Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
5,016
datasets available to search
ShareScore release 0.9.0
Dataset results
5,016 results for “THERAPEUTICS”
Therapeutic targeting MLL degradation pathways in MLL-rearranged leukemia
GEO Series GSE89485. Homo sapiens; Mus musculus. 64 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Pharmacologic degradation of WDR5 suppresses oncogenic activities of SS18-SSX and provides a therapeutic of synovial sarcoma [RNA-seq]
GEO Series GSE272210. Homo sapiens. 28 samples. Type: Expression profiling by high throughput sequencing.
IKAROS and MENIN are Functionally Cooperative Therapeutic Targets in Acute Myeloid Leukemia [RNA-seq]
GEO Series GSE168462. Homo sapiens. 61 samples. Type: Expression profiling by high throughput sequencing.
Single-cell transcriptome profiling reveals blast cell heterogeneity and identifies novel therapeutic target IKZF2 in t(8;21) acute myeloid leukemia (CUT&Tag)
GEO Series GSE267363. Mus musculus. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Hyaluronan driven by epithelial aPKC deficiency remodels the microenvironment and creates a therapeutic vulnerability in mesenchymal colorectal cancer II
GEO Series GSE207778. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
tRNA-derived Small RNAs and their Potential Roles in the Therapeutic Heterogeneity of Sacubitril/valsartan in Heart Failure Patients after Acute Myocardial Infarction
GEO Series GSE207882. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Therapeutic efficacy of human umbilical cord blood-derived mesenchymal stem cells in myocardial repair after infarction
GEO Series GSE13491. Homo sapiens. 12 samples. Type: Expression profiling by array.
The Nrf2-HMOX1 pathway as a therapeutic target for reversing cisplatin resistance in non-small cell lung cancer via ferroptosis inhibition
GEO Series GSE288129. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukemia
GEO Series GSE29799. Homo sapiens; Mus musculus. 30 samples. Type: Expression profiling by array.
Direct microglia replacement reveals pathologic and therapeutic contributions of brain macrophages to a monogenic neurological disease
GEO Series GSE288018. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Type I Interferon: Potential Therapeutic Target for Psoriasis?
GEO Series GSE14905. Homo sapiens. 82 samples. Type: Expression profiling by array.
The Histone Methyltransferase KMT2D is a Critical Mediator of Lineage Plasticity and Therapeutic Response in Castration Resistant Prostate Cancer [LNCaP Bulk RNA-Seq]
GEO Series GSE296115. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Targeting transcription-replication conflicts is an effective therapeutic principle for MYCN-driven neuroblastoma [ChIP-seq_SHEP]
GEO Series GSE152478. Homo sapiens. 18 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Integrated Multiomic Profiling Identifies the Epigenetic Regulator PRC2 as a Therapeutic Target to Counteract Leukemia Immune Escape and Relapse
GEO Series GSE197419. Homo sapiens. 72 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Rhabdoid Tumor: Gene Expression Clues to Pathogenesis and Potential Therapeutic Targets
GEO Series GSE11482. Homo sapiens. 53 samples. Type: Expression profiling by array.
The m6A Reader IGF2BP2 Regulates Glutamine Metabolism and Represents a Therapeutic Target in Acute Myeloid Leukemia [RNA-seq]
GEO Series GSE199204. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Chemical Inhibition of Salt-Inducible Kinase as Therapeutic Strategy in Acute Myeloid Leukemia
GEO Series GSE129863. Homo sapiens; Mus musculus. 22 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
YTHDF1-regulated oncogenic translation program offers a therapeutic target for acute myeloid leukemia
GEO Series GSE184842. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.
Therapeutic SHPRH-146aa encoded by circ-SHPRH dynamically upregulates P21 to inhibit CDKs in neuroblastoma
GEO Series GSE244294. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Resistance to Palbociclib involves multiple mechanisms amenable to targeting with drug holidays or drug switching to improve therapeutic outcome
GEO Series GSE99003. Homo sapiens. 31 samples. Type: Expression profiling by high throughput sequencing; Genome variation profiling by SNP array; SNP genotyping by SNP array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.