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239
datasets available to search
ShareScore release 0.9.0
Dataset results
239 results for “mycophenolate mofetil”
Mycophenolate Mofetil and Tacrolimus Versus Tacrolimus for the Treatment of Idiopathic Membranous Glomerulonephritis
ClinicalTrials.gov study NCT00843856. IPD Sharing: NO. Countries: 1. Publications: 2.
Tacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTX
ClinicalTrials.gov study NCT00360685. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study to Evaluate the Efficacy and Safety of Rituximab Versus Mycophenolate Mofetil (MMF) in Participants With Pemphigus Vulgaris (PV)
ClinicalTrials.gov study NCT02383589. IPD Sharing: Not stated. Countries: 12. Publications: 1.
High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Dono
ClinicalTrials.gov study NCT03128359. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study to Assess the Effect of CellCept (Mycophenolate Mofetil) and Reduced Corticosteroids in Patients With Active Pemphigus Vulgaris (PV)
ClinicalTrials.gov study NCT00683930. IPD Sharing: Not stated. Countries: 8. Publications: 1.
Dataset related to article "Dose-Dependent Impairment of the Immune Response to the Moderna-1273 mRNA Vaccine by Mycophenolate Mofetil in Patients with Rheumatic and Autoimmune Liver Diseases"
<p>This record contains data related to article “Dose-Dependent Impairment of the Immune Response to the Moderna-1273 mRNA Vaccine by Mycophenolate Mofetil in Patients with Rheumatic and Autoimmune Liver Diseases”</p> <p>The purpose of this study was to evaluate the efficacy and safety of the Moderna-1273 mRNA vaccine for SARS-CoV-2 in patients with immune-mediated diseases under different treatments. Anti-trimeric spike protein antibodies were tested in 287 patients with rheumatic or autoimmune diseases (10% receiving mycophenolate mofetil, 15% low-dose glucocorticoids, 21% methotrexate, and 58% biologic/targeted synthetic drugs) at baseline and in 219 (76%) 4 weeks after the second Moderna-1273 mRNA vaccine dose. Family members or caretakers were enrolled as the controls. The neutralizing serum activity against SARS-CoV-2-G614, alpha, and beta variants in vitro and the cytotoxic T cell response to SARS-CoV-2 peptides were determined in a subgroup of patients and controls. Anti-SARS-CoV-2 antibody development, i.e., seroconversion, was observed in 69% of the mycophenolate-treated patients compared to 100% of both the patients taking other treatments and the controls (<em>p</em> &lt; 0.0001). A dose-dependent impairment of the humoral response was observed in the mycophenolate-treated patients. A daily dose of &gt;1 g at vaccination was a significant risk factor for non-seroconversion (ROC AUC 0.89, 95% CI 0.80-98, <em>p</em> &lt; 0.0001). Moreover, in the seroconverted patients, a daily dose of &gt;1 g of mycophenolate was associated with significantly lower anti-SARS-CoV-2 antibody titers, showing slightly reduced neutralizing serum activity but a comparable cytotoxic response compared to other immunosuppressants. In non-seroconverted patients treated with mycophenolate at a daily dose of &gt;1 g, the cytotoxic activity elicited by viral peptides was also impaired. Mycophenolate treatment affects the Moderna-1273 mRNA vaccine immunogenicity in a dose-dependent manner, independent of rheumatological disease.</p> <p>.</p>
Study to Evaluate the Safety and Efficacy of Extended Release Tacrolimus (Advagraf®) + Sirolimus (Rapamune®), Versus Extended Release Tacrolimus (Advagraf®) + Mycophenolate Mofetil in Kidney Transplan
ClinicalTrials.gov study NCT01680952. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Comparison of Mycophenolate Mofetil and Cyclophosphamide for Active Takayasu's Arteritis
ClinicalTrials.gov study NCT03096275. IPD Sharing: NO. Countries: 1. Publications: 6.
Intensified Dosing of Cellcept (Mycophenolate Mofetil) in Kidney Transplantation
ClinicalTrials.gov study NCT00943228. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Mycophenolate Mofetil (MMF) Versus Intravenous CTX Pulses in the Treatment of Adult Severe HSPN
ClinicalTrials.gov study NCT00301613. IPD Sharing: Not stated. Countries: 1. Publications: 1.
CLEAR Study - A Study of CellCept (Mycophenolate Mofetil) in Recipients of Kidney Transplants
ClinicalTrials.gov study NCT00788567. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effects of Mycophenolate Mofetil (MMF) on Surrogate Markers for Cardiovascular Disease in HIV-1 Infected Patients
ClinicalTrials.gov study NCT00247494. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Compare Efficacy and Safety of Repeated Courses of Rituximab to That of Maintenance Mycophenolate Mofetil Following Single Course of Rituximab Among Children With Steroid Dependent Nephrotic Syndrome
ClinicalTrials.gov study NCT03899103. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
Mycophenolate Mofetil in Membranous Nephropathy and Focal Segmental
ClinicalTrials.gov study NCT00404833. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Effectiveness of Mycophenolate Mofetil Combined With Tacrolimus for Steroid Tapering in Systemic Lupus Erythematosus
ClinicalTrials.gov study NCT05916781. IPD Sharing: NO. Countries: 1. Publications: 13.
Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant
ClinicalTrials.gov study NCT00078858. IPD Sharing: Not stated. Countries: 3. Publications: 1.
Study to Compare the Pharmacokinetics of Mycophenolate Mofetil Metabolites From Four Tablet Formulations in Healthy Participants
ClinicalTrials.gov study NCT02981290. IPD Sharing: NO. Countries: 1. Publications: 1.
Observational Study of the Combination of Post-transplant High Dose Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for the Prevention of Acute Graft-versus-Host Disease in Patients Eligible to
ClinicalTrials.gov study NCT02300571. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Mycophenolate Mofetil to Treat Wegener's Granulomatosis and Related Vascular Inflammatory Conditions
ClinicalTrials.gov study NCT00001764. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Mycophenolate Mofetil for IgA Nephropathy
ClinicalTrials.gov study NCT00863252. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
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OpenNeuro
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