Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
87
datasets available to search
ShareScore release 0.7.1
Dataset results
87 results for “olfactory bulb”
Dendritic integration in olfactory bulb granule cells upon simultaneous multi-spine activation: Low thresholds for non-local spiking activity
<p class="CxSpFirst">The inhibitory axonless olfactory bulb granule cells form reciprocal dendrodendritic synapses with mitral and tufted cells via large spines, mediating recurrent and lateral inhibition. As a case in point for dendritic transmitter release, rat granule cell dendrites are highly excitable, featuring local Na<sup>+</sup> spine spikes and global Ca<sup>2+</sup>- and Na<sup>+</sup>-spikes. To investigate the transition from local to global signaling we performed holographic, simultaneous two-photon uncaging of glutamate at up to twelve granule cell spines, along with whole-cell recording and dendritic two-photon Ca<sup>2+</sup> imaging in acute juvenile rat brain slices. Coactivation of less than ten reciprocal spines was sufficient to generate diverse regenerative signals that included regional dendritic Ca<sup>2+</sup>-spikes and dendritic Na<sup>+</sup>-spikes (D-spikes). Global Na<sup>+</sup>-spikes could be triggered in one third of granule cells. Individual spines and dendritic segments sensed the respective signal transitions as increments in Ca<sup>2+</sup> entry. Dendritic integration as monitored by the somatic membrane potential was mostly linear until a threshold number of spines was activated, where often D-spikes along with supralinear summation set in. As to the mechanisms supporting active integration, NMDA receptors strongly contributed to all aspects of supralinearity, followed by dendritic voltage-gated Na<sup>+</sup>- and Ca<sup>2+</sup>-channels, whereas local Na<sup>+</sup> spine spikes as well as morphological parameters barely mattered.</p> <p>Because of the low numbers of coactive spines required to trigger dendritic Ca<sup>2+</sup> signals and thus possibly lateral release of GABA onto mitral and tufted cells, we predict that thresholds for granule cell-mediated bulbar lateral inhibition are low. Moreover, D-spikes could provide a plausible substrate for granule cell-mediated gamma oscillations.</p>
Dendritic integration in olfactory bulb granule cells upon simultaneous multi-spine activation: Low thresholds for non-local spiking activity
Open the record for dataset details and reuse information.
Open housing drives the expression of immune-response genes in the nasal mucosa, but not the olfactory bulb
GEO Series GSE102457. Mus musculus. 60 samples. Type: Expression profiling by high throughput sequencing.
Single cell RNAseq of mouse olfactory bulb reveals cellular heterogeneity and activity dependent molecular census of adult-born neurons
GEO Series GSE121891. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Differential Gene Expression Analysis with Altered Local CRH Signaling in the Mouse Olfactory Bulb
GEO Series GSE98799. Mus musculus. 15 samples. Type: Expression profiling by array.
WGBS from olfactory bulb (ENCSR334YHO)
GEO Series GSE187185. Mus musculus. 4 samples. Type: Methylation profiling by high throughput sequencing.
Transcriptional profiling of CD11b+ microglia isolated from cerebellum and olfactory bulb-removed brains of SAMP8 and SAMR1 mice at 2, 5, and 9 months of age.
GEO Series GSE253582. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing; Other.
Temporal and dosage-dependent transcriptional response to SARS-CoV-2 in lung, trachea, brain, olfactory bulb and small intestine of Syrian golden hamsters
GEO Series GSE161200. Mesocricetus auratus. 215 samples. Type: Expression profiling by high throughput sequencing.
Transcription Factors Dlx1/2 Are Required for Making All Interneurons in the Olfactory Bulb [Pax6]
GEO Series GSE121213. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Molecular diversity of olfactory bulb projection neurons
GEO Series GSE162656. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
olfactory bulb from control mouse and a mouse with developmentally-induced olfactory bulb degeneration
GEO Series GSE241951. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Gene Expression Profiles of Adult Human Olfactory Bulb and Embryonic Neural Stem Cells
GEO Series GSE35390. Homo sapiens. 9 samples. Type: Expression profiling by array.
Genome-wide expression analysis of E18.5 and P30 olfactory bulbs of control and Tshz1 mutant mice
GEO Series GSE51761. Mus musculus. 32 samples. Type: Expression profiling by array.
Transcriptome analysis in the olfactory bulb of high-fat diet-fed mice
GEO Series GSE277760. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcription Factors Dlx1/2 Are Required for Making All Interneurons in the Olfactory Bulb [Dlx1/2]
GEO Series GSE121214. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Gene expression changes in the olfactory bulb of mice induced by exposure to diesel exhaust are dependent on animal rearing environment
GEO Series GSE46163. Mus musculus. 8 samples. Type: Expression profiling by array.
Early synergy between IFNγ-inducible Gbp4 and Irgb6 in the olfactory bulb contributes to experimental cerebral malaria pathology
GEO Series GSE282591. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
Single-cell RNA sequencing (scRNAseq) data from Ventricular-Subventricular Zone (V-SVZ) and Olfactory Bulb (OB) cells, and Scope-Seq data from Ventricular-Subventricular Zone (V-SVZ)
GEO Series GSE134918. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing.
An olfactory bulb GnRH neuronal population translates social relevant odors into reproductive behavior in male mice
GEO Series GSE268138. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia (scRNA-seq: olfactory bulb)
GEO Series GSE148360. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.