Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
73
datasets available to search
ShareScore release 0.9.0
Dataset results
73 results for “structural disorder”
Latent Structure of Multi-level Assessments and Predictors of Outcomes in Psychiatric Disorders
ClinicalTrials.gov study NCT02450240. IPD Sharing: Not stated. Countries: 1. Publications: 14.
The genetic architecture of human brainstem structures and their involvement in common brain disorders
<p>GWAS data described in Elvsåshagen, Bahrami, ..., Kaufmann. The genetic architecture of human brainstem structures and their involvement in common brain disorders (https://www.biorxiv.org/content/10.1101/811711v1).</p>
Data from: The influence of disorder on the exciton spectra in two-dimensional structures
<p>We study the joint effect of disorder and Coulomb interaction screening on the exciton spectra in two-dimensional (2D) structures. These can be van der Waals structures or heterostructures of organic (polymeric) semiconductors as well as inorganic substances like transition metal dichalcogenides. We consider 2D screened hydrogenic problem with Rytova - Keldysh interaction by means if so-called fractional Scrodinger equation. Our main finding is that above synergy between screening and disorder either destroys the exciton (strong screening) or promote the creation of a bound state, leading to its collapse in the extreme case. Our second finding is energy levels crossing, i.e. the degeneracy (with respect to index µ) of the exciton eigenenergies at certain discrete value of screening radius. Latter effects may also be related to the quantum manifestations of chaotic exciton behavior in above 2D semiconductor structures. Hence, they should be considered in device applications, where the interplay between dielectric screening and disorder is important.</p>
The effects of caregiver's burden on dynamic structure in disorder of consciousness families: An observational study
<p><strong>Introduction: </strong>Disorder of consciousness is a clinical condition due to severe brain damage. The impact of consciousness disorder on the family is characterized by a combination of biopsychosocial factors. The burden and suffering perceived by caregivers can cause psychological distress characterized by anxiety, depression, and physical illness. The aim of the study was to investigate the interaction between family dynamics and caregiver burden.</p> <p><strong>Methods: </strong>We enlisted 35 caregivers of subjects in a minimally conscious state. Two skilled psychologists administered the Olson's Adaptability and Family Cohesion Assessment Scale and the Novak's Burden Inventory Caregiver Scale to assess family function and family burden, respectively.</p> <p><strong>Results: </strong>We found that the caregiver burden correlates with the family adaptability and cohesion, as well as with enmeshment, rigidity, and disengagement.</p> <p><strong>Conclusion: </strong>Findings suggest that the traumatic event does not affect the family structure. Families are able to maintain a balanced functioning and control distress.</p> <p> </p>
Data from: Inferring pathobiology from structural MRI in schizophrenia and bipolar disorder: modeling head motion and neuroanatomical specificity
Despite over 400 peer-reviewed structural MRI publications documenting neuroanatomic abnormalities in bipolar disorder and schizophrenia, the confounding effects of head motion and the regional specificity of these defects are unclear. Using a large cohort of individuals scanned on the same research dedicated MRI with broadly similar protocols, we observe reduced cortical thickness indices in both illnesses, though less pronounced in bipolar disorder. While schizophrenia (n = 226) was associated with wide-spread surface area reductions, bipolar disorder (n = 227) and healthy comparison subjects (n = 370) did not differ. We replicate earlier reports that head motion (estimated from time-series data) influences surface area and cortical thickness measurements and demonstrate that motion influences a portion, but not all, of the observed between-group structural differences. Although the effect sizes for these differences were small to medium, when global indices were covaried during vertex-level analyses, between-group effects became nonsignificant. This analysis raises doubts about the regional specificity of structural brain changes, possible in contrast to functional changes, in affective and psychotic illnesses as measured with current imaging technology. Given that both schizophrenia and bipolar disorder showed cortical thickness reductions, but only schizophrenia showed surface area changes, and assuming these measures are influenced by at least partially unique sets of biological factors, then our results could indicate some degree of specificity between bipolar disorder and schizophrenia.
Brain Structure and Function Before and After Treatment for Post-Traumatic Stress Disorder
ClinicalTrials.gov study NCT00069225. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Multimodal Analysis of Structural Voice Disorders Based on Speech and Stroboscopic Laryngoscope Video
ClinicalTrials.gov study NCT05348031. IPD Sharing: UNDECIDED. Countries: 0. Publications: 9.
Study on Brain Structure and Function of Pain-related Emotion Disorder
ClinicalTrials.gov study NCT03912610. IPD Sharing: UNDECIDED. Countries: 0. Publications: 3.
Data from: The influence of disorder on the exciton spectra in two-dimensional structures
Open the record for dataset details and reuse information.
Data from: Alterations of gray and white matter networks in patients with obsessive-compulsive disorder: a multimodal fusion analysis of structural MRI and DTI using mCCA+jICA
Open the record for dataset details and reuse information.
Data from: Inferring pathobiology from structural MRI in schizophrenia and bipolar disorder: modeling head motion and neuroanatomical specificity
Open the record for dataset details and reuse information.
Alterations in serum microRNA in humans with alcohol use disorders impact cell proliferation and cell death pathways and predict structural and functional changes in brain [rat miRNA-Seq]
GEO Series GSE71697. Rattus norvegicus. 20 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Convergent transcriptomic signatures across brain structures in eating disorders and obsessive compulsive disorder
GEO Series GSE262138. Homo sapiens. 338 samples. Type: Expression profiling by high throughput sequencing.
Antagonistic roles for Ataxin-2 structured and disordered domains in RNP condensatation
GEO Series GSE153985. Drosophila melanogaster. 33 samples. Type: Expression profiling by high throughput sequencing.
Association of epigenetic differences nominated by monozygotic twins discordant for attention-deficit hyperactivity disorder with their brain structures
GEO Series GSE186339. Homo sapiens. 4 samples. Type: Methylation profiling by array.
Structural Variation of Chromosomes in Autism Spectrum Disorder.
GEO Series GSE9222. Homo sapiens. 1318 samples. Type: Genome variation profiling by SNP array; SNP genotyping by SNP array.
Alterations in serum microRNA in humans with alcohol use disorders impact cell proliferation and cell death pathways and predict structural and functional changes in brain [miRNA-Seq]
GEO Series GSE71578. Homo sapiens. 27 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders
GEO Series GSE149733. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Structured and disordered regions of Ataxin-2 contribute differently to the specificity and efficiency of mRNP granule formation
GEO Series GSE196739. Drosophila melanogaster. 2 samples. Type: Other.
Alterations in serum microRNA in humans with alcohol use disorders impact cell proliferation and cell death pathways and predict structural and functional changes in brain
GEO Series GSE71579. Homo sapiens; Mus musculus; Rattus norvegicus; synthetic construct. 133 samples. Type: Non-coding RNA profiling by high throughput sequencing; Non-coding RNA profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.