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46 results for “reference population”
Establishment of Reference Values for Insulin-like Growth Factor 1 (IGF1) in the General Population
ClinicalTrials.gov study NCT01831648. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Reference Values of Aerobic Fitness in the Contemporary Paediatric Population
ClinicalTrials.gov study NCT04876209. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Data from: Estimating the molecular evolutionary rates of mitochondrial genes referring to Quaternary Ice Age events with inferred population expansions and dispersals in Japanese Apodemus
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Data from: Complete blood count reference intervals from a healthy adult urban population in Kenya
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Data from: Using a reference population yardstick to calibrate and compare genetic diversity reported in different studies: an example from the brown bear.
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Reference population and gametophyte culture genotypes
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Data from: Genetic variation at aryl hydrocarbon receptor (AHR) loci in populations of Atlantic killifish (Fundulus heteroclitus) inhabiting polluted and reference habitats
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Reference allele frequencies for populations pools of Atlantic Herring (Clupea harengus)
<p>Atlantic herring is widespread in North Atlantic and adjacent waters and is one of the most abundant vertebrates on earth. This species is well suited to explore genetic adaptation due to minute genetic differentiation at selectively neutral loci. Here we report hundreds of loci underlying ecological adaptation to different geographic areas and spawning conditions. Four of these represent megabase inversions confirmed by long read sequencing. The genetic architecture underlying ecological adaptation in herring deviates from expectation under a classical infinitesimal model for complex traits because of large shifts in allele frequencies at hundreds of loci under selection.</p>
Data from: Loci contributing to boric acid toxicity in two reference populations of Drosophila melanogaster
Populations maintain considerable segregating variation in the response to toxic, xenobiotic compounds. To identify variants associated with resistance to boric acid, a commonly-used household insecticide with a poorly understood mechanism of action, we assayed thousands of individuals from hundreds of strains. Using the Drosophila Synthetic Population Resource (DSPR), a multi-parental population (MPP) of inbred genotypes, we mapped six QTL to short genomic regions containing few protein-coding genes (3–188), allowing us to identify plausible candidate genes underlying resistance to boric acid toxicity. One interval contains multiple genes from the cytochrome P450 family, and we show that ubiquitous RNAi of one of these genes, Cyp9b2, markedly reduces resistance to the toxin. Resistance to boric acid is positively correlated with caffeine resistance. The two phenotypes additionally share a pair of QTL, potentially suggesting a degree of pleiotropy in the genetic control of resistance to these two distinct xenobiotics. Finally, we screened the Drosophila Genetic Reference Panel (DGRP) in an attempt to identify sequence variants within mapped QTL that are associated with boric acid resistance. The approach was largely unsuccessful, with only one QTL showing any associations at QTL-specific 20% False Discovery Rate (FDR) thresholds. Nonetheless, these associations point to a potential candidate gene that can be targeted in future validation efforts. Although the mapping data resulting from the two reference populations do not clearly overlap, our work provides a starting point for further genetic dissection of the processes underlying boric acid toxicity in insects.
Study of Purified Vero Rabies Vaccine Compared With a Reference Rabies Vaccine as Simulated Rabies Post-Exposure Prophylaxis in Adult and Pediatric Population in Thaïland
ClinicalTrials.gov study NCT04478084. IPD Sharing: YES. Countries: 1. Publications: 0.
Data from: "Development of the draft genome sequence of the marbled flounder Pseudopleuronectes yokohamae as a reference of population genomic analysis" in Genomic Resources Notes accepted 1 February 2015 – 31 March 2015
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Data from: Loci contributing to boric acid toxicity in two reference populations of Drosophila melanogaster
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Reference allele frequencies for populations pools of Atlantic Herring (Clupea harengus)
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Inference of differentiation time for single cell transcriptomes using cell population reference data
GEO Series GSE85234. Mus musculus. 113 samples. Type: Expression profiling by high throughput sequencing.
3D chromatin architecture of drug-tolerant cancer cells at single-cell resolution (Reference dataset of population cells)
GEO Series GSE195810. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
System genetics in rat HXB/BXH reference population identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose
GEO Series GSE160361. Rattus norvegicus. 40 samples. Type: Expression profiling by high throughput sequencing.
SNIF (Sniff Nasal Inspiratory Force) Reference Values Of Mediterranean Population
ClinicalTrials.gov study NCT01886339. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Fetal Magnetic Resonance Imaging: Z-score Reference Ranges for a Large Patient Population in Normal Neuroimaging Measurement
ClinicalTrials.gov study NCT07004283. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Reference Population for Speckle Tracking Imaging
ClinicalTrials.gov study NCT01526252. IPD Sharing: NO. Countries: 1. Publications: 0.
Reference Interval Validation of High-Sensitivity Cardiac Troponin T Assay in Thai Population
ClinicalTrials.gov study NCT03968016. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.