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1,281 results for “prematurity”
Neural Development and Its Influencing Factors in Premature Infants With Chronic Lung Disease
ClinicalTrials.gov study NCT00155831. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Immunomodulatory Therapy in Women With Autoimmune Premature Ovarian Insufficiency
ClinicalTrials.gov study NCT05586737. IPD Sharing: NO. Countries: 1. Publications: 0.
Prematurity as Predictor of Children's Cardiovascular-renal Health
ClinicalTrials.gov study NCT02147457. IPD Sharing: Not stated. Countries: 1. Publications: 37.
Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity
ClinicalTrials.gov study NCT01203436. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Plane wave Doppler determination of blood flow in retinopathy of prematurity
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Data from: Emerging wild virus of native grass bioenergy feedstock is well established in the Midwestern USA and associated with premature stand senescence
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Data from: Effects of the selective stretch-activated channel blocker GsMtx4 on stretch-induced changes in refractoriness in isolated rat hearts and on ventricular premature beats and arrhythmias after coronary occlusion in swine
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Data from: Population characteristics, mechanisms of primary care and premature mortality in England: a cross-sectional study
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Data from: Drosophila clock is required in brain pacemaker neurons to prevent premature locomotor aging independently of its circadian function
Circadian clocks control many self-sustained rhythms in physiology and behavior with approximately 24-hour periodicity. In many organisms, oxidative stress and aging negatively impact the circadian system and sleep. Conversely, loss of the clock decreases resistance to oxidative stress, and may reduce lifespan and speed up brain aging and neurodegeneration. Here we examined the effects of clock disruptions on locomotor aging and longevity in Drosophila. We found that lifespan was similarly reduced in three arrhythmic mutants (ClkAR, cyc0 and tim0) and in wild-type flies under constant light, which stops the clock. In contrast, ClkAR mutants showed significantly faster age-related locomotor deficits (as monitored by startle-induced climbing) than cyc0 and tim0, or than control flies under constant light. Reactive oxygen species accumulated more with age in ClkAR mutant brains, but this did not appear to contribute to the accelerated locomotor decline of the mutant. Clk, but not Cyc, inactivation by RNA interference in the pigment-dispersing factor (PDF)-expressing central pacemaker neurons led to similar loss of climbing performance as ClkAR. Conversely, restoring Clk function in these cells was sufficient to rescue the ClkAR locomotor phenotype, independently of behavioral rhythmicity. Accelerated locomotor decline of the ClkAR mutant required expression of the PDF receptor and correlated to an apparent loss of dopaminergic neurons in the posterior protocerebral lateral 1 (PPL1) clusters. This neuronal loss was rescued when the ClkAR mutation was placed in an apoptosis-deficient background. Impairing dopamine synthesis in a single pair of PPL1 neurons that innervate the mushroom bodies accelerated locomotor decline in otherwise wild-type flies. Our results therefore reveal a novel circadian-independent requirement for Clk in brain circadian neurons to maintain a subset of dopaminergic cells and avoid premature locomotor aging in Drosophila.
Avascular Retina Area Modeling for Stratification Risk in Retinopathy of Prematurity
<p>Source data</p>
Compliance to Synagis (Palivizumab) Under Daily Pediatrician´s Conditions in Premature Infants 33 - 35 wGA
ClinicalTrials.gov study NCT01077271. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Safety and Efficacy of Lucinactant for Inhalation in Premature Neonates 26 to 32 Weeks Gestational Age
ClinicalTrials.gov study NCT02636868. IPD Sharing: Not stated. Countries: 8. Publications: 0.
The Correlation Between Red Cell Transfusion and Complications of Prematurity
ClinicalTrials.gov study NCT07123948. IPD Sharing: NO. Countries: 1. Publications: 0.
Evaluation of the Success Rate of Prefabricated Versus Conventional Band and Loop Space Maintainers in Children With Prematurely Lost First Primary Molars
ClinicalTrials.gov study NCT06558812. IPD Sharing: Not stated. Countries: 0. Publications: 2.
Refractive Error and Biometry in Retinopathy of Prematurity
ClinicalTrials.gov study NCT03334513. IPD Sharing: Not stated. Countries: 0. Publications: 2.
Effect of Twice Daily Application of Coconut Oil in Reducing Water Loss From Skin of Premature Babies in First Week of Life
ClinicalTrials.gov study NCT01758068. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Novel Predictors of Premature Aging in COPD Patients
ClinicalTrials.gov study NCT06019286. IPD Sharing: Not stated. Countries: 0. Publications: 4.
A Study of Withdrawal Effects With Dapoxetine in the Treatment of Premature Ejaculation
ClinicalTrials.gov study NCT00210613. IPD Sharing: Not stated. Countries: 0. Publications: 2.
Study to Assess the Efficacy, Safety, and Tolerability of Intravitreal Aflibercept Compared to Laser Photocoagulation in Patients With Retinopathy of Prematurity
ClinicalTrials.gov study NCT04101721. IPD Sharing: YES. Countries: 13. Publications: 0.
Steroid Therapy in Autoimmune Premature Ovarian Failure
ClinicalTrials.gov study NCT00001306. IPD Sharing: Not stated. Countries: 1. Publications: 3.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.