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5,016
datasets available to search
ShareScore release 0.9.0
Dataset results
5,016 results for “THERAPEUTICS”
KDM5 inhibition is a novel therapeutic strategy for the treatment of KMT2D mutant lymphomas [1]
GEO Series GSE114492. Homo sapiens. 58 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
The histone methyltransferase SETDB1 contributes to melanoma tumorigenesis and serves as a new potential therapeutic target in BRAF/MEK inhibitor-resistant melanoma [ChIP-seq]
GEO Series GSE109880. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Baseline serum anti-glycan antibodies of 113 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine [Validation Total Ig 1:50]
GEO Series GSE42176. Quercus alba; Pandalus borealis; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius; Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Medicago sativa; Gallus gallus; Ovis aries; Megathura crenulata; Frangula alnus. 113 samples. Type: Protein profiling by protein array.
Whole-genome CRISPR screening identifies N-glycosylation as an essential pathway and a potential novel therapeutic target in CALR-mutant MPN
GEO Series GSE203459. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing; Other.
Therapeutic efficacy of INX-315, a selective CDK2 inhibitor, in solid tumors [MCF7 ATACseq]
GEO Series GSE243147. Homo sapiens. 16 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Combined blockade of B7-H3 and CD47 immune checkpoints is a new therapeutic strategy for β-catenin driven melanomas [single cell CD45+ YUMM 2.1]
GEO Series GSE186382. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Deconstructing replicative senescence heterogeneity of human mesenchymal stem cells at single cell resolution reveals therapeutically targetable senescent cell sub-populations
GEO Series GSE200157. Homo sapiens. 45 samples. Type: Expression profiling by high throughput sequencing.
Therapeutic targeting of Chronic Kidney Disease-associated DAMPs differentially contributing to vascular pathology.
GEO Series GSE236195. Mus musculus. 10 samples. Type: Expression profiling by RT-PCR.
Therapeutic targeting of the NOTCH1 and neddylation pathways in T cell acute lymphoblastic leukemia
GEO Series GSE245370. Mus musculus. 6 samples. Type: Expression profiling by array.
Discovery, delineation and therapeutic targeting of a hyper-translation pathway driving cytokine release syndrome [BMDM_RiboTag-seq]
GEO Series GSE287442. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Identification of three subtypes of triple negative breast cancer with potential therapeutic implications
GEO Series GSE83937. Homo sapiens. 131 samples. Type: Expression profiling by array.
Discovery of a dual PROTAC for degrading WDR5 and Ikaros oncoproteins as therapeutics [ChIP-Seq]
GEO Series GSE175544. Homo sapiens; Drosophila melanogaster. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Exploring the Effect and Mechanisms of Telomerase Inhibition as A Novel Therapeutic Strategy for Glioma [2224, DBTGR-05MG, A172]
GEO Series GSE180874. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Deconstructing the Intercellular Interactome in Vascular Dementia with Focal Ischemia for Therapeutic Applications
GEO Series GSE298799. Mus musculus. 77 samples. Type: Expression profiling by high throughput sequencing.
Baseline serum anti-glycan antibodies of 28 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine [Training IgM 1:50]
GEO Series GSE42020. Medicago sativa; Gallus gallus; Megathura crenulata; Quercus alba; Bothrops moojeni; Pachymenia carnosa; Rhodotorula; Bos taurus; Ovis aries; Mus musculus; Frangula alnus; Senegalia senegal; Dermestes lardarius; Gossypium hirsutum; Pandalus borealis; Homo sapiens. 28 samples. Type: Protein profiling by protein array.
MITF Expression Predicts Therapeutic Vulnerability to p300 Inhibition in Human Melanoma
GEO Series GSE128737. Homo sapiens. 8 samples. Type: Expression profiling by array.
Metallothionein I as a direct link between therapeutic hematopoietic stem/progenitor cells and cerebral protection in stroke
GEO Series GSE95853. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Single-cell transcriptome profiling reveals blast cell heterogeneity and identifies novel therapeutic target IKZF2 in t(8;21) acute myeloid leukemia (ATAC-seq)
GEO Series GSE267232. Mus musculus. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Long-read sequencing for the assessment of therapeutic CRISPR/Cas9 strategy for the removal of aberrant DM1-causing CTG repeats in DMPK gene locus
GEO Series GSE279054. Homo sapiens. 5 samples. Type: Other.
RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer [wild-type and Apc mutant]
GEO Series GSE199622. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.