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54 results for “synthetic genomics”

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geo24/100

Genome-Wide CRISPR Screen Identifies Multiple Synthetic Lethal Targets That Enhance KRAS (G12C) Inhibitor Efficacy

GEO Series GSE240120. Homo sapiens; Mus musculus. 65 samples. Type: Other; Expression profiling by high throughput sequencing.

openGEO-OpenSep 2023View details →
zenodo24/100

Long read genome assembly of species from the synthetic HAMBI bacterial community

<p>We present complete genome sequences of 30 bacterial species that can be used to construct defined synthetic communities that stably form in the laboratory under controlled conditions.</p><p>This repository contains the final genome assemblies, logs, reports/summaries, scripts, and associated computational methods. All genomes were circularized (or in the case of <i>Agrobacterium tumefaciens</i> properly linearized) with the recovery of some small plasmids.</p><p>30 Species from the HAMBI community were sent for Oxford Nanopore or PacBio HiFi sequencing at <a href="https://www.seqcenter.com/">SeqCenter</a> early November 2022. I assembled multiple subsets of the read data for each genome and generated consensus assemblies using <a href="https://github.com/rrwick/Trycycler">Trycycler</a>.</p><p>All sequence data is available under BioProject <a href="https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1047486">PRJNA1047486</a></p><p>This is a mirror of the repository here: <a href="https://gitlab.utu.fi/slhogl/hambiLongRead">https://gitlab.utu.fi/slhogl/hambiLongRead</a></p>

opencc-by-4.0Dec 2023View details →
geo24/100

Genome-Wide CRISPR Screen Identifies Multiple Synthetic Lethal Targets That Enhance KRAS (G12C) Inhibitor Efficacy [RNA-seq-human]

GEO Series GSE240111. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2023View details →
geo24/100

Genome-Wide CRISPR Screen Identifies Multiple Synthetic Lethal Targets That Enhance KRAS (G12C) Inhibitor Efficacy [scRNA-seq]

GEO Series GSE240118. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2023View details →
geo24/100

CRISPR genome-wide synthetic lethality screens of KRAS-driven mouse pancreatic ductal adenocarcinoma cells

GEO Series GSE162065. Mus musculus. 8 samples. Type: Other.

openGEO-OpenNov 2020View details →
geo24/100

A barcoded genome-scale library of inducible alleles reveals principles of synthetic gene control [Seq]

GEO Series GSE158318. Saccharomyces cerevisiae. 341 samples. Type: Expression profiling by high throughput sequencing; Other.

openGEO-OpenOct 2020View details →
geo24/100

Genome-wide CRISPR-Cas9 screen identifies druggable synthetic lethality between LSD1 and MTORC1 in MLL-translocated AML

GEO Series GSE126486. synthetic construct; Homo sapiens. 28 samples. Type: Expression profiling by high throughput sequencing; Other.

openGEO-OpenDec 2019View details →
geo24/100

An integrated toolkit for the analysis of synthetic cellular barcodes in the genome and transcriptome

GEO Series GSE246611. Mus musculus. 88 samples. Type: Expression profiling by high throughput sequencing; Other.

openGEO-OpenNov 2023View details →
geo24/100

Genome-resolved metatranscriptomics reveals conserved root colonization determinants in a synthetic microbiota

GEO Series GSE231841. unidentified soil bacteria; Arabidopsis thaliana. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2023View details →
geo20/100

Synthetic reversed sequences reveal default genomic states [Yeast_RNAseq]

GEO Series GSE252473. Saccharomyces cerevisiae. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2024View details →
geo20/100

A genome-wide analysis of human pluripotent stem cell-derived endothelial cells cultured in synthetic hydrogels compared to standard 2D or 3D cell culture platforms

GEO Series GSE93511. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2017View details →
geo20/100

Synthetic reversed sequences reveal default genomic states [Yeast_ATACseq]

GEO Series GSE252468. Saccharomyces cerevisiae. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJan 2024View details →
geo20/100

Synthetic genomic reconstitution reveals principles of mammalian Hox cluster regulation

GEO Series GSE190906. Mus musculus; Rattus norvegicus. 162 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.

openGEO-OpenDec 2021View details →
geo20/100

Synthetic reversed sequences reveal default genomic states

GEO Series GSE252482. Saccharomyces cerevisiae; Mus musculus. 160 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.

openGEO-OpenJan 2024View details →
geo20/100

Synthetic reversed sequences reveal default genomic states [mESC_ChIP-Seq]

GEO Series GSE252478. Mus musculus. 80 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJan 2024View details →
geo20/100

Synthetic reversed sequences reveal default genomic states [mESC RNAseq]

GEO Series GSE252479. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2024View details →
geo20/100

Genome-wide expression analysis of C. elegans nematodes engineered to stably express a Cas9-derived synthetic transcription factor, fed HT115 scrambled bacteria

GEO Series GSE202213. Caenorhabditis elegans. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2022View details →
geo20/100

Synthetic regulatory genomics uncovers enhancer context dependence at the Sox2 locus

GEO Series GSE206863. Mus musculus. 434 samples. Type: Other; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJan 2023View details →
geo20/100

Synthetic reversed sequences reveal default genomic states [Yeast_ChIPseq]

GEO Series GSE252472. Saccharomyces cerevisiae. 16 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJan 2024View details →
geo20/100

Synthetic reversed sequences reveal default genomic states [mESC_ATACseq]

GEO Series GSE252476. Mus musculus. 20 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJan 2024View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record