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488
datasets available to search
ShareScore release 0.9.0
Dataset results
488 results for “deep brain stimulation”
Neurophysiology Biomarkers of Cognitive Impairment Associated With Deep Brain Stimulation
ClinicalTrials.gov study NCT05933681. IPD Sharing: NO. Countries: 1. Publications: 0.
Bilateral Closed Loop Deep Brain Stimulation for Freezing of Gait Using Neural and Kinematic Feedback
ClinicalTrials.gov study NCT04043403. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Clinical Evaluation of Subcallosal Cingulate Gyrus Deep Brain Stimulation for Treatment-Resistant Depression
ClinicalTrials.gov study NCT01801319. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Treatment of Pain and Autonomic Dysreflexia in Spinal Cord Injury With Deep Brain Stimulation
ClinicalTrials.gov study NCT02006433. IPD Sharing: NO. Countries: 1. Publications: 0.
Deep Brain Stimulation in Patients With Chronic Treatment Resistant Depression
ClinicalTrials.gov study NCT01973478. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Alteration of Deep Brain Stimulation Parameters for Dystonia
ClinicalTrials.gov study NCT00971854. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Motor Performance in Parkinson's Disease After High Intensive Exercise or Deep Brain Stimulation
ClinicalTrials.gov study NCT01446549. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study Safety and Efficacy of Deep Brain Stimulation (DBS) and Cervical Deep Lymphoid-venous Anastomosis (LVA) in Alzheimer's Disease
ClinicalTrials.gov study NCT07094438. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease
ClinicalTrials.gov study NCT05557864. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Clinical Outcomes for Deep Brain Stimulation
ClinicalTrials.gov study NCT03992625. IPD Sharing: NO. Countries: 1. Publications: 0.
Evaluation of the Influence of Deep Brain Stimulation on the Spinal Deformities Associated With Parkinson's Disease
ClinicalTrials.gov study NCT04524377. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Short- and Long-term Behavioral, Cognitive and Motor Outcomes of Frameless Deep Brain Stimulation in Patients With Parkinson's Disease: a Prospective Observational Study
ClinicalTrials.gov study NCT05752656. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and synaptic plasticity
GEO Series GSE107383. Mus musculus. 4 samples. Type: Methylation profiling by high throughput sequencing.
Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity
GEO Series GSE111703. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Data from: Longitudinal follow-up with VIM Thalamic Deep Brain Stimulation for Dystonic or Essential Tremor
Open the record for dataset details and reuse information.
Expression data from advanced Parkinson's disease (PD) patients leukocytes - prior to and following deep brain stimulation (DBS) treatment in on and off stimulation conditions, and matched healthy con
GEO Series GSE23676. Homo sapiens. 27 samples. Type: Expression profiling by array.
Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and synaptic plasticity
GEO Series GSE107357. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome-wide changes in the Substantia Nigra following Deep Brain Stimulation in the Subthalamic Nuecleus of a PD rat model.
GEO Series GSE263579. Rattus norvegicus. 24 samples. Type: Expression profiling by high throughput sequencing.
Human Splice Junction Arrays of Parkinson's Patients Leukocytes mRNA Pre- and Post-Deep Brain Stimulation
GEO Series GSE37591. Homo sapiens. 11 samples. Type: Expression profiling by array.
Data set_Network-wide modulation of synaptic plasticity and spike patterns in motor circuits by pallidal deep brain stimulation in a dystonia model
<p>This study utilized deep brain stimulation (DBS) of the globus pallidus pars interna (GPi) to investigate its long-term effects on synaptic activity in motor thalamic and motor cortical neurons in an animal model of generalized dystonia (dtsz hamster). Whole-cell recordings were employed to measure synaptic spike patterns, revealing significant changes in DBS-treated animals compared to sham-treated controls. Specifically, we observed reduced interspike intervals (ISI) and increased postsynaptic current (PSC) frequencies. Fast oscillations were also detected in both thalamic and motor cortical neurons, indicating potential modulation of corticothalamocortical loops by GPi-DBS. Notably, while the overall discharge rates of spontaneous and evoked action potentials remained unchanged, DBS treatment led to increased PSC amplitudes and alterations in inhibitory synaptic currents. These findings suggest that GPi-DBS influences both presynaptic and postsynaptic mechanisms of synaptic plasticity. The results further indicate that GPi-DBS disrupts desynchronized neural activity through axonal and synaptic failures, thereby reorganizing neuronal firing patterns and synaptic connectivity within the motor circuit. This modulation provides mechanistic insights into the therapeutic effects of GPi-DBS in alleviating dystonic symptoms.</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.