzygotic ecological selection against hybrids is presumably the more important driving force limiting gene flow between the two parasite sister species.
Data from: Behavioural mechanisms of sexual isolation involving multiple modalities and their inheritance
Speciation research dissects the genetics and evolution of reproductive barriers between parental species. Hybrids are the 'gatekeepers' of gene flow, so it is also important to understand the behavioural mechanisms and genetics of any potential isolation from their parental species. We tested the role of multiple behavioural barriers in reproductive isolation among closely related field crickets and their hybrids (Teleogryllus oceanicus and T. commodus). These species hybridise in the laboratory, but the behaviour of hybrids is unusual and there is little evidence for gene flow in the wild. We found that heterospecific pairs exhibited reduced rates of courtship behaviour due to discrimination by both sexes, and that this behavioural isolation was symmetrical. However, hybrids were not sexually selected against and exhibited high rates of courtship behaviour even though hybrid females are sterile. Using reciprocal hybrid crosses, we characterized patterns of interspecific divergence and inheritance in key sexual traits that might underlie the mating patterns we found: calling song, courtship song and cuticular hydrocarbons (CHCs). Song traits exhibited both sex-linkage and transgressive segregation, whereas CHCs exhibited only the latter. Calculations of the strength of isolation exerted by these sexual traits suggest that close-range signals are as important as long-distance signals in contributing to interspecific sexual isolation. The surprisingly weak mating barriers observed between hybrids and parental species highlights the need to examine reproductive isolating mechanisms and their genetic bases across different potential stages of introgressive hybridisation.
Isolating Mechanisms in the Treatment of Borderline Personality Disorder
ClinicalTrials.gov study NCT03408860. IPD Sharing: NO. Countries: 1. Publications: 0.
Characteristics of Lower Respiratory Tract Escherichia Coli Isolates in Mechanically Ventilated Intensive Care Patients
ClinicalTrials.gov study NCT03303937. IPD Sharing: UNDECIDED. Countries: 0. Publications: 5.
Data from: The role of prezygotic isolation mechanisms in the divergence of two parasite species
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Data from: Behavioural mechanisms of sexual isolation involving multiple modalities and their inheritance
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Topological isolation as a mechanism for precise control of developmental regulators in mammalian genomes [RNA-seq]
GEO Series GSE127194. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing.
Exploring comparative and transcriptomic analyses to unveil mechanisms of resistance to azoles dependent and independent of CgPdr1 in Candida glabrata clinical isolates
GEO Series GSE166841. Nakaseomyces glabratus. 14 samples. Type: Expression profiling by array.
Molecular and Cellular Mechanisms for Differential Effects of Chronic Social Isolation Stress in Males and Females
GEO Series GSE198725. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Topological isolation as a mechanism for precise control of developmental regulators in mammalian genomes [RNA-seq II]
GEO Series GSE165339. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
To determine the potential molecular mechanisms by which STAT5 signaling controls colonic crypt homeostasis, we isolated total RNA from ileal intact crypts of STAT5+/+, STAT5DIEC-/- and STAT5DIEC+++ m
GEO Series GSE112607. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Isolation and next generation sequencing of epididymal extracellular vesicles reveals segmental patterns of miRNA expression and a potential mechanism for modification of the sperm epigenome.
GEO Series GSE79500. Mus musculus. 9 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Topological isolation as a mechanism for precise control of developmental regulators in mammalian genomes
GEO Series GSE127196. Homo sapiens. 81 samples. Type: Expression profiling by high throughput sequencing; Other.
Phenotypic Profile and Molecular Mechanism of Resistance in Carbapenemase-producing Enterobacterales and Pseudomonas Aeruginosa Isolates From Brazilian Hospitals: Implications for the Introduction of
ClinicalTrials.gov study NCT05285046. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Neurobehavioral Mechanisms of Social Isolation and Loneliness in Serious Mental Illness
ClinicalTrials.gov study NCT04940663. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Topological isolation as a mechanism for precise control of developmental regulators in mammalian genomes (Hi-C II)
GEO Series GSE165375. Homo sapiens. 16 samples. Type: Other.
Data from: Hybridization, species collapse, and species reemergence after disturbance to premating mechanisms of reproductive isolation
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Transcriptomics analysis reveals the molecular mechanisms of the antibacterial activity of gallium nitrate against Acinetobacter baumannii isolated from bloodstream infections
GEO Series GSE194255. Acinetobacter baumannii. 6 samples. Type: Expression profiling by high throughput sequencing.
Topological isolation as a mechanism for precise control of developmental regulators in mammalian genomes [HiC]
GEO Series GSE130085. Homo sapiens. 17 samples. Type: Other.
Topological isolation as a mechanism for precise control of developmental regulators in mammalian genomes [4C-seq]
GEO Series GSE127195. Homo sapiens. 12 samples. Type: Other.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.