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641 results for “Guideline”
Data from: ALS drug development guidances and trial guidelines: consensus and opportunities for alignment
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Data from: The REporting of studies Conducted using Observational Routinely-collected health Data (RECORD) statement: methods for arriving at consensus and developing reporting guidelines
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Guidelines for conducting ethical AI research in neurology: Supplementary materials
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Data from: Translocation tactics: a framework to support the IUCN Guidelines for wildlife translocations and improve the quality of applied methods
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Data from: Physician assessment of pretest probability of malignancy and adherence with guidelines for pulmonary nodule evaluation
The annual incidence of pulmonary nodules is estimated at 1.57 million. Guidelines recommend using an initial assessment of nodule probability of malignancy (pCA). A previous study found that despite this recommendation, physicians did not follow guidelines. METHODS: Physician assessments (N = 337) and two previously validated risk model assessments of pretest probability of cancer were evaluated for performance in 337 patients with pulmonary nodules based on final diagnosis and compared. Physician-assessed pCA was categorized into low, intermediate, and high risk, and the next test ordered was evaluated. RESULTS: The prevalence of malignancy was 47% (n = 158) at 1 year. Physician-assessed pCA performed better than nodule prediction calculators (area under the curve, 0.85 vs 0.75; P < .001 and .78; P = .0001). Physicians did not follow indicated guidelines when selecting the next test in 61% of cases (n = 205). Despite recommendations for serial CT imaging in those with low pCA, 52% (n = 13) were managed more aggressively with PET imaging or biopsy; 12% (n = 3) underwent biopsy procedures for benign disease. Alternatively, in the high-risk category, the majority (n = 103 [75%]) were managed more conservatively. Stratified by diagnosis, 92% (n = 22) with benign disease underwent more conservative management with CT imaging (20%), PET scanning (15%), or biopsy (8%), although three had surgery (8%). CONCLUSIONS: Physician assessment as a means for predicting malignancy in pulmonary nodules is more accurate than previously validated nodule prediction calculators. Despite the accuracy of clinical intuition, physicians did not follow guideline-based recommendations when selecting the next diagnostic test. To provide optimal patient care, focus in the areas of guideline refinement, implementation, and dissemination is needed.
Data from: Measuring and interpreting sexual selection metrics - evaluation and guidelines
(1) Routine assessments of overall sexual selection, including comparisons of its direction and intensity between sexes or species, rely on summary metrics that capture the essence of sexual selection. Nearly all currently employed metrics require population-wide estimates of individual mating success and reproductive success. The resulting sexual selection metrics, however, can heavily and systematically vary with the chosen approaches in terms of sampling, measurement, and analysis. (2) Our review illustrates this variation using the Bateman gradient, a particularly prominent sexual selection metric. It represents the selection gradient on mating success and – given the latter's pivotal role in defining sexual selection – reflects a trait-independent integrative proxy for the maximum strength of sexual selection. Drawing from a recent meta-analysis, we evaluate potential biases arising from study design, data collection, and parameter estimation, and provide suggestions to mitigate such biases in future studies. (3) With respect to study design, we argue that currently almost inexistent manipulative studies must complement the dominating correlative studies to inform us about causality in sexual selection. With respect to data collection, we outline how different measures of mating and reproductive success affect the components of sexual (and natural) selection that are reflected in standard summary metrics. With respect to parameter estimation, we show the potential impact of decisions about data inclusion and the chosen quantitative approach on inferences of sexual selection and its sex difference. (4) We expect this meta-analytical review to aid future studies in providing less biased and more informative estimates of sexual selection.
Figure 8 from: Penev L, Mietchen D, Chavan V, Hagedorn G, Smith V, Shotton D, Ó Tuama É, Senderov V, Georgiev T, Stoev P, Groom Q, Remsen D, Edmunds S (2017) Strategies and guidelines for scholarly publishing of biodiversity data. Research Ideas and Outcomes 3: e12431. https://doi.org/10.3897/rio.3.e12431
Figure 8 - Import of a data paper manuscript from EML file in the ARPHA Writing Tool.
Figure 2 from: Penev L, Mietchen D, Chavan V, Hagedorn G, Smith V, Shotton D, Ó Tuama É, Senderov V, Georgiev T, Stoev P, Groom Q, Remsen D, Edmunds S (2017) Strategies and guidelines for scholarly publishing of biodiversity data. Research Ideas and Outcomes 3: e12431. https://doi.org/10.3897/rio.3.e12431
Figure 2 - Import of specimen records from GBIF, BOLD, iDigBio and PlutoF into ARPHA manuscripts.
Figure 7 from: Faulwetter S, Pafilis E, Fanini L, Bailly N, Agosti D, Arvanitidis C, Boicenco L, Catapano T, Claus S, Dekeyzer S, Georgiev T, Legaki A, Mavraki D, Oulas A, Papastefanou G, Penev L, Sautter G, Schigel D, Senderov V, Teaca A, Tsompanou M (2016) EMODnet Workshop on mechanisms and guidelines to mobilise historical data into biogeographic databases. Research Ideas and Outcomes 2: e10445. https://doi.org/10.3897/rio.2.e10445
Figure 7 - Example of a parsed materials citation in the GoldenGATE-Imagine editor
Figure 7 from: Faulwetter S, Pafilis E, Fanini L, Bailly N, Agosti D, Arvanitidis C, Boicenco L, Capatano T, Claus S, Dekeyzer S, Georgiev T, Legaki A, Mavraki D, Oulas A, Papastefanou G, Penev L, Sautter G, Schigel D, Senderov V, Teaca A, Tsompanou M (2016) EMODnet Workshop on mechanisms and guidelines to mobilise historical data into biogeographic databases. Research Ideas and Outcomes 2: e9774. https://doi.org/10.3897/rio.2.e9774
Figure 7 - Example of a parsed materials citation in the GoldenGATE-Imagine editor
INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery
ClinicalTrials.gov study NCT06965504. IPD Sharing: NO. Countries: 1. Publications: 0.
Effort to Narrow the Gap Between in Accordance With Guidelines and Consent to Treat CHB Population in East of China
ClinicalTrials.gov study NCT04980664. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluation of a Patient Warming Concept Following the German S3 Guideline for Prevention of Intraoperative Hypothermia
ClinicalTrials.gov study NCT02206997. IPD Sharing: Not stated. Countries: 1. Publications: 0.
CCM and Implementation of Guideline-Directed Medical Therapy in Patients With Heart Failure (Fix-GDMT-HF)
ClinicalTrials.gov study NCT06580392. IPD Sharing: NO. Countries: 1. Publications: 0.
The SWITCH (Substitution of High With Low Ultra-processed Soy Protein Foods In a Guideline-based Diet inTervention for Cardiometabolic Health) Trial
ClinicalTrials.gov study NCT06907862. IPD Sharing: YES. Countries: 1. Publications: 0.
Adherence to Clinical Guidelines on Perioperative Diabetes Care
ClinicalTrials.gov study NCT07349199. IPD Sharing: NO. Countries: 1. Publications: 0.
4R for Guideline Indicated BRCA Testing of Breast Center Patients
ClinicalTrials.gov study NCT01320540. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Fetal Growth Restriction: Management Using Two Guidelines - Fetal Growth Antenatal Management Evaluation
ClinicalTrials.gov study NCT05938829. IPD Sharing: NO. Countries: 1. Publications: 0.
Effect of Guidelines on Nurses' Awareness Toward HRP and Maternal Near Miss Cases
ClinicalTrials.gov study NCT06262568. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
A Virtual Heart Failure Optimization Program for Guideline Directed Medical Therapy and Cardiac Rehabilitation
ClinicalTrials.gov study NCT05689086. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.