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Dataset results
361 results for “respiratory disease”
A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease
ClinicalTrials.gov study NCT04908683. IPD Sharing: YES. Countries: 14. Publications: 1.
Does Pulmonary Rehabilitation Improve Balance in People With Respiratory Disease?
ClinicalTrials.gov study NCT00864084. IPD Sharing: Not stated. Countries: 1. Publications: 1.
History of coronavirus naming during the three zoonotic outbreaks in relation to virus taxonomy and diseases caused by these viruses. According to the current international classification of diseases49, MERS and SARS are classified as 1D64 and 1D65, respectively. in The species Severe acute respiratory syndromerelated coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
History of coronavirus naming during the three zoonotic outbreaks in relation to virus taxonomy and diseases caused by these viruses. According to the current international classification of diseases49, MERS and SARS are classified as 1D64 and 1D65, respectively.
Data from: Occurrence and phylogenetic analysis of bovine respiratory syncytial virus in outbreaks of respiratory disease in Norway
Background: Bovine respiratory syncytial virus (BRSV) is one of the major pathogens involved in the bovine respiratory disease (BRD) complex. The seroprevalence to BRSV in Norwegian cattle herds is high, but its role in epidemics of respiratory disease is unclear. The aims of the study were to investigate the etiological role of BRSV and other respiratory viruses in epidemics of BRD and to perform phylogenetic analysis of Norwegian BRSV strains. Results: BRSV infection was detected either serologically and/or virologically in 18 (86%) of 21 outbreaks and in most cases as a single viral agent. When serology indicated that bovine coronavirus and/or bovine parainfluenza virus 3 were present, the number of BRSV positive animals in the herd was always higher, supporting the view of BRSV as the main pathogen. Sequencing of the G gene of BRSV positive samples showed that the current circulating Norwegian BRSVs belong to genetic subgroup II, along with other North European isolates. One isolate from an outbreak in Norway in 1976 was also investigated. This strain formed a separate branch in subgroup II, clearly different from the current Scandinavian sequences. The currently circulating BRSV could be divided into two different strains that were present in the same geographical area at the same time. The sequence variations between the two strains were in an antigenic important part of the G protein. Conclusion: The results demonstrated that BRSV is the most important etiological agent of epidemics of BRD in Norway and that it often acts as the only viral agent. The phylogenetic analysis of the Norwegian strains of BRSV and several previously published isolates supported the theory of geographical and temporal clustering of BRSV.
Quantitative comparison of respiratory aerosol implicates speech as a principal driver in asymptomatic transmission of airborne disease
<p>Video recordings of breath and speech droplets. </p> <p>The first set of recordings shows breath droplets, enlarged in size due to nucleated condensation, while crossing a 0.7-mm thickness light-sheet at the original recording speed (120 f/s) and in slow motion (24 f/s).</p> <p>The second set of recordings shows droplets generated by speaking a single word, ‘popeye’, while traversing a low intensity (~0.1W/cm<sup>2</sup>) light-sheet of 13 mm thickness. The recordings are shown at the original recording speed (120 f/s), in slow motion (24 f/s) and after background subtraction of Raleigh scattering and other time-invariant sources of light.</p>
Modeling management strategies for chronic disease in wildlife: predictions for the control of respiratory disease in bighorn sheep
<p>1. Controlling persistent infectious disease in wildlife populations is an on-going challenge for wildlife managers and conservationists worldwide.</p> <p>2. Here, we develop a dynamic pathogen transmission model capturing key features of M. ovipneumoniae infection, a major cause of population declines in North American bighorn sheep (Ovis canadensis). We explore the effects of model assumptions and parameter values on disease dynamics, including density versus frequency dependent transmission, the inclusion of a carrier class versus a longer infectious period, host survival rates, disease-induced mortality and recovery rates, and the epidemic growth rate.</p> <p>3. We compare the effectiveness of a suite of management actions following an epidemic, including test-and-remove, depopulation-and-reintroduction, range expansion, herd augmentation, and density reduction.</p> <p>4. Our results suggest that test-and-remove, depopulation-and-reintroduction, and range expansion have the potential to facilitate recovery of persistently infected bighorn sheep herds post-epidemic. By contrast, augmentation could lead to worse outcomes than those expected in the absence of management. Management that improves host survival or reduces disease-induced mortality are also likely to improve population size and persistence of chronically infected herds.</p> <p>5. Dynamic transmission models like the one employed here offer a structured, logical approach towards exploring hypotheses and can serve as a basis for planning field experiments and adaptive management. Models should be used iteratively with the field empirical approaches to triangulate on better approaches to wildlife management.</p>
The appendix for dynamic model of respiratory infectious disease transmission by population mobility based on city network
<p>First, a scale-free city network was established, and the shortest path between any two nodes was determined. Second, the movement path of tourists was designed based on the shortest path. Subsequently, every infected person's information, such as the city, infection time, onset, and hospitalisation, was confirmed based on their movement path. Third, the features of the transmission path and time distribution of the epidemic were characterised after summarising the information. Finally, the reliability of the model was verified.</p>
Assessing Functional Capacity in Directly and Remotely Monitored Home-based Settings: A Protocol for a Multinational Validation Study in Individuals With Chronic Respiratory Diseases
ClinicalTrials.gov study NCT06447831. IPD Sharing: UNDECIDED. Countries: 2. Publications: 1.
ELECTROVEST: Electro-Stimulation Vibratory Vest for Pulmonary Rehabilitation in Patients With Chronic Respiratory Diseases
ClinicalTrials.gov study NCT07175012. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Controlled evaLuation of Angiotensin Receptor Blockers for COVID-19 respIraTorY Disease
ClinicalTrials.gov study NCT04394117. IPD Sharing: YES. Countries: 2. Publications: 3.
Acoustic Cough Monitoring for the Management of Patients With Known Respiratory Disease
ClinicalTrials.gov study NCT05042063. IPD Sharing: YES. Countries: 1. Publications: 14.
Respiratory Proprioceptive Neuromuscular Facilitation Technique in Chronic Pulmonary Obstructive Disease Patients.
ClinicalTrials.gov study NCT05876403. IPD Sharing: NO. Countries: 1. Publications: 4.
Effect of Acetazolamide on Right Ventricular Function at Rest in Patients With Respiratory Disease at Altitude
ClinicalTrials.gov study NCT03173508. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Effects of Lactobacillus Casei on Respiratory and Gastrointestinal Diseases in Adults
ClinicalTrials.gov study NCT02541539. IPD Sharing: Not stated. Countries: 1. Publications: 1.
HR-lowering Efficacy and Respiratory Safety of Ivabradine in Patients With Obstructive Airway Disease
ClinicalTrials.gov study NCT01365286. IPD Sharing: Not stated. Countries: 1. Publications: 36.
Effects of Respiratory Muscle Training and Respiratory Exercise in Exercise Tolerance, Performing Daily Life Activities and Quality of Life of Patients With Chronic Obstructive Pulmonary Disease
ClinicalTrials.gov study NCT01510041. IPD Sharing: Not stated. Countries: 1. Publications: 8.
(Re)Vitalizing Pulmonary Rehabilitation for Patients With Chronic Respiratory Diseases
ClinicalTrials.gov study NCT03799666. IPD Sharing: NO. Countries: 1. Publications: 3.
Vitamin D Supplementation in Critically Ill Children With Respiratory Diseases
ClinicalTrials.gov study NCT06547749. IPD Sharing: Not stated. Countries: 0. Publications: 5.
Effect of the Mediterranean Diet on Lung Function in Smokers Without Previous Respiratory Disease
ClinicalTrials.gov study NCT03362372. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Wireless Assessment of Respiratory and Circulatory Distress in Chronic Obstructive Pulmonary Disease - Validation Study
ClinicalTrials.gov study NCT04248842. IPD Sharing: NO. Countries: 1. Publications: 1.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.