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154
datasets available to search
ShareScore release 0.9.0
Dataset results
154 results for “off-target”
A mouse model for assessing mTOR kinase-independent role and off-target effect of mTOR kinase inhibitors
GEO Series GSE172250. Mus musculus. 41 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Sensitive and unbiased genome-wide profiling of base-editor-induced off-target activity with CHANGE-seq-BE [CHANGE-seq-BE for CD40L target]
GEO Series GSE298465. Homo sapiens. 3 samples. Type: Other.
Whole exome sequencing analyzed the off-target effect of gene editing through BE3 system.
GEO Series GSE115017. Mus musculus. 14 samples. Type: Genome variation profiling by high throughput sequencing.
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen]
GEO Series GSE121666. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Methylone is a rapid-acting neuroplastogen with less off-target activity than MDMA
GEO Series GSE253280. Rattus norvegicus. 36 samples. Type: Expression profiling by high throughput sequencing.
Characterization of gRNA-Dependent and gRNA-Independent Off-Target Binding Sites of PspCas13b and RfxCas13d in Mammalian Cells [CLIP-seq]
GEO Series GSE291436. Homo sapiens. 47 samples. Type: Other.
An siRMSD parameter of structural distortion induced by chemical modification is predictive of the off-target effect of siRNA_(2/2)
GEO Series GSE278439. Homo sapiens. 4 samples. Type: Expression profiling by array.
Off-target effect of CWG-cPIP on gene expression of mouse hippocampus
GEO Series GSE235801. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Estimating Genome-wide Off-Target Effects for Pyrrole-Imidazole Polyamide Binding by a Pathway-Based Expression Profiling Approach (MC-IXC cells)
GEO Series GSE124458. Homo sapiens. 6 samples. Type: Expression profiling by array.
Alteration of target cleavage patterns and off-target reduction of antisense oligonucleotides incorporating 2-N-carbamoyl- or (2-pyridyl)guanine
GEO Series GSE228747. Homo sapiens. 24 samples. Type: Expression profiling by array.
Massively targeted evaluation of therapeutic CRISPR off-targets in cells
GEO Series GSE206347. Homo sapiens. 702 samples. Type: Other.
Characterization of off-target effects of a first-in-class EGFR-directed KRAS G12V selective inhibitor, EFTX-G12V, in SKCO1 cells.
GEO Series GSE278020. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Characterization of gRNA-Dependent and gRNA-Independent Off-Target Binding Sites of PspCas13b and RfxCas13d in Mammalian Cells [RNA-Seq]
GEO Series GSE291437. Homo sapiens. 66 samples. Type: Expression profiling by high throughput sequencing.
Estimating Genome-wide Off-Target Effects for Pyrrole-Imidazole Polyamide Binding by a Pathway-Based Expression Profiling Approach
GEO Series GSE124462. Homo sapiens. 40 samples. Type: Expression profiling by array.
Genome-wide determination of on-target and off-target characteristics for RNA-guided DNA Methylation by dCas9 methyltransferases (CRISPRme) [ChIP-Seq]
GEO Series GSE92261. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Omics analyses of mouse constitutive androstane receptor (CAR) ligand TCPOBOP effects in humanized mice reveal off-target lipid metabolism disruption
GEO Series GSE186654. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements
GEO Series GSE131349. Homo sapiens. 104 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Other.
Off-Target RNA editing induced by RECODE in Mouse Quadratus Femoris Muscle
GEO Series GSE307453. Mus musculus. 9 samples. Type: Other.
Synthesis of 2'-formamidonucleoside phosphoramidites for suppressing the seed-based off-target effects of siRNAs
GEO Series GSE274299. Homo sapiens. 8 samples. Type: Expression profiling by array.
Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease
GEO Series GSE55887. Homo sapiens. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.