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31
datasets available to search
ShareScore release 0.7.1
Dataset results
31 results for “prefrontal activity”
Complement and microglia activation mediates stress-induced synapse loss in layer 2/3 of the medial prefrontal cortex
GEO Series GSE272813. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
KCNH2-3.1 mediates aberrant complement activation to impair hippocampal-medial prefrontal pathway associated with schizophrenia
GEO Series GSE118989. Mus musculus. 69 samples. Type: Expression profiling by high throughput sequencing.
Electrophysiological recordings from: Effects of Acute Stress on the Oscillatory Activity of the Hippocampus-Amygdala-Prefrontal Cortex Network. Merino et al. 2021
<p>Electrophysiological recordings of local field potentials (LFP) from infralimbic cortex (IL), basolateral amygdala (BLA) and dorsal hippocampus (dHPC). These data are collected from urethane-anesthetized rats. </p><p><strong>Abstract:</strong></p><p>Displaying a stress response to threatening stimuli is essential for survival. These reactions must be adjusted to be adaptive. Otherwise, even mental illnesses may develop. Describing the physiological stress response may contribute to distinguishing the abnormal responses that accompany the pathology, which may help to improve the development of both diagnoses and treatments. Recent advances have elucidated many of the processes and structures involved in stress response management; however, there is still much to unravel regarding this phenomenon. The main aim of the present research is to characterize the response of three brain areas deeply involved in the stress response (i.e., to an acute stressful experience). Specifically, the electrophysiological activity of the infralimbic division of the medial prefrontal cortex (IL), the basolateral nucleus of the amygdala (BLA), and the dorsal hippocampus (dHPC) was recorded after the infusion of 0.5 µl of corticosterone-releasing factor into the dorsal raphe nucleus (DRN), a procedure which has been validated as a paradigm to cause acute stress. This procedure induced a delayed reduction in slow waves in the three structures, and an increase in faster oscillations, such as those in theta, beta, and gamma bands. The mutual information at low theta frequencies between the BLA and the IL increased, and the delta and slow wave mutual information decreased. The low theta-mid gamma phase-amplitude coupling increased within BLA, as well as between BLA and IL. This electrical pattern may facilitate the activation of these structures, in response to the stressor, and memory consolidation. </p>
Prefrontal Brain Activity and ECG Patterns in Stroke and Healthy Adults
ClinicalTrials.gov study NCT07322107. IPD Sharing: NO. Countries: 1. Publications: 0.
The Activation and Walking Speed of the Prefrontal Cortex of the Elderly Mild Cognitive Impairment During Dual Task.
ClinicalTrials.gov study NCT05885867. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Modification of the Activity of the Prefrontal Cortex by Virtual Distraction in the Lumbago
ClinicalTrials.gov study NCT04007302. IPD Sharing: NO. Countries: 1. Publications: 0.
The Activation on Prefrontal Cortex With Acupuncture and Moxibustion for Major Depressive Disorder: A Study of Functional Near Infrared Spectroscopy
ClinicalTrials.gov study NCT04272476. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Selective oxytocin receptor activation prevents prefrontal circuit dysfunction and social behavioral alterations in response to chronic prefrontal cortex activation in rats
GEO Series GSE246666. Rattus norvegicus. 12 samples. Type: Expression profiling by high throughput sequencing.
Comparison of the Efficacy of Transcranial Direct Current Stimulation (tDCS) of the Primary Motor Cortex (M1) or the Prefrontal Cortex Combined With Aerobic Activity for Alleviation of Fibromyalgia Sy
ClinicalTrials.gov study NCT06263972. IPD Sharing: NO. Countries: 0. Publications: 0.
Effects of attenuating astrocytic Ca2+ activity in the medial prefrontal cortex with iβARK on transcriptional profiles in 5xFAD mice (snRNA-seq)
GEO Series GSE304073. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Fluconazole reverses SHANK3-related autism-like deficits via lipid raft-driven IGF1R activation and prefrontal circuit remodeling
GEO Series GSE313444. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.