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Dataset results
79 results for “modifier model”
Ozone modified hypothalamic signaling enhancing thermogenesis in the TDP-43A315T transgenic model of Amyotrophic Lateral Sclerosis
<p><strong>Illumina sequencing and analysis</strong></p>
A Modified Global Plate Model Including Quantitative Tomotectonic Plate Reconstruction of Western North America and the Eastern Pacific Basin
<p>This plate model is based on that of Clennett et al. (2020) (<a href="../records/10348271" target="_blank" rel="noopener">https://zenodo.org/records/10348271</a>). The Clennett et al. (2020) model was an extension of the global model of Müller et al. (2019) (<a href="../records/10525287" target="_blank" rel="noopener">https://zenodo.org/records/10525287</a>), with a focus on producing a more detailed tectonic reconstruction of the North American Cordillera. Further minor modifications were made to the model for a paper by Alfonso et al. (2024), using the <em>GPlates</em> software (<a href="https://url.au.m.mimecastprotect.com/s/JVvZCE8wmrt1kqgwPtNcn8j?domain=gplates.org/" target="_blank" rel="noopener">https://www.gplates.org/</a>). Firstly, several subduction zones in the published plate model have no associated motions, instead remaining entirely stationary relative to the mantle. This was judged to be incompatible with basic geodynamic principles, as geodynamic models indicate that trenches and subducting slabs are almost always in motion relative to the mantle, exhibiting retreat or, more rarely, advance (e.g. Capitanio, 2013; Capitanio et al., 2010; Schellart et al., 2007; Stegman et al., 2010). As trenches of intermediate length generally display relatively slow retreat (Schellart, 2008), a small amount of trench rollback was imposed on the subduction zones in this model, whilst ensuring that they remained located above their associated tomographically-imaged slabs. Additionally, the Orcas plate (170–130 Ma), located within the Cordilleran archipelago, was split into two sections separated by an east-west trending mid-ocean ridge, consistent with the subsequent plate configuration after 130 Ma. This was done to improve the consistency of the plate motion model, which appeared to indicate divergence within the Orcas plate and convergence at its boundaries. Finally, the reconstruction’s absolute plate motion model was recalculated using the iterative optimisation workflow developed by Tetley et al. (2019).</p> <p> </p> <p>The agegrids associated with this model can be accessed from: <a href="https://repo.gplates.org/webdav/PlateModel_Age_SR_Grids/Alfonso_etal_2024_modClennettMuller/" target="_blank" rel="noopener">https://repo.gplates.org/webdav/PlateModel_Age_SR_Grids/Alfonso_etal_2024_modClennettMuller/</a></p> <p> </p>
The data for the work "Verification of the modified Bixon-Jortner-Plotnikov model by calculating rates of non-adiabatic transitions in aromatic compounds"
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Dataset for "Sources of organic aerosols in Europe: A modelling study using CAMx with modified volatility basis set scheme"
<p>Model data for figures in the publication "Sources of organic aerosols in Europe: A modelling study using CAMx with modified volatility basis set scheme"</p> <p>Jiang, J., Aksoyoglu, S., El-Haddad, I., Ciarelli, G., Denier van der Gon, H. A. C., Canonaco, F., Gilardoni, S., Paglione, M., Minguillón, M. C., Favez, O., Zhang, Y., Marchand, N., Hao, L., Virtanen, A., Florou, K., O’Dowd, C., Ovadnevaite, J., Baltensperger, U., and Prévôt, A. S. H.: Sources of organic aerosols in Europe: A modelling study using CAMx with modified volatility basis set scheme, Atmos. Chem. Phys., 2019.</p> <p> All the data are stored in .mat file, and the variable names are self-explanatory.</p> <p> </p> <p> </p> <p> </p>
Modified Fuchs et al. model Synthetic Data Sets
<p>Synthetic data sets used for machine learning of laser acceleration of protons</p>
Use of the Modified Beef Tongue Model for Teaching Repair of Obstetrical Fourth-Degree Laceration to Residents
ClinicalTrials.gov study NCT03341351. IPD Sharing: Not stated. Countries: 1. Publications: 3.
A Modified Mathematical Model to Calculate Power Received by Mechanically Ventilated Patients With Different Etiologies
ClinicalTrials.gov study NCT04046380. IPD Sharing: UNDECIDED. Countries: 1. Publications: 6.
A modified niche model for generating food webs with stage-structured consumers: The stabilizing effects of life-history stages on complex food webs
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Data from: Anthracycline drugs on modified surface of quercetin-loaded polymer nanoparticles: a dual drug delivery model for cancer treatment
Polymer nanoparticles are vehicles used for delivery of hydrophobic anti-cancer drugs, like doxorubicin, paclitaxel or chemopreventors like quercetin (Q). The present study deals with the synthesis and characterisation of nano formulations (NFs) from Q loaded PLGA (poly lactic-co-glycolic acid) nano particles (NPs) by surface modification. The surface of Q-loaded (NPs) is modified by coating with biopolymers like bovine serum albumin (BSA) or histones (His). Conventional chemotherapeutic drugs adriamycin (ADR) and mitoxantrone (MTX) are bound to BSA and His respectively before being coated on Q-loaded NPs to nano formulate NF1 and NF2 respectively. The sizes of these NFs are in the range 400-500 nm as ascertained by SEM and DLS measurements. Encapsulation of Q in polymer NPs is confirmed from shifts in FT-IR, TGA and DSC traces of Q-loaded NPs compared to native PLGA and Q. Surface modification in NFs is evidenced by three distinct regions in their TEM images; the core, polymer capsule and the coated surface. Negative zeta potential of Q-loaded NPs shifted to positive potential on surface modification in NF1 and NF2. In vitro release of Q from the NFs lasted up to twenty days with an early burst release. NF2 is better formulation than NF1 as loading of MTX is 85% compared to 23% loading of ADR. Such NFs are expected to overcome multi-drug resistance (MDR) by reaching and treating the target cancerous cells by virtue of size, charge and retention.
mTORC1/rpS6 signaling complex that modifies BTB transport function – an in vivo study using the adjudin model
<p>Supplement Data</p>
Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model
ClinicalTrials.gov study NCT00689078. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Prospective Randomised Control Trial to Study the Effectiveness of a Health Service Innovation Using a Modified Virtual Ward Model to Prevent Unscheduled Readmission of High Risk Patients
ClinicalTrials.gov study NCT02325752. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model
ClinicalTrials.gov study NCT01534195. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluation of the Fluoride Dose Response of a Modified In Situ Caries Model
ClinicalTrials.gov study NCT03383783. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluation of Prednisolone in a Modified Conjunctival Allergen Challenge Model
ClinicalTrials.gov study NCT01730872. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Data from: Forward modeling the rubber hand: illusion of ownership modifies motor-sensory predictions by the brain
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Data from: Anthracycline drugs on modified surface of quercetin-loaded polymer nanoparticles: a dual drug delivery model for cancer treatment
Open the record for dataset details and reuse information.
A mathematical model of flow-mediated coagulation identifies factor V as a modifier of thrombin generation in hemophilia A
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CARD9 attenuates Ab pathology and modifies microglial responses in an Alzheimer’s disease mouse model
GEO Series GSE232636. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation [bulk RNA-seq]
GEO Series GSE255902. Homo sapiens. 19 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.