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459
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ShareScore release 0.9.0
Dataset results
459 results for “mesenchymal stromal cells”
Gene expression profiles of human Mesenchymal Stromal Cells (MSC) from JAK2+ myeloproliferative neoplasms (MPN)
GEO Series GSE87806. Homo sapiens. 24 samples. Type: Expression profiling by array.
Distinct adipogenic and fibrogenic differentiation capacities of mesenchymal stromal cells from pancreas and white adipose tissue
GEO Series GSE182243. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Interferon Regulatory Factor 7 (IRF7) in aging of adipose-derived mesenchymal stromal cells
GEO Series GSE168533. Mus musculus. 8 samples. Type: Expression profiling by array.
Comparison of mesenchymal stromal cells derived from osteoarthritis and non-osteoarthritis patients
GEO Series GSE267908. Homo sapiens. 6 samples. Type: Expression profiling by array.
Genome-wide analysis of gene expression during adipogenesis in human adipose-derived mesenchymal stromal cells reveals novel patterns of gene expression during adipocyte differentiation
GEO Series GSE77532. Homo sapiens. 32 samples. Type: Expression profiling by array.
Priming integrin alpha5 promotes human mesenchymal stromal cell osteoblast differentiation and osteogenesis
GEO Series GSE18043. Homo sapiens. 12 samples. Type: Expression profiling by array.
DNA methylation of mesenchymal stromal cells in platelet lysate versus fetal calf serum
GEO Series GSE87797. Homo sapiens. 12 samples. Type: Methylation profiling by genome tiling array.
Renal cancer secretome induces migration of mesenchymal stromal cells
GEO Series GSE232951. Homo sapiens. 9 samples. Type: Expression profiling by array.
Gene expression profiles of induced pluripotent mesenchymal stromal cells [Affymetrix]
GEO Series GSE38806. Homo sapiens. 8 samples. Type: Expression profiling by array.
Impact of spaceflight on gene expression in cultured human mesenchymal stem/stromal cell
With technological advancements, human's desire to explore space is growing and more people are staying longer at the international space station (ISS). The impact of microgravity on stem cells (SC) is not fully understood. We explored the impact of microgravity on gene expression profile of cultured mesenchymal stem/stromal cells (MSCs) at the ISS. We also evaluated how the new knowledge gained sheds light on our understanding of human physiology on Earth. Primary cultures of MSCs were expanded at the ISS for 1 or 2 weeks and mRNA was isolated from samples of the cultured cells. Gene expression profiles were determined and compared with samples from real-time ground control cultures. Differential gene expression, gene set enrichment analysis and determination of key genes were performed that revealed for the first time the existence of potential 'master regulators' coordinating a systemic response to microgravity. Cyclin D1 (CCND1), a protein-coding gene that regulates cell cycle progression and CDK kinases, was identified as the most connected regulator at week 1. Further analysis showed the impacted genes from cultured MSCs significantly correlated with known gene pathways associated with cell division, chromosomal segregation and nuclear division, extracellular matrix structure and organization, muscle apoptosis and differentiation. This study exemplifies the utility of space research to advance our understanding of human physiology both on Earth and in space. To investigate the effects of microgravity on MSC growth and understand the differences in gene expression profiles between microgravity and ground control environments, two groups of MSC were sent to the ISS. One group was cultured for one week, while the other was cultured for two weeks, with corresponding control groups processed similarly on Earth. The cells were then preserved and transferred back to the laboratory. Further Gene expression profiles were compared between samples to identify differentially expressed genes.
Cardiac Nestin+ mesenchymal stromal cells enhance healing of ischemic heart through Periostin-mediated M2 macrophage polarization
GEO Series GSE100064. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Mesenchymal Stromal Cells Derived from Human Embryonic Stem Cells, Fetal Limb and Bone Marrow Share a Common Phenotype but are Transcriptionally and Biologically Different [I]
GEO Series GSE100748. Homo sapiens. 80 samples. Type: Expression profiling by array.
MRAP mediated adipocyte differentiation by thymic mesenchymal stromal cells contributes to thymic involution
GEO Series GSE183261. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Myelodysplastic Syndrome haematopoietic Stem and Progenitor Cells manuplate bone marrow mesenchymal stromal cells for their advantage
GEO Series GSE151584. Homo sapiens. 73 samples. Type: Expression profiling by high throughput sequencing.
Infusion of human amniotic epithelial and mesenchymal stromal stem cells as a new therapeutic option for portal hypertension and cirrhosis
GEO Series GSE125955. Rattus norvegicus. 12 samples. Type: Expression profiling by high throughput sequencing.
Bone marrow mesenchymal stromal cells from acute myelogenous leukemia patients demonstrate adipogenic differentiation propensity with implications for leukemia cell support
GEO Series GSE178309. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Impact of azide metabolic glycoengineering and bioorthogonal click chemistry cell-cell tethering in adipose tissue-derived mesenchymal stromal cells
GEO Series GSE231507. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Gene expression in amniotic menbrane-derived cells (mesenchymal stromal cells and epithelial cells) and expression signatures of these two types of cells after IL-10 stimulation
GEO Series GSE78095. Homo sapiens. 16 samples. Type: Expression profiling by array.
To understand the transcriptional changes in human HSPCs induced upon co-culture with OP9M2 Mesenchymal Stromal Cells and their conditioned medium.
GEO Series GSE247652. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing.
Mesenchymal Stromal Cells Play an Analgesic Role through a Npy2r Sensory Neuron-Mediated Lung-to-Brain Axis
GEO Series GSE305716. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.