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60 results for “nanobodies”
Accompanying images to the paper NLR immune receptor–nanobody fusions confer plant disease resistance
<p>The following images accompany the paper <strong>NLR immune receptor–nanobody fusions confer plant disease resistance</strong>, Kourelis J., Marchal C., Posbeyikian A., Harant A., Kamoun S. (2023) Science Vol. 379, No. 6635. <a href="https://doi.org/10.1126/science.abn4116">DOI: 10.1126/science.abn4116</a></p> <p> </p> <p><strong>Figure captions:</strong></p> <p><strong>Figure 1. </strong>Leaves photographed 12 days after infection with a Potato Virus X variant expressing the fluorescent protein EGFP. Left: <em>Nicotiana benthamiana</em> leaf that doesn't express the pikobody system. Right: Leaf from <em>N. benthamiana</em> line stably expressing the Pikobody system recognizing EGFP. </p> <p><strong>Figure 2. </strong>Leaves photographed 12 days after infection with a Potato Virus X variant expressing the fluorescent protein mCherry. Both leaves correspond to a <em>N. benthamiana</em> line stably expressing the Pikobody system recognizing EGFP. These results accompany the observations that the Pikobody system targetting EGFP specifically recognizes EGFP, but not mCherry.</p> <p><strong>Figure 3. </strong>Side by side comparison of representative adult <em>N. benthamiana</em> plants, from left to right: wild-type (WT), stably transformed with the rice NLR pair Pikm-1/2 (Pikm) or Pikobody<sup>Enhancer </sup>(Lines #4 - #1 - #9 - #10). </p>
Multiple Ascending Dose Trial of MSB0010841 (Anti-IL17A/F Nanobody) in Psoriasis Subjects
ClinicalTrials.gov study NCT02156466. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Treatment of Type 1 Diabetes With Anti-OX40L Bispecific With Anti-TNF Activity In a Single Nanobody® Molecule
ClinicalTrials.gov study NCT06812988. IPD Sharing: YES. Countries: 8. Publications: 0.
DNA G-Quadruplex Recognition In Vitro and in Live Cells by a Structure-Specific Nanobody
GEO Series GSE207567. Homo sapiens. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Nanobody-tethered transposition enables multifactorial chromatin profiling at single-cell resolution
GEO Series GSE212588. Homo sapiens. 17 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Nanobodies agains Sars Cov 2 Nsp9 protein protects cells from virus infection
GEO Series GSE244714. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing.
Multimodal chromatin profiling using nanobody-based single-cell CUT&Tag
GEO Series GSE198467. Mus musculus. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Construction of Synthetic Nanobody Library in Mammalian Cells by dsDNA-Based Strategies
GEO Series GSE158906. Homo sapiens. 8 samples. Type: Other.
Multimeric nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants
GEO Series GSE167310. Mus musculus; Lama glama. 11 samples. Type: Other.
Framework humanization increases the affinity and potency of anti-CD72 nanobody-based CAR-T cells for B-cell malignancies
GEO Series GSE218791. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Generation of synthetic Acinetobacter baumannii specific nanobodies
GEO Series GSE202972. Escherichia coli. 3 samples. Type: Other.
Nanobody-based in vivo blockade of the P2X7 ion channel uncovers a hitherto unknown large subpopulation of parenchymal kidney TRM and NKT cells
GEO Series GSE241191. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Nanobody-tethered transposition for dual profiling of chromatin accessibility and DNA methylation
GEO Series GSE278068. Mus musculus; Homo sapiens. 201 samples. Type: Methylation profiling by high throughput sequencing; Other.
PD-L2 Targeting Nanobody Radiotracer for PET Imaging of Solid Tumor
ClinicalTrials.gov study NCT05803746. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Nanobody-Based CD19/CD22 Tandem Dual CAR-T Therapy for R/R B-ALL
ClinicalTrials.gov study NCT06880913. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
First in Man Study of ALX-0651, a Nanobody Inhibiting CXCR4
ClinicalTrials.gov study NCT01374503. IPD Sharing: Not stated. Countries: 1. Publications: 0.
CD19/20 Bispecific Nanobody-derived CAR-T Cells in B Cell Lymphoma
ClinicalTrials.gov study NCT03881761. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study to Assess Safety and Efficacy of Anti-Interleukin 6-receptor (IL6R) Nanobody in Rheumatoid Arthritis (RA) Patients
ClinicalTrials.gov study NCT01284569. IPD Sharing: Not stated. Countries: 3. Publications: 0.
CD147 Targeting Nanobody Probe for PET Imaging in Solid Tumors
ClinicalTrials.gov study NCT06646952. IPD Sharing: NO. Countries: 1. Publications: 0.
First-in-Human Trial of Anti-ADAMTS-5 Nanobody in Healthy Volunteers
ClinicalTrials.gov study NCT03224702. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.