Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
5,016
datasets available to search
ShareScore release 0.9.0
Dataset results
5,016 results for “THERAPEUTICS”
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer [RNA-Seq]
GEO Series GSE78285. Homo sapiens. 11 samples. Type: Expression profiling by high throughput sequencing.
CoGAPS matrix factorization algorithm identifies AP-2alpha as a feedback mechanism from therapeutic inhibition of the EGFR network
GEO Series GSE80667. Homo sapiens. 96 samples. Type: Expression profiling by array.
Therapeutic targeting of metabolic vulnerabilities in cancers with MLL3/4-COMPASS epigenetic regulator mutations
GEO Series GSE200120. Mus musculus; Homo sapiens. 106 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Inhibitor of apoptosis proteins as promising therapeutic targets in chronic lymphocytic leukemia
GEO Series GSE62533. Homo sapiens. 12 samples. Type: Expression profiling by array.
Extracellular vesicles from hepatocytes are therapeutic for toxin-mediated fibrosis and gene expression in the liver
GEO Series GSE136152. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab
GEO Series GSE30255. Homo sapiens. 5 samples. Type: Genome variation profiling by SNP array.
Preclinical assessment of pan-influenza A virus CRISPR RNA therapeutics in a human lung alveolus chip
GEO Series GSE272709. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer [ATAC-Seq]
GEO Series GSE236588. Homo sapiens. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Mitochondrial fusion is a therapeutic vulnerability of acute myeloid leukemia [PDX shMFN2]
GEO Series GSE222167. Homo sapiens. 10 samples. Type: Expression profiling by array.
Potential Therapeutic Targets for Donor Lung Repair During Human Ex Vivo Lung Perfusion Prior to Transplantation
GEO Series GSE127243. Homo sapiens. 224 samples. Type: Expression profiling by array; Third-party reanalysis.
Therapeutic efficacy of INX-315, a selective CDK2 inhibitor, in solid tumors
GEO Series GSE243154. Mus musculus; Homo sapiens. 130 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
High-throughput 3D glioblastoma model for rapid personalized therapeutic screening
GEO Series GSE290610. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome profiles associated with selenium deficiency dependent oxidative stress identify potential diagnostic and therapeutic targets in liver cancer cells
GEO Series GSE163950. Homo sapiens. 24 samples. Type: Expression profiling by array.
Multi-level omics analysis of dystrophin loss and therapeutic restoration in a murine model
GEO Series GSE64420. Mus musculus; synthetic construct. 22 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
Re-activation of EWS-FLI1 suppressed FOXO1 expression as a novel therapeutic strategy for Ewing´s sarcoma
GEO Series GSE37409. Homo sapiens. 11 samples. Type: Expression profiling by array.
Discovery of a dual PROTAC for degrading WDR5 and Ikaros oncoproteins as therapeutics [GRO-Seq]
GEO Series GSE195729. Homo sapiens. 4 samples. Type: Other.
Efficient and Safe Therapeutic Use of Paired Cas9-Nickases for Primary Hyperoxaluria Type 1
GEO Series GSE245791. Mus musculus. 14 samples. Type: Other.
Targeting H3K4 methylation as a therapeutic strategy for Huntington's disease (ChIP-seq)
GEO Series GSE48960. Mus musculus. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Induced pluripotent stem cell modeling of bone marrow failure and MDS identifies therapeutic targets
GEO Series GSE118378. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
The Histone Methyltransferase KMT2D is a Critical Mediator of Lineage Plasticity and Therapeutic Response in Castration Resistant Prostate Cancer [H3K4me2 ChIP-Seq]
GEO Series GSE293202. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.