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454
datasets available to search
ShareScore release 0.9.0
Dataset results
454 results for “CD34”
Comparative gene expression of CD34+ human hematopoietic progenitor cells upon knockdown of STAT5
GEO Series GSE97552. Homo sapiens. 4 samples. Type: Expression profiling by array.
Expression data from different stages of erythropoiesis from cord derived CD34+ haematopoietic stem cells and human induced pluripotent stem cells
GEO Series GSE92285. Homo sapiens. 27 samples. Type: Expression profiling by array.
Gene expression profiles of CD34+ cells from patients with myelodysplastic syndrome CAA or AML
GEO Series GSE107968. Homo sapiens. 9 samples. Type: Expression profiling by array.
Expression data from CD34+ hematopoietic progenitor cells
GEO Series GSE20505. Homo sapiens. 21 samples. Type: Expression profiling by array.
RNA-seq of healthy CD34+ HSPCs after co-culture with myelodyplastic syndrome patient-derived mesenchymal stromal cells
GEO Series GSE119916. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
CD34+ and Treatment with UTP
GEO Series GSE3005. Homo sapiens. 6 samples. Type: Expression profiling by array.
Molecular pathways of early CD105-positive erythroid cells as compared to CD34-positive common precursor cells by high-sensitive flow cytometric cell sorting and gene expression profiling
GEO Series GSE40893. Homo sapiens. 24 samples. Type: Expression profiling by array.
Gene expression profiling of the early-stage CD34+ differentiation process
GEO Series GSE22092. Homo sapiens. 3 samples. Type: Expression profiling by SAGE.
CD34 negative populations are associated with an increased relapse risk in childhood AML and harbor chemo-resistant leukemia stem cells
GEO Series GSE45249. Homo sapiens. 27 samples. Type: Expression profiling by array.
Diabetes Induces a Transcriptional Signature in Bone Marrow-Derived CD34 + Hematopoietic Stem Cells Predictive of Their Progeny Dysfunction
<p>Abstract</p> <p>Hematopoietic stem/progenitor cells (HSPCs) participate in cardiovascular (CV) homeostasis and generate different types of blood cells including lymphoid and myeloid cells. Diabetes mellitus (DM) is characterized by chronic increase of pro-inflammatory mediators, which play an important role in the development of CV disease, and increased susceptibility to infections. Here, we aimed to evaluate the impact of DM on the transcriptional profile of HSPCs derived from bone marrow (BM). Total RNA of BM-derived CD34<sup>+</sup> stem cells purified from sternal biopsies of patients undergoing coronary bypass surgery with or without DM (CAD and CAD-DM patients) was sequenced. The results evidenced 10566 expressed genes whose 79% were protein-coding genes, and 21% non-coding RNA. We identified 139 differentially expressed genes (<em>p</em>-value < 0.05 and |log2 FC| > 0.5) between the two comparing groups of CAD and CAD-DM patients. Gene Set Enrichment Analysis (GSEA), based on Gene Ontology biological processes (GO-BP) terms, led to the identification of fourteen overrepresented biological categories in CAD-DM samples. Most of the biological processes were related to lymphocyte activation, chemotaxis, peptidase activity, and innate immune response. Specifically, HSPCs from CAD-DM patients displayed reduced expression of genes coding for proteins regulating antibacterial and antivirus host defense as well as macrophage differentiation and lymphocyte emigration, proliferation, and differentiation. However, within the same biological processes, a consistent number of inflammatory genes coding for chemokines and cytokines were up-regulated. Our findings suggest that DM induces transcriptional alterations in HSPCs, which are potentially responsible of progeny dysfunction.</p>
Circulating CD34+ Fibroblast Progenitors Participate in Heart Fibrosis of Allografts in Humans and Mice
GEO Series GSE300168. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
CD34+ monocyte subset is highly susceptible to HIV-1 infection
GEO Series GSE229346. Homo sapiens. 2 samples. Type: Expression profiling by array.
Immunoregulatory potential of erythroid nucleated cells induced from CD34+ progenitors from bone marrow
GEO Series GSE231654. Homo sapiens. 8 samples. Type: Expression profiling by array.
MiRNA expression profile in CD34+/CD105- cells derived from the renal artery after kidney specific ischemic injury.
GEO Series GSE68369. Mus musculus; Homo sapiens. 16 samples. Type: Expression profiling by RT-PCR.
ScienceDex guides
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.