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395
datasets available to search
ShareScore release 0.9.0
Dataset results
395 results for “rat model”
Transcriptional profiling of dentate granule cells in 4 rat epilepsy models
GEO Series GSE47752. Rattus norvegicus. 172 samples. Type: Expression profiling by array.
Transcriptional profiling of brain tissues from a Q130 Long Evans Knock-in rat model of Huntington’s disease at 2-, 6-, 10-, 12-, 19- and 24-months of age
GEO Series GSE169388. Rattus norvegicus. 397 samples. Type: Expression profiling by high throughput sequencing.
Genomic profile of dextran sulphate sodium-induced colitis model in rats
GEO Series GSE9281. Rattus norvegicus. 42 samples. Type: Expression profiling by array.
Screening for crucial biomarkers of tendon injury and repair in a rat model
GEO Series GSE201161. Rattus norvegicus. 6 samples. Type: Expression profiling by high throughput sequencing.
Next generation sequencing for miRNA profile of blood sample of goiter rat model treated by quemeiteng granule
GEO Series GSE211703. Rattus norvegicus. 18 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Osteoarthritis-related changes in gene expression in knee articular chondrocytes in a rat model of osteoarthritis.
GEO Series GSE42295. Rattus norvegicus. 12 samples. Type: Expression profiling by array.
Adipose-derived mesenchymal stem cells and hPL-enriched secretome impact on osteoarthritis in a rat model
Open the record for dataset details and reuse information.
Ventricular PFA ablation in rat model -Lesion size data analysis
<p>Excel file with the data used for PFA ablation lesion size calculation corresponding to manuscript "Parametric Study of Pulsed Field Ablation With Biphasic Waveforms in an In Vivo Heart Model: The Role of Frequency".</p> <p>The data was extracted after analysis with QuPath software for the different conditions studied.</p>
ACTH-treated rats: a model to study IGFR-PI3K regulon
GEO Series GSE7550. Rattus norvegicus. 10 samples. Type: Expression profiling by array.
Expression data from monoiodoacetate-induced arthritis in a rat model
GEO Series GSE28958. Rattus norvegicus. 12 samples. Type: Expression profiling by array.
Expression data from a model of renal deceased by cardiac death (DCD) donation in rat
GEO Series GSE35555. Rattus norvegicus. 3 samples. Type: Expression profiling by array.
Clenbuterol, X-ray and Tempol treatments on Contusion Rat model
GEO Series GSE5273. Rattus norvegicus. 22 samples. Type: Expression profiling by array.
Endothelial Colony-Forming Cells Dysfunctions Are Associated with Arterial Hypertension in a Rat Model of Intrauterine Growth Restriction
<p>Infants born after intrauterine growth restriction (IUGR) are at risk of developing arterial hypertension at adulthood. The endothelium plays a major role in the pathogenesis of hypertension. Endothelial colony-forming cells (ECFCs), critical circulating components of the endothelium, are involved in vasculo-and angiogenesis and in endothelium repair. We previously described impaired functionality of ECFCs in cord blood of low-birth-weight newborns. However, whether early ECFC alterations persist thereafter and could be associated with hypertension in individuals born after IUGR remains unknown. A rat model of IUGR was induced by a maternal low-protein diet during gestation versus a control (CTRL) diet. In six-month-old offspring, only IUGR males have increased systolic blood pressure (tail-cuff plethysmography) and microvascular rarefaction (immunofluorescence). ECFCs isolated from bone marrow of IUGR versus CTRL males displayed a decreased proportion of CD31+ versus CD146+ staining on CD45− cells, CD34 expression (flow cytometry, immunofluorescence), reduced proliferation (BrdU incorporation), and an impaired capacity to form capillary-like structures (Matrigel test), associated with an impaired angiogenic profile (immunofluorescence). These dysfunctions were associated with oxidative stress (increased superoxide anion levels (fluorescent dye), decreased superoxide dismutase protein expression, increased DNA damage (immunofluorescence), and stress-induced premature senescence (SIPS; increased beta-galactosidase activity, increased p16INK4a, and decreased sirtuin-1 protein expression). This study demonstrated an impaired functionality of ECFCs at adulthood associated with arterial hypertension in individuals born after IUGR.</p>
Evaluation of therapeutic efficacy of Sodium thiosulfate in combating I/R injury in rat brain: Exploring its efficiency further in vascular calcified brain slice model
<p>Cerebral ischemia reperfusion injury (CIR) is one of the clinical manifestations encountered during the management of stroke. High prevalence of intracranial arterial calcification is reported in stroke patients. However, the impact of vascular calcification (VC) in the outcome of CIR and therapeutic interventions remains unclear. Two different experimental models namely carotid artery occlusion and brain slice models were used to evaluate the efficacy of STS in male Wistar rats. IR was inflicted in rat by occluding carotid artery for 30 minutes followed by 24 hr reperfusion after STS (100 mg/kg) administration. Brain slice model was used to reconfirm the results to account blood brain barrier permeability. Further, brain slice tissue was utilised to evaluate the efficacy of STS in VC rat brain by measuring the histological alterations and biochemical parameters.</p> <p> </p>
Surgical procedures of neonatal rat PVS model.
<p>Surgical procedures of neonatal rat PVS model.</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.